Products from Chimerigen Laboratories
Chimerigen develops and manufactures unique, immunoglobulin-based, chimeric fusion proteins and related research products using advanced cellular and molecular biological techniques. These reagents are used successfully in basic biomedical and applied research.
More information at: www.adipogen.com/chimerigen
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CD28 (mouse):Fc (mouse) (rec.)
Item number: CHI-MF-110CD28-C200
The extracellular domain of mouse CD28 (aa 21-149) is fused to the N-terminus of the Fc region of mouse IgG2a. CD28 and CTLA-4 together with their ligands, CD80 (B7-1) and CD86 (B7-2), constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally...
| Keywords: | CD28, Cd28, T-cell-specific surface glycoprotein CD28 |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | mouse |
484.00€
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CD80 (mouse):Fc (mouse) (rec.)
Item number: CHI-MF-110CD80-C100
The extracellular domain of mouse CD80 (aa 37-245) is fused to the N-terminus of the Fc region of mouse IgG2a. CD80 (B7-1) and CD86 (B7-2) together with their receptors CD28 and CTLA-4 constitute one of the dominant costimulatory pathways that regulate T cell and B cell responses. Although both CTLA-4 and CD28 can...
| Keywords: | B7, Cd80, CD80, Activation B7-1 antigen, T-lymphocyte activation antigen CD80 |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | mouse |
429.00€
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CD83 (mouse):Fc (mouse) (rec.)
Item number: CHI-MF-110CD83-C050
Mouse CD83 is a 30-35kDa member of the Siglec (or sialic-acid-binding immunoglobulin-like lectin) family of transmembrane proteins. CD83 is a primary marker for dendritic cells. It is also found on B cells, neutrophils, monocytes and macrophages. Except for dendritic cells, CD83 expression is often transient. CD83...
| Keywords: | Cd83, CD83, mCD83, CD83 antigen, |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | mouse |
248.00€
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CD86 (mouse):Fc (mouse) (rec.)
Item number: CHI-MF-110CD86-C100
The extracellular domain of mouse CD86 (aa 26-245) is fused to the N-terminus of the Fc region of mouse IgG2a. CD86 (B7-2) is a 60-100 kDa variably glycosylated protein in the B7 family. B7 family members are transmembrane cell surface molecules that play important roles in immune activation and the maintenance of...
| Keywords: | CD86, Cd86, ETC-1, Activation B7-2 antigen, T-lymphocyte activation antigen CD86, Early T-cell costimulatory molecule 1 |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | mouse |
429.00€
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CD278 [ICOS] (mouse):Fc (mouse) (rec.)
Item number: CHI-MF-110ICOS-C100
The extracellular domain of mouse CD278 [ICOS] (aa 21-142) is fused to the N-terminus of the Fc region of mouse IgG2a. CD278, also called inducible costimulator (ICOS) or CRP1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and...
| Keywords: | CCLP, Icos, CD278, Ailim, CRP-1, CD28-related protein 1, CD28 and CTLA-4-like protein, Inducible T-cell costimulator,... |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | mouse |
429.00€
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Fc (mouse) IgG2a Control (rec.)
Item number: CHI-MF-110IG2A-C100
This product should be used as the control protein for activity tests of fusion proteins including mouse target proteins and mouse IgG2a-Fc domains.
| Keywords: | Ighg, Ig gamma-2A chain C region, A allele, Immunoglobulin heavy chain gamma polypeptide, |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | mouse |
| MW: | ~26 kD |
391.00€
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LYVE-1 (mouse):Fc (mouse) (rec.)
Item number: CHI-MF-110LYVE1-C050
Lymphatic Vessel Endothelial Hyaluronan (HA) Receptor-1 (LYVE-1) is a 60-kDa type I transmembrane glycoprotein that is a member of the Link Protein superfamily. HA is found in the extracellular matrix of most animal tissues and in body fluids. It modulates cell behavior and functions during tissue remodeling,...
| Keywords: | Lyve1, Crsbp1, LYVE-1, CRSBP-1, Extracellular link domain-containing protein 1, Cell surface retention sequence-binding... |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | mouse |
| MW: | ~70 kD |
391.00€
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CD273 [PD-L2] (mouse):Fc (mouse) (rec.)
Item number: CHI-MF-110PDL2-C100
The extracellular domain of mouse CD273 [PD-L2] (aa 20-219) is fused to the N-terminus of the Fc region of mouse IgG2a. T cells require a signal induced by the engagement of the T cell receptor and a costimulatory signal(s) through distinct T cell surface molecules for optimal T cell activation and tolerance. CD273...
| Keywords: | B7dc, PD-L2, CD273, B7-DC, Pdcd1lg2, PD-1 ligand 2, PDCD1 ligand 2, Butyrophilin B7-DC, Programmed death ligand 2,... |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | mouse |
429.00€
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SCF (mouse):Fc (mouse) (rec.)
Item number: CHI-MF-110SCF-C050
The extracellular domain of mouse SCF (aa 26-214) is fused at the C-terminus to the Fc portion of mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Stem cell factor (SCF), also known as cKit ligand (KL), mast cell growth factor (MGF), and steel factor (SLF), is a widely expressed 28-40 kDa type I...
| Keywords: | MGF, SCF, Kitl, Kitlg, sKITLG, Kit ligand, c-Kit ligand, Steel factor, Stem cell factor, Soluble KIT ligand, Mast cell... |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | mouse |
314.00€
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Tim-1 (mouse):Fc (mouse) (rec.)
Item number: CHI-MF-110T1-C100
The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific...
| Keywords: | Kim1, KIM-1, TIM-1, TIMD-1, Havcr1, HAVcr-1, Kidney injury molecule 1, T cell membrane protein 1, T-cell immunoglobulin... |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | mouse |
| MW: | ~70 kD |
523.00€
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Tim-2 (mouse):Fc (mouse) (rec.)
Item number: CHI-MF-110T2-C100
Probable receptor for SEMA4A involved in the regulation of T-cell function. The interaction with SEMA4A enhances T-cell activation.
| Keywords: | Tim2, TIM-2, Timd2, TIMD-2, T-cell membrane protein 2, T-cell immunoglobulin mucin receptor 2, T-cell immunoglobulin and... |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | mouse |
| MW: | ~65 kD |
523.00€
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Tim-3 (mouse):Fc (mouse) (rec.)
Item number: CHI-MF-110T3-C100
The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific...
| Keywords: | Tim3, TIM-3, Havcr2, TIMD-3, HAVcr-2, T-cell membrane protein 3, T-cell immunoglobulin mucin receptor 3, Hepatitis A virus... |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | mouse |
| MW: | ~65 kD |
523.00€
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