Products from Chimerigen Laboratories
Chimerigen develops and manufactures unique, immunoglobulin-based, chimeric fusion proteins and related research products using advanced cellular and molecular biological techniques. These reagents are used successfully in basic biomedical and applied research.
More information at: www.adipogen.com/chimerigen
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IL-18 (human) (rec.) (His)
Item number: CHI-HR-20018-C050
Interleukin-18 (IL-18) is a costimulatory factor for production of interferon-gamma (IFN-gamma) in response to toxic shock and shares functional similarities with IL-12. IL-18 is synthesized as a precursor 24kDa molecule without a signal peptide and must be cleaved to produce an active molecule. IL-1 converting...
| Keywords: | IL18, IGIF, IL-18, IL-1 gamma, Iboctadekin, Interleukin-18, Interleukin-1 gamma, IFN-gamma-inducing factor, Interferon... |
| Application: | Bioassays |
| Expressed in: | E.coli |
| Origin: | human |
484.00€
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IL-35 (mouse):Fc (human) (rec.)
Item number: CHI-MF-11135-C025
The mouse IL-35 complex composed of the Ebi3 subunit (aa 23-228) and the IL-12a (p35) subunit (aa 23-215) is fused through a polypeptide linker to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-35 (IL-35) is a novel IL-12 family cytokine produced by regulatory T cells...
| Keywords: | Interleukin-35, Il12a, IL-12A, CLMF p35, IL-12 subunit p35, Interleukin-12 subunit alpha, Cytotoxic lymphocyte maturation... |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | mouse |
From 325.00€
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IL-35 (human):Fc (human) (rec.)
Item number: CHI-HF-21035-C025
The human IL-35 complex composed of the Ebi3 subunit (aa 21-229) and the IL-12a (p35) subunit (aa 57-253) is fused through a polypeptide linker to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-35 (IL-35) is a novel IL-12 family cytokine produced by regulatory T cells...
| Keywords: | Interleukin-35, NKSF1, IL12A, IL-12A, CLMF p35, IL-12 subunit p35, Interleukin-12 subunit alpha, NK cell stimulatory... |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
286.00€
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Galectin-9 (human):Fc (human) (rec.)
Item number: CHI-HF-210GAL9-C050
The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific...
| Keywords: | Gal-9, LGALS9, Ecalectin, Galectin-9, Tumor antigen HOM-HD-21, Gal-9, Ecalectin, TIM3L, TIM-3 Ligand, T Cell... |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
391.00€
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Tim-4 (human):Fc (mouse) (rec.)
Item number: CHI-HF-211T4-C100
The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific...
| Keywords: | TIM4, TIMD4, TIM-4, TIMD-4, T-cell membrane protein 4, T-cell immunoglobulin mucin receptor 4, T-cell immunoglobulin and... |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~80 kD |
523.00€
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CD274 [B7-H1/PD-L1] (human):Fc (human) (rec.)
Item number: CHI-HF-210PDL1-C100
The extracellular domain of human CD274 [B7-H1] (aa 19-238) is fused to the N-terminus of the Fc region of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Programmed death ligand 1 (PD-L1, B7-H1 or CD274) is a member of the growing B7 family of immune proteins that provide signals for both stimulating...
| Keywords: | B7H1, B7-H1, CD274, PD-L1, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1 |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
429.00€
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IL-10 (mouse):Fc (mouse) (rec.) (non-lytic)
Item number: CHI-MF-12010-C050
The extracellular domain of mouse IL-10 (aa 22-178) is fused at the C-terminus to the Fc portion of a mutant mouse IgG2a. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-10 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin-10...
| Keywords: | Il10, CSIF, IL-10, Interleukin-10, Cytokine synthesis inhibitory factor |
| Application: | Bioassays |
| Expressed in: | Mouse cells |
| Origin: | mouse |
From 303.00€
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Fc (human) IgG1 Control (rec.)
Item number: CHI-HF-210IG1-C100
This product should be used as the control protein for activity tests of fusion proteins including human target proteins and human IgG-Fc domains.
| Keywords: | IGHG1, Ig gamma-1 chain C region, |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~26 kD |
391.00€
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BMP-2 (human):Fc (human) (rec.) (non-lytic)
Item number: CHI-HF-220BMP2-C050
The extracellular domain of human BMP-2 (aa 289-396) is fused at the C-terminus to the Fc portion of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the BMP-2 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Bone...
| Keywords: | BMP2, BMP2A, BMP-2, BMP-2A, Bone morphogenetic protein 2, Bone morphogenetic protein 2A |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
484.00€
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Fc (human) IgG1 Control (rec.) (non-lytic)
Item number: CHI-HF-220IG1-C100
This product should be used as the control protein for activity tests of fusion proteins including human target proteins and human IgG-Fc domains.
| Keywords: | IGHG1, Ig gamma-1 chain C region, |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | ~26 kD |
391.00€
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CD274 [B7-H1/PD-L1] (human):Fc (human) (rec.) (non-lytic)
Item number: CHI-HF-220PDL1-C100
The extracellular domain of human CD274 [B7-H1] (aa 19-238) is fused to the N-terminus of the Fc region of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the CD274 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Programmed...
| Keywords: | B7H1, B7-H1, CD274, PD-L1, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1 |
| Application: | Bioassays |
| Expressed in: | Hamster cells |
| Origin: | human |
429.00€
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CD27 (human) (rec.) (His)
Item number: CHI-HR-200CD27-C050
Human CD27 (aa 21-192) is fused at the C-terminus to a His-tag. CD27 (TNFRSF7) is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a T and B cell co-stimulatory molecule, the activity...
| Keywords: | T14, CD27, TNFRSF7, CD27 antigen, CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor... |
| Application: | Bioassays |
| Expressed in: | E.coli |
| Origin: | human |
380.00€
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