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Products from Chimerigen Laboratories
Chimerigen develops and manufactures unique, immunoglobulin-based, chimeric fusion proteins and related research products using advanced cellular and molecular biological techniques. These reagents are used successfully in basic biomedical and applied research.
More information at: www.adipogen.com/chimerigen
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Item number: CHI-HF-20001A-C010
The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism. IL-1alpha was reported to be more widely and constitutively expressed and has intracellular functions,...
| Keywords: | IL1A, IL1F1, IL-1 alpha, Hematopoietin-1, Interleukin-1 alpha, Interleukin-1alpha, IL-1F1, IL-1A |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~19 kD |
248.00€
*
Item number: CHI-HF-20121-C010
Interleukin-21 (IL-21) is a key factor in the transition between innate and adaptive immune responses secreted by activated T cells. The IL-21 receptor (IL-21R) is expressed in lymphoid tissue, in particular by NK, B, T and dendritic cells, macrophages and endothelial cells. Recent evidence suggests that IL-21 plays...
| Keywords: | IL21, Za11, IL-21, Interleukin-21, Interleukin-21 |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~18 kD |
248.00€
*
Item number: CHI-HF-201FLT3L-C010
FMS-like tyrosine kinase 3 ligand (FLT3L) acts as a growth factor that increases the number of immune cells (lymphocytes (B cells and T cells)) by activating the hematopoietic progenitors. It binds to FLT3 (CD135) which is found on multipotent progenitor (MPP) and common lymphoid progenitor (CLP) cells in mice....
| Keywords: | Flt3L, FLT3LG, SL cytokine, Flt3 ligand, Fms-related tyrosine kinase 3 ligand, FLT3L, FMS-like Tyrosine Kinase 3 Ligand |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~25 kD |
248.00€
*
Item number: CHI-HF-21010-C010
Unfortunately, most cytokines have short circulating half-lives. With the creation of a group of new immunoglobulin- based cytokine fusion proteins, in which a cytokine sequence had been genetically fused to the hinge, CH2 and CH3 regions of an immunoglobulin, these cytokine fusion proteins possess both the...
| Keywords: | IL10, CSIF, IL-10, Interleukin-10, Cytokine synthesis inhibitory factor |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
264.00€
*
Item number: CHI-MF-11002-C010
Unfortunately, most cytokines have short circulating half-lives. With the creation of a group of new immunoglobulin- based cytokine fusion proteins, in which a cytokine sequence had been genetically fused to the hinge, CH2 and CH3 regions of an immunoglobulin, these cytokine fusion proteins possess both the...
| Keywords: | Il2, TCGF, IL-2, Interleukin-2, T-cell growth factor |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | mouse |
From 226.00€
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Item number: CHI-MR-10022-C010
Protein function: [The Uniprot Consortium]
| Keywords: | Il22, Il22a, IL-22, IL-TIF, IL-22a, IL-TIF alpha, Interleukin-22, Interleukin-22a, IL-10-related T-cell-derived-inducible... |
| Application: | Bioassays |
| Expressed in: | E.coli |
| Origin: | mouse |
From 209.00€
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Item number: CHI-RR-300CTRP3-C010
CTRP3 (C1qTNF-related protein 3) plays an important role in regulating both embryonic cartilage development and postnatal longitudinal bone growth. CTRP3 stimulation leads to ERK1/2-dependent cell proliferation in human osteosarcoma cell lines.
| Keywords: | C1qtnf3 protein, Protein C1qtnf3, Complement C1q Tumor Necrosis Factor-related Protein 3, Secretory Protein CORS26, C1QTNF3 |
| Application: | Bioassays |
| Expressed in: | E.coli |
| Origin: | rat |
| MW: | ~33 kD |
187.00€
*
Item number: CHI-HR-20602-C010
Protein. The extracellular domain of human IL-2 (aa 21-153) with a N-terminal Met. Source: E. coli. Endotoxin content: 95% (SDS-PAGE). Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation...
| Keywords: | Interleukin-2, Aldesleukin |
| Expressed in: | E.coli |
| MW: | 14 kD |
171.00€
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Item number: CHI-HR-20621-C010
Protein. Human IL-21 (aa 23-155) with a N-terminal Met. Source: E. coli. Endotoxin content: 95% (SDS-PAGE). Interleukin-21 (IL-21) is a key factor in the transition between innate and adaptive immune responses secreted by activated T cells. The IL-21 receptor (IL-21R) is expressed in lymphoid tissue, in particular...
| Keywords: | Interleukin-21 |
| Expressed in: | E.coli |
| MW: | 17 kD |
From 275.00€
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Item number: CHI-HF-211FLT3L-C050
Recombinant protein. The extracellular domain of human FLT3L (aa 27-184) is fused to the N-terminus of the Fc region of mouse IgG2a. Source/Host: HEK 293 cells. Purity: >98% (SDS-PAGE). Lyophilized from 0.2µm-filtered solution in PBS. FMS-like tyrosine kinase 3 ligand (FLT3L) acts as a growth factor that increases...
| Keywords: | FLT3L, FMS-like Tyrosine Kinase 3 Ligand |
| Expressed in: | Human cells |
446.00€
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Item number: CHI-HF-201CD28-C100
Recombinant protein. The extracellular domain of human CD28 (aa 19-152) is fused at the C-terminus to a His-tag. Source/Host: HEK 293 cells. Purity: >98% (SDS-PAGE). Lyophilized from 0.2µm-filtered solution in PBS. CD28 and CTLA-4 together with their ligands, CD80 (B7-1) and CD86 (B7-2), constitute one of the...
| Keywords: | T-cell-specific surface glycoprotein CD28, TP44 |
| Expressed in: | Human cells |
418.00€
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Item number: CHI-HF-210GFRAL-C100
Recombinant protein. The extracellular domain of human GFRAL (aa 19-351) is fused to the N-terminus of the Fc region of human IgG1. Measured by its binding ability in a functional ELISA. Source/Host: HEK 293 cells. Purity: >98% (SDS-PAGE). Lyophilized from 0.2µm-filtered solution in PBS. GFRAL (GDNF receptor...
| Keywords: | GDNF Family Receptor alpha-like, Gral, Glial Cellline-derived Neurotrophic Factor Receptor alpha-like, GFR alpha-like,... |
| Expressed in: | Human cells |
523.00€
*