Anti-Angpt2

Angpt2 Antibody is a IgG polyclonal antibody from Assay Genie with reactivity against Mouse and for use in ELISA, WB, IHC applications. Angpt2 Antibody is a high quality polyclonal antibody for research use only.. Protein function: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal. [The UniProt Consortium]