Allgemeine Primärantikörper

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Anti-RIG-I, clone Alme-1
Anti-RIG-I, clone Alme-1

Artikelnummer: AG-20B-0009-C100

Recognizes human and mouse RIG-I. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5'-ppp RNA produced during the...
Schlagworte: RIG-1, Retinoic Acid-inducible Gene 1 Protein, DEAD-box Protein 58, Probable ATP-dependent RNA Helicase DDX58
Anwendung: IHC, IP, WB
Wirt: Mouse
Spezies-Reaktivität: human , mouse
484,00 €
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Anti-TFEB
Anti-TFEB

Artikelnummer: A303-673A

Protein function: Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a...
Schlagworte: Anti-TFEB, Anti-BHLHE35, Anti-bHLHe35, Anti-Transcription factor EB, Anti-Class E basic helix-loop-helix protein 35
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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Anti-ZBP1, clone Zippy-1
Anti-ZBP1, clone Zippy-1

Artikelnummer: AG-20B-0010-C100

Recognizes human and mouse ZBP1. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. ZBP1 binds to cytoplasmic DNA and plays a role in host defense against tumors and pathogens. Highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow and spleen.
Schlagworte: Z-DNA-binding Protein 1, Tumor Stroma and Activated Macrophage Protein DLM-1, DNA-dependent Activator of IFN-regulatory...
Anwendung: ICC, IP, WB
Wirt: Mouse
Spezies-Reaktivität: human, mouse
484,00 €
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Anti-SMC1
Anti-SMC1

Artikelnummer: A300-055A

Protein function: Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can...
Schlagworte: Anti-SMC1A, Anti-Sb1.8, Anti-SMC-1A, Anti-DXS423E, Anti-SMC-1-alpha, Anti-SMC protein 1A, Anti-Structural maintenance of...
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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Anti-CD25 (swine), clone PGBL25A
Anti-CD25 (swine), clone PGBL25A

Artikelnummer: WS0625S-100

The monoclonal antibody was produced in ascites fluid, clarified by filtration through a 0.2 micrometer filter.
Schlagworte: Anti-p55, Anti-CD25, Anti-IL2RA, Anti-IL2-RA, Anti-IL-2-RA, Anti-TAC antigen, Anti-IL-2R subunit alpha, Anti-IL-2 receptor...
Anwendung: FC, IHC, Cell Function
Wirt: Mouse
Spezies-Reaktivität: swine
274,00 €
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Anti-Mcl-1 (Myeloid Cell Leukemia-1)
Anti-Mcl-1 (Myeloid Cell Leukemia-1)

Artikelnummer: 600-401-394

Protein function: Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. [The UniProt Consortium]
Schlagworte: Anti-Mcl1, Anti-Bcl-2-related protein EAT/mcl1, Anti-Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
Anwendung: ELISA, WB
Wirt: Rabbit
Spezies-Reaktivität: mouse
684,00 €
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Anti-MOF/MYST1
Anti-MOF/MYST1

Artikelnummer: A300-992A

Protein function: Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of...
Schlagworte: Anti-MOF, Anti-hMOF, Anti-KAT8, Anti-PP7073, Anti-MYST-1, Anti-Lysine acetyltransferase 8, Anti-Histone acetyltransferase...
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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Anti-p14ARF
Anti-p14ARF

Artikelnummer: A300-342A

Protein function: Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein. [The UniProt Consortium]
Schlagworte: Anti-CDKN2, Anti-CDK4I, Anti-MTS-1, Anti-p16INK4A, Anti-p16-INK4, Anti-p16-INK4a, Anti-Multiple tumor suppressor 1,...
Anwendung: WB, IHC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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Anti-GAPDH
Anti-GAPDH

Artikelnummer: A300-641A

Protein function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the...
Schlagworte: Anti-GAPD, Anti-GAPDH, Anti-CDABP0047, EC=1.2.1.12, EC=2.6.99.-, Anti-Peptidyl-cysteine S-nitrosylase GAPDH,...
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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Anti-MafA (IHC)
Anti-MafA (IHC)

Artikelnummer: IHC-00352

Protein function: Acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Regulates the insulin gene transcription. Involved...
Schlagworte: Anti-Mafa, Anti-Transcription factor MafA, Anti-Pancreatic beta-cell-specific transcriptional activator, Anti-V-maf...
Anwendung: IHC
Wirt: Rabbit
Spezies-Reaktivität: mouse
ab 164,00 €
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Anti-53BP1
Anti-53BP1

Artikelnummer: A300-272A

Protein function: Double-strand break (DSB) repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR) during antibody genesis (PubMed:12364621, PubMed:22553214, PubMed:23333306, PubMed:17190600, PubMed:21144835, PubMed:28241136). Plays a key role in the repair of...
Schlagworte: Anti-53BP1, Anti-p53BP1, Anti-p53-binding protein 1, Anti-TP53-binding protein 1
Anwendung: WB, IP, IHC
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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Anti-Matrin 3
Anti-Matrin 3

Artikelnummer: A300-591A

Protein function: May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. [The UniProt Consortium]
Schlagworte: Anti-MATR3, Anti-Matrin-3, Anti-KIAA0723
Anwendung: WB, IP, IHC, IHC-IF
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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