Products from Chimerigen Laboratories
Chimerigen develops and manufactures unique, immunoglobulin-based, chimeric fusion proteins and related research products using advanced cellular and molecular biological techniques. These reagents are used successfully in basic biomedical and applied research.
More information at: www.adipogen.com/chimerigen
No results were found for the filter!
IL-10Ralpha (human):Fc (human) (rec.)
Item number: CHI-HF-21010RA-C050
CD210, also known as IL10RA, is a subunit for the interleukin-10 receptor. IL10RA has also been designated CDW210A (cluster of differentiation W210A). It is structurally related to interferon receptors. CD210 has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of...
| Keywords: | IL10R, CD210, IL10RA, IL-10R1, CDw210a, IL-10RA, IL-10R subunit 1, IL-10R subunit alpha, IL-10 receptor subunit alpha,... |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~70 kD |
391.00€
*
IL-12 (human):Fc (human) (rec.)
Item number: CHI-HF-21012-C025
Interleukin-12 (IL-12), also known as Natural Killer Cell Stimulatory Factor (NKSF) or Cytotoxic Lymphocyte Maturation Factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. IL-12 is produced by macrophages and B lymphocytes and has been shown to have...
| Keywords: | IL12A, NKSF1, IL-12A, CLMF p35, IL-12 subunit p35, Interleukin-12 subunit alpha, NK cell stimulatory factor chain 1,... |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
468.00€
*
IL-15 (mutant) (human):Fc (human) (rec.)
Item number: CHI-HF-21015M-C050
The extracellular domain of human IL-15 (aa 20-359) including mutations at Q148D and Q156D is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. This mutant IL-15/Fc fusion protein specifically binds to the IL-15R, competitively inhibits IL-15-triggered cell...
| Keywords: | IL15, IL-15, Interleukin-15 |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
484.00€
*
IL-23R (human):Fc (human) (rec.)
Item number: CHI-HF-21023R-C100
Interleukin-23 receptor (IL-23R), is a member of the type I cytokine receptor family, type 2 subfamily. It is expressed by monocytes, Th1, Th0, NK and dendritic cells. Isoform 1 is specifically expressed in NK cells. IL-23 functions in innate and adaptive immunity and may participate in acute response to infection...
| Keywords: | IL23R, IL-23R, IL-23 receptor, Interleukin-23 receptor, Interleukin-23 Receptor |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
418.00€
*
IL-24 (human):Fc (human) (rec.)
Item number: CHI-HF-21024-C025
IL-24 is a cytokine belonging to the IL-10 family of cytokines that signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. This interleukin is also known as melanoma differentiation-associated 7 (mda-7) due to its discovery as a tumour suppressing protein. IL-24 appears to control cell...
| Keywords: | MDA7, IL24, MDA-7, IL-24, Interleukin-24, Suppression of tumorigenicity 16 protein, Melanoma differentiation-associated... |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
468.00€
*
IL-27 (human): Fc (human) (rec.)
Item number: CHI-HF-21027-C050
Unfortunately, most cytokines have short circulating half-lives. With the creation of a group of new immunoglobulin- based cytokine fusion proteins, in which a cytokine sequence had been genetically fused to the hinge, CH2 and CH3 regions of an immunoglobulin, these cytokine fusion proteins possess both the...
| Keywords: | p28, IL27, IL27A, IL27-A, IL-27-A, IL-27 subunit alpha, Interleukin-27 subunit alpha, EBI3, IL27B, IL-27B, IL-27 subunit... |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
457.00€
*
IL-33 (human):Fc (human) (rec.)
Item number: CHI-HF-21033-C050
Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released upon cell lysis. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed...
| Keywords: | IL33, C9orf26, Interleukin-33, IL-1F11, NF-HEV |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~50 kD |
391.00€
*
CD152 [CTLA-4] (human):Fc (human) (rec.)
Item number: CHI-HF-210A4-C100
The extracellular domain of human CD152 [CTLA-4] is fused at the C-terminus to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Binds both CD80 (B7-1) and CD86 (B7-2) with high affinity and inhibits CD28 signaling competitively. Kills the target cell completely. CD152 [CTLA-4] and CD28,...
| Keywords: | CTLA4, CD152, CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4 |
| Application: | Bioassays |
| Expressed in: | Mouse cells |
| Origin: | human |
From 121.00€
*
CD275 [B7-H2] (human):Fc (human) (rec.)
Item number: CHI-HF-210B7H2-C100
The extracellular domain of human CD275 [B7-H2] (aa 1-256) is fused to the N-terminus of the Fc region of human IgG1.
| Keywords: | B7H2, B7-H2, CD275, B7RP-1, ICOSLG, ICOS ligand, B7 homolog 2, B7-like protein Gl50, B7-related protein 1 |
| Application: | Stimulator of human T cell proliferation in the presence of anti-CD3 |
| Expressed in: | Hamster cells |
| Origin: | human |
429.00€
*
B7-H4 (human):Fc (human) (rec.)
Item number: CHI-HF-210B7H4-C100
The extracellular domain of human B7-H4 (aa 29-258) is fused to the N-terminus of the Fc region of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. B7H4 is a B7 family member that negatively regulates T cell immunity by inhibiting of T cell proliferation, cytokine production, and cell cycle progression....
| Keywords: | B7h.5, Protein B7S1, T-cell costimulatory molecule B7x, Immune costimulatory protein B7-H4, V-set domain-containing T-cell... |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
457.00€
*
CCL20 (human):Fc (human) (rec.)
Item number: CHI-HF-210CCL20-C050
Macrophage Inflammatory Protein-3 (MIP3A) or Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or is a small cytokine belonging to the CC chemokine family that attracts immature dendritic cells and memory T lymphocytes, both expressing CCR6. Depending on the cell type, this...
| Keywords: | LARC, CCL20, Chemokine (C-C motif) ligand 20, LARC, MIP-3A, ST38, Scya20, Exodus-1 |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~38 kD |
369.00€
*
CD134 [OX40] (human):Fc (human) (rec.)
Item number: CHI-HF-210CD134-C050
CD134 (OX40) is a T cell activation antigen structurally belonging to a lymphocyte-specific subgroup of the nerve growth factor and tumor necrosis factor receptor superfamily, which also includes the T cell antigen CD27, B cell antigen CD40, FAS antigen and the T cell activation antigen 4-1BB. The human CD134...
| Keywords: | CD134, TXGP1L, TNFRSF4, ACT35 antigen, OX40L receptor, Tumor necrosis factor receptor superfamily member 4, TAX... |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
380.00€
*