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Artikelnummer: AG-20B-0009-C100
Recognizes human and mouse RIG-I. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5'-ppp RNA produced during the...
Schlagworte: | RIG-1, Retinoic Acid-inducible Gene 1 Protein, DEAD-box Protein 58, Probable ATP-dependent RNA Helicase DDX58 |
Anwendung: | IHC, IP, WB |
Wirt: | Mouse |
Spezies-Reaktivität: | human , mouse |
484,00 €
Artikelnummer: A303-673A
Protein function: Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a...
Schlagworte: | Anti-TFEB, Anti-BHLHE35, Anti-bHLHe35, Anti-Transcription factor EB, Anti-Class E basic helix-loop-helix protein 35 |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Artikelnummer: AG-20B-0010-C100
Recognizes human and mouse ZBP1. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. ZBP1 binds to cytoplasmic DNA and plays a role in host defense against tumors and pathogens. Highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow and spleen.
Schlagworte: | Z-DNA-binding Protein 1, Tumor Stroma and Activated Macrophage Protein DLM-1, DNA-dependent Activator of IFN-regulatory... |
Anwendung: | ICC, IP, WB |
Wirt: | Mouse |
Spezies-Reaktivität: | human, mouse |
484,00 €
Artikelnummer: A300-055A
Protein function: Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can...
Schlagworte: | Anti-SMC1A, Anti-Sb1.8, Anti-SMC-1A, Anti-DXS423E, Anti-SMC-1-alpha, Anti-SMC protein 1A, Anti-Structural maintenance of... |
Anwendung: | WB, IP, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Artikelnummer: WS0625S-100
The monoclonal antibody was produced in ascites fluid, clarified by filtration through a 0.2 micrometer filter.
Schlagworte: | Anti-p55, Anti-CD25, Anti-IL2RA, Anti-IL2-RA, Anti-IL-2-RA, Anti-TAC antigen, Anti-IL-2R subunit alpha, Anti-IL-2 receptor... |
Anwendung: | FC, IHC, Cell Function |
Wirt: | Mouse |
Spezies-Reaktivität: | swine |
274,00 €
Artikelnummer: 600-401-394
Protein function: Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. [The UniProt Consortium]
Schlagworte: | Anti-Mcl1, Anti-Bcl-2-related protein EAT/mcl1, Anti-Induced myeloid leukemia cell differentiation protein Mcl-1 homolog |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | mouse |
684,00 €
Artikelnummer: A300-641A
Protein function: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the...
Schlagworte: | Anti-GAPD, Anti-GAPDH, Anti-CDABP0047, EC=1.2.1.12, EC=2.6.99.-, Anti-Peptidyl-cysteine S-nitrosylase GAPDH,... |
Anwendung: | WB, IP, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Artikelnummer: A300-992A
Protein function: Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of...
Schlagworte: | Anti-MOF, Anti-hMOF, Anti-KAT8, Anti-PP7073, Anti-MYST-1, Anti-Lysine acetyltransferase 8, Anti-Histone acetyltransferase... |
Anwendung: | WB, IP, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Artikelnummer: A300-272A
Protein function: Double-strand break (DSB) repair protein involved in response to DNA damage, telomere dynamics and class-switch recombination (CSR) during antibody genesis (PubMed:12364621, PubMed:22553214, PubMed:23333306, PubMed:17190600, PubMed:21144835, PubMed:28241136). Plays a key role in the repair of...
Schlagworte: | Anti-53BP1, Anti-p53BP1, Anti-p53-binding protein 1, Anti-TP53-binding protein 1 |
Anwendung: | WB, IP, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Artikelnummer: A300-342A
Protein function: Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein. [The UniProt Consortium]
Schlagworte: | Anti-CDKN2, Anti-CDK4I, Anti-MTS-1, Anti-p16INK4A, Anti-p16-INK4, Anti-p16-INK4a, Anti-Multiple tumor suppressor 1,... |
Anwendung: | WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 164,00 €
Artikelnummer: A300-591A
Protein function: May play a role in transcription or may interact with other nuclear matrix proteins to form the internal fibrogranular network. In association with the SFPQ-NONO heteromer may play a role in nuclear retention of defective RNAs. [The UniProt Consortium]
Schlagworte: | Anti-MATR3, Anti-Matrin-3, Anti-KIAA0723 |
Anwendung: | WB, IP, IHC, IHC-IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Artikelnummer: IHC-00352
Protein function: Acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Regulates the insulin gene transcription. Involved...
Schlagworte: | Anti-Mafa, Anti-Transcription factor MafA, Anti-Pancreatic beta-cell-specific transcriptional activator, Anti-V-maf... |
Anwendung: | IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | mouse |
ab 164,00 €