Products from Chimerigen Laboratories
Chimerigen develops and manufactures unique, immunoglobulin-based, chimeric fusion proteins and related research products using advanced cellular and molecular biological techniques. These reagents are used successfully in basic biomedical and applied research.
More information at: www.adipogen.com/chimerigen
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![SDF-1alpha [CXCL12] (human):Fc (human) (rec.)](/custom/plugins/NetiThemeBiomol/Resources/Themes/Frontend/Biomol/frontend/_public/src/img/no-picture.jpg "SDF-1alpha [CXCL12] (human):Fc (human) (rec.)")
SDF-1alpha [CXCL12] (human):Fc (human) (rec.)
Item number: CHI-HF-210SDF1A-C050
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine that belongs to the CXC chemokine subfamily. SDF1 is widely expressed in various organs including heart, liver, brain, kidney, skeletal muscle, and lymphoid organs, and is highly conserved between species. SDF1 is...
| Keywords: | SDF1, CXCL12, CXCL12, C-X-C Motif Chemokine 12, PBSF, SCYB12, TLSF, TPAR1 |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~35 kD |
369.00€
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Tim-1 (human):Fc (human) (rec.)
Item number: CHI-HF-210T1-C100
The extracellular domain of human Tim-1 (aa 21-295) is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant...
| Keywords: | TIM, KIM1, KIM-1, TIM-1, TIMD-1, HAVCR1, HAVcr-1, Kidney injury molecule 1, T-cell membrane protein 1, Hepatitis A virus... |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
523.00€
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Tim-3 (human):Fc (human) (rec.)
Item number: CHI-HF-210T3-C100
The extracellular domain of human Tim-3 (aa 22-200) is fused to the N-terminus of the Fc region of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant...
| Keywords: | TIM3, TIM-3, TIMD-3, HAVCR2, HAVcr-2, T-cell membrane protein 3, Hepatitis A virus cellular receptor 2, T-cell... |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
523.00€
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IL-15 (mutant) (human):Fc (mouse) (rec.) (Biotin)
Item number: CHI-HF-21115MBI-1
The extracellular domain of human IL-15 (aa 20-359) including mutations at Q148D and Q156D is fused at the C-terminus to the Fc portion of mouse IgG2a. Lyophilized. In PBS and 0.09% sodium azide. This mutant IL-15/Fc fusion protein specifically binds to the IL-15R, competitively inhibits IL-15-triggered cell...
| Keywords: | IL15, IL-15, Interleukin-15 |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
512.00€
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CD152 [CTLA-4] (human):Fc (mouse) (rec.)
Item number: CHI-HF-211A4-C100
CD152 [CTLA-4] and CD28, together with their ligands B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD152 and CD28 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. Both CD152 and CD28 are composed of a...
| Keywords: | CTLA4, CD152, CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4 |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
209.00€
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CD275 [B7-H2] (human):Fc (mouse) (rec.)
Item number: CHI-HF-211B7H2-C100
Human B7-H2 is a member of the growing B7 family of immune costimulatory proteins. Other family members include B7-1, B7-2, B7-H1 (PD-L1), PD-L2 and B7-H3. B7 proteins are members of the immunoglobulin (Ig) superfamily, the extracellular domains contain 2 Ig-like domains and all members have short cytoplasmic...
| Keywords: | B7H2, B7-H2, CD275, B7RP-1, ICOSLG, ICOS ligand, B7 homolog 2, B7-related protein 1, B7-like protein Gl50, B7-H2, ICOS... |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
429.00€
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CD276 [B7-H3] (human):Fc (mouse) (rec.)
Item number: CHI-HF-211B7H3-C100
B7-H3(4Ig) or B7-H3b has two additional Ig-like domains (one V- type and one C- type) and shows a ubiquituous expression pattern. B7-H3(4Ig) is expressed on dendritic cells as well as activated T, B and NK cells. Human (4Ig) binding to an undefined receptor has shown to be inhibitory to NK cell illing and cytokine...
| Keywords: | B7H3, CD276, B7-H3, PSEC0249, 4Ig-B7-H3, B7 homolog 3, CD276 antigen, Costimulatory molecule, B7-H3 |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
429.00€
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B7-H3(4Ig) [B7-H3b] (human):Fc (mouse) (rec.)
Item number: CHI-HF-211B7H3B-C100
B7-H3(4Ig) or B7-H3b has two additional Ig-like domains (one V- type and one C- type) and shows a ubiquituous expression pattern. B7-H3(4Ig) is expressed on dendritic cells as well as activated T, B and NK cells. Human (4Ig) binding to an undefined receptor has shown to be inhibitory to NK cell illing and cytokine...
| Keywords: | B7H3, CD276, B7-H3, PSEC0249, 4Ig-B7-H3, B7 homolog 3, CD276 antigen, Costimulatory molecule, B7-H3 |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
429.00€
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B7-H4 (human):Fc (mouse) (rec.)
Item number: CHI-HF-211B7H4-C100
The extracellular domain of human B7-H4 (aa 29-258) is fused to the N-terminus of the Fc region of mouse IgG2a. B7-H4 protein function: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell...
| Keywords: | B7H4, VTCN1, B7h.5, Protein B7S1, T-cell costimulatory molecule B7x, Immune costimulatory protein B7-H4, V-set... |
| Application: | Inhibitor of anti-CD3-induced proliferation of stimulated human T cells |
| Expressed in: | Hamster cells |
| Origin: | human |
457.00€
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B7-H6 (human):Fc (mouse) (rec.)
Item number: CHI-HF-211B7H6-C100
B7-H6 is a glycosylated member of the B7 family of immune costimulatory proteins. Orthologs in mouse and rat have not been identified. The Ig-like V domain mediates 1:1 stoichiometric binding of B7-H6 to NKp30 expressed on NK cells. It does not show binding to NKp44, NKp46, or NKG2D. Ligation of NKp30 by B7-H6...
| Keywords: | B7H6, B7-H6, NCR3LG1, B7 homolog 6, Natural cytotoxicity triggering receptor 3 ligand 1, |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~80 kD |
429.00€
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CD134 [OX40] (human):Fc (mouse) (rec.)
Item number: CHI-HF-211CD134-C100
CD134 (OX40) is a T cell activation antigen structurally belonging to a lymphocyte-specific subgroup of the nerve growth factor and tumor necrosis factor receptor superfamily, which also includes the T cell antigen CD27, B cell antigen CD40, FAS antigen and the T cell activation antigen 4-1BB. The human CD134...
| Keywords: | CD134, TXGP1L, TNFRSF4, ACT35 antigen, OX40L receptor, Tumor necrosis factor receptor superfamily member 4, TAX... |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~65 kD |
429.00€
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CD137 (human):Fc (mouse) (rec.)
Item number: CHI-HF-211CD137-C100
Human CD137 (4-1BB) is a costimulatory molecule of the tumor necrosis factor (TNF) receptor superfamily. The glycoprotein 4-1BB is expressed mainly on activated CD4+ and CD8+ T cells and binds to a high-affinity ligand (4-1BBL) expressed on several antigen-presenting cells such as macrophages and activated B cells....
| Keywords: | CD137, CDw137, TNFRSF9, T-cell antigen ILA, 4-1BB ligand receptor, T-cell antigen 4-1BB homolog, Tumor necrosis factor... |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~55 kD |
429.00€
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