Products from Chimerigen Laboratories
Chimerigen develops and manufactures unique, immunoglobulin-based, chimeric fusion proteins and related research products using advanced cellular and molecular biological techniques. These reagents are used successfully in basic biomedical and applied research.
More information at: www.adipogen.com/chimerigen
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IL-4 (mouse) (rec.) (His)
Item number: CHI-MR-10004-C010
Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts...
| Keywords: | Il4, Il-4, IL-4, BSF-1, Interleukin-4, IGG1 induction factor, B-cell growth factor 1, B-cell stimulatory factor 1,... |
| Application: | Bioassays |
| Expressed in: | E.coli |
| Origin: | mouse |
From 226.00€
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IL-2 (rat) (rec.) (His)
Item number: CHI-RR-30002-C010
Protein function: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells....
| Keywords: | Il2, TCGF, IL-2, Interleukin-2, T-cell growth factor |
| Application: | Bioassays |
| Expressed in: | E.coli |
| Origin: | rat |
209.00€
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IL-23 (human) (rec.)
Item number: CHI-AG-40A-0038-C010
Interleukin-23 (IL-23) is a heterodimeric cytokine and a member of the IL-12 family involved in innate and adaptive immunity. It is composed of the IL-12 p40 chain covalently linked to p19, a chain related to the IL-12 p35 subunit. IL-23 signals through the IL-23 receptor complex, which is composed of the...
| Keywords: | SGRF, IL23A, IL-23-A, IL-23p19, IL-23 subunit alpha, Interleukin-23 subunit p19, Interleukin-23 subunit alpha |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~70 kD |
286.00€
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IL-12 (human) (rec.) (His)
Item number: CHI-HF-20112-C010
Interleukin-12 (IL-12), also known as Natural Killer Cell Stimulatory Factor (NKSF) or Cytotoxic Lymphocyte Maturation Factor (CLMF), is a heterodimeric pleiotropic cytokine made up of a 40 kDa (p40) subunit and a 35 kDa (p35) subunit. IL-12 is produced by macrophages and B lymphocytes and has been shown to have...
| Keywords: | IL12A, NKSF1, IL-12A, CLMF p35, IL-12 subunit p35, Interleukin-12 subunit alpha, NK cell stimulatory factor chain 1,... |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~85 kD |
From 248.00€
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IL-4 (human):Fc (human) (rec.) MultiPack
Item number: CHI-HF-21004-C010
Interleukin-4 (IL-4) is a cytokine produced by type 2 helper T cells, the Th2 cells. These cells tends to make a specific set of lymphokines including IL-4, IL-5, IL-6, IL-10, IL-13, IL-3 and GM-CSF and fail to produce IL-2, IFN-gamma, and lymphotoxin (TNF-beta). In addition, mast cells can produce IL-4. IL-4 exerts...
| Keywords: | IL4, IL-4, BSF-1, Binetrakin, Pitrakinra, Interleukin-4, B-cell stimulatory factor 1, Lymphocyte stimulatory factor 1,... |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
From 209.00€
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IL-10 (human):Fc (human) (rec.) (non-lytic)
Item number: CHI-HF-22010-C010
The extracellular domain of human IL-10 (aa 19-178) is fused at the C-terminus to the Fc portion of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-10 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin-10...
| Keywords: | IL10, CSIF, IL-10, Interleukin-10, Cytokine synthesis inhibitory factor |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
From 264.00€
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IL-1alpha (human) (rec.) (His)
Item number: CHI-HR-20001A-C010
The most prominent members of the interleukin-1 (IL-1) superfamily are IL-1alpha and IL-1beta. They lack a signal peptide and are secreted by an unconventional, endoplasmic reticulum-Golgi-independent mechanism. IL-1alpha was reported to be more widely and constitutively expressed and has intracellular functions,...
| Keywords: | IL1A, IL1F1, IL-1 alpha, Hematopoietin-1, Interleukin-1 alpha, Interleukin-1alpha, IL-1F1, IL-1A |
| Application: | Bioassays |
| Expressed in: | E.coli |
| Origin: | human |
From 209.00€
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Interleukin-8, human recombinant (rHuIL-8) (His)
Item number: CHI-HR-20008-C010
Interleukin-8 (IL-8) was originally discovered as a neutrophil chemotactic and activating factor and is a member of the alpha (CXC) subfamily of chemokines (including also platelet factor 4, GRO, IP-10, etc.). Many cell types, including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells,...
| Keywords: | Interleukin-8, CXCL8, C-X-C Motif Chemokine 8, Emoctakin, GCP-1, LAI, MDNCF, MONAP, NAP-1, NCF, TCF |
| Application: | Bioassays |
| Expressed in: | E.coli |
| Origin: | human |
From 187.00€
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IL-15 (human) (rec.) (His)
Item number: CHI-HR-20015-C010
Interleukin-15 (IL-15) has a broad spectrum of biological activities. It is crucial for the development, proliferation, survival and differentiation of multiple cells from both innate and adaptive immune systems. IL-15 up-regulation has a central role in the development of several autoimmune or chronic inflammatory...
| Keywords: | IL15, IL-15, Interleukin-15, Interleukin-15 |
| Application: | Bioassays |
| Expressed in: | E.coli |
| Origin: | human |
| MW: | ~14 kD |
From 187.00€
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IL-6 (human) (rec.) (His)
Item number: CHI-HF-20106-C010
Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It...
| Keywords: | CDF, IL6, IL-6, BSF-2, IFNB2, IFN-beta-2, Interleukin-6, Interferon beta-2, Hybridoma growth factor, CTL differentiation... |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~22 kD |
From 132.00€
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IL-21 (mutant) (human) (rec.) (His)
Item number: CHI-HR-20021M-C010
Interleukin-21 (IL-21) is a key factor in the transition between innate and adaptive immune responses secreted by activated T cells. The IL-21 receptor (IL-21R) is expressed in lymphoid tissue, in particular by NK, B, T and dendritic cells, macrophages and endothelial cells. Recent evidence suggests that IL-21 plays...
| Keywords: | IL21, Za11, IL-21, Interleukin-21 |
| Application: | Bioassays |
| Expressed in: | E.coli |
| Origin: | human |
From 209.00€
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BMP-2, human recombinant (rHuBMP-2) (His)
Item number: CHI-HR-200BMP2-C010
The extracellular domain of human BMP-2 (aa 289-396) is fused at the C-terminus to a His-tag. Bone morphogenetic protein 2 (BMP-2) is a member of the BMP subgroup of the TGF-beta superfamily. It plays a dominant role in embryonic dorsalventral patterning, organogenesis, limb bud formation and bone formation and...
| Keywords: | BMP2, Bone Morphogenetic Protein 2 |
| Application: | Bioassays |
| Expressed in: | E.coli |
| Origin: | human |
From 209.00€
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