Anti-ALR

Anti-ALR
Artikelnummer Größe Datenblatt Manual SDB Lieferzeit Menge Preis
ELK-ES4259.50 50 µl - -

10 - 14 Werktage*

169,00 €
ELK-ES4259.100 100 µl - -

10 - 14 Werktage*

283,00 €
 
The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of... mehr
Produktinformationen "Anti-ALR"
The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1). The putative gene product is 42% similar to the scERV1 protein of yeast. The yeast scERV1 gene had been found to be essential for oxidative phosphorylation, the maintenance of mitochondrial genomes, and the cell division cycle. The human gene is both the structural and functional homolog of the yeast scERV1 gene. [provided by RefSeq, Jul 2008], Protein function: [Isoform 1]: FAD-dependent sulfhydryl oxidase that regenerates the redox-active disulfide bonds in CHCHD4/MIA40, a chaperone essential for disulfide bond formation and protein folding in the mitochondrial intermembrane space. The reduced form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with GFER/ERV1, resulting in regeneration of the essential disulfide bonds in CHCHD4/MIA40, while GFER/ERV1 becomes re-oxidized by donating electrons to cytochrome c or molecular oxygen. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/20000. Not yet tested in other applications.. Cellular localization: [Isoform 1]: Mitochondrion intermembrane space. Mitochondrion ., [Isoform 2]: Cytoplasm. Secreted.
Schlagworte: Anti-ALR, Anti-GFER, Anti-hERV1, EC=1.8.3.2, Anti-Hepatopoietin, Anti-Augmenter of liver regeneration, Anti-FAD-linked sulfhydryl oxidase ALR, ALR rabbit pAb
Hersteller: ELK Biotechnology
Hersteller-Nr: ES4259

Eigenschaften

Anwendung: WB, IHC, IF, ELISA
Antikörper-Typ: Polyclonal
Konjugat: No
Wirt: Rabbit
Spezies-Reaktivität: human, mouse, rat
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human GFER. AA range:51-100
MW: 24 kD
Format: Antiserum

Handhabung & Sicherheit

Lagerung: -20°C
Versand: +4°C (International: +4°C)
Achtung
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!
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