Products from Chemodex
Chemodex Ltd. from Switzerland (founded in 2001 in St. Gallen) are experts in the synthesis of fluorescent substances derived from fluorophores such as coumarin, fluorescein, rhodamine and pyrene. The reagents are used as probes, stains, markers, NIR-labels, pH-sensors, ion indicators, chelators and in other applications (e.g. analytical biochemistry, immunoassays and microscopy). The various products are used by natural science researchers in academia, biotechnology and the pharmaceutical industry.
More information at: www.adipogen.com/chemodex
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7-Dehydrocholesterol
Item number: CDX-D0331-G010
White powder. Soluble in ethanol, chloroform or ethyl acetate. Slightly soluble in DMSO. Insoluble in water. Precursor of cholesterol and vitamin D3. It is reduced to cholesterol by the enzyme 3beta-hydroxysterol-Delta7-reductase (DHCR7) in the last step of cholesterol biosynthesis. Mutations in the gene encoding...
| Keywords: | 7-DHC, NSC 18159, Provitamin D3, Delta7-Cholesterol, (?)-7-Dehydrocholesterol, 3beta-Hydroxy-5,7-cholestadiene,... |
| Application: | Cholesterol & vitamin D3 precursor |
| CAS | 434-16-2 |
| MW: | 384,64 D |
From 109.00€
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Indo-1 pentapotassium salt
Item number: CDX-I0018-M002
Off-white solid. Soluble in water. Fluorescent calcium chelator and indicator with an unusually large shift in fluorescence emission from 480 nm to 400 nm on binding of calcium. Useful for intracellular application.
| Application: | Fluorescent calcium chelator / indicator |
| CAS | 132319-56-3 |
| MW: | 840,05 D |
From 230.00€
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D-Luciferin potassium salt
Item number: CDX-L0009-M050
Light yellow solid. Soluble in DMSO (10mg/ml) or water (10mg/ml). Chemical. CAS: 115144-35-9. Formula: C11H7KN2O3S2. MW: 318.41. D-Luciferin is the most popular and versatile bioluminescent substrate. Firefly luciferase produces light by the ATP-dependent oxidation (Mg2+ as cofactor) of luciferin. It emits a...
| Keywords: | (S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic acid potassium salt,... |
| Application: | Labeling |
| CAS | 115144-35-9 |
| MW: | 318,41 D |
From 46.00€
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FURA 2-AM
Item number: CDX-F0014-M001
Synthetic. Chemical. CAS: 108964-32-5. Formula: C44H47N3O24. MW: 1001.87. Synthetic. The fluorescent probe FURA 2/AM is a membrane-permeable derivative of the calcium chelator FURA 2. Inside cells, FURA 2/AM is rapidly hydrolyzed by cytoplasmic esterases to FURA 2, which remains within the cell. Non-invasive,...
| Keywords: | FURA-2 acetoxymethyl ester, FURA-2 pentakis(acetoxymethyl) ester |
| Application: | Fluorescent probe, membrane-permeable calcium chelator |
| CAS | 108964-32-5 |
| MW: | 1001,87 D |
183.00€
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N-(3-Oxodecanoyl)-L-homoserine lactone
Item number: CDX-O0059-M010
White solid. Soluble in chloroform. N-(3-Oxodecanoyl)-DL-homoserine lactone is a small diffusible signaling molecule and is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) are involved in quorum sensing, controlling gene expression, and cellular metabolism. The diverse applications of...
| Keywords: | 3-oxo-C10-HSL, 3OC10-HSL, 3-oxo-N-[(3S)-Tetrahydro-2-oxo-3-furanyl]-decanamide |
| Application: | Quorum sensing, Gene expression control, Cellular metabolism |
| CAS | 147795-40-2 |
| MW: | 269,3 D |
From 77.00€
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7beta-Hydroxycholesterol
Item number: CDX-H0116-M005
White to white-yellow powder. Soluble in ethanol, chloroform or methanol. Oxysterole. Cholesterol oxidation metabolite. Induces cell death/apoptosis and shows antiproliferative activity against cancer cells, involving mitochondrial perturbation, oxidative stress and lysosomal destabilization. Its membrane organizing...
| Keywords: | 5-Cholestene-3beta,7beta-diol |
| Application: | Oxysterole, Cholesterol oxidation metabolite |
| CAS | 566-27-8 |
| MW: | 402,65 D |
From 183.00€
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4-(6-Methylbenzothiazol-2-yl)-aniline
Item number: CDX-M0119-G005
Solid. Soluble in chloroform. Building block for synthesis.
| Application: | Building block |
| CAS | 92-36-4 |
| MW: | 240,33 D |
From 168.00€
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3-Carboxy-6,8-difluoro-7-hydroxycoumarin
Item number: CDX-C0036-M025
Yellow powder. Soluble in chloroform. This amine-reactive reagent can be used to create blue-fluorescent bioconjugates with excitation/emission maxima ~410/455 nm that are excitable by the 405 nm spectral line of the blue diode (violet) laser. Used in highly sensitive analyses of amines, amino acids and dipeptides....
| Keywords: | NHS Pacific Blue succinimidyl ester, 2,5-Dioxopyrrolidin-1-yl 6,8-difluoro-7-hydroxy-2-oxo-2H-chromene-3-carboxylate |
| Application: | Amine-reactive blue-fluorescent bioconjugate reagent |
| CAS | 215868-33-0 |
| MW: | 339,2 D |
From 168.00€
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5-TAMRA
Item number: CDX-C0055-M025
Free acid form of 5-carboxytetramethylrhodamine single isomer. Widely used fluorophore for preparing bioconjugates, especially fluorescent antibody and avidin derivatives used in immunochemistry. Used as a dye for oligonucleotide labeling and automated DNA sequencing applications.
| Keywords: | 5-Carboxytetramethylrhodamine |
| Application: | Fluorescent dye |
| CAS | 91809-66-4 |
| MW: | 430,45 D |
From 183.00€
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Resorufin ethyl ether
Item number: CDX-R0013-M010
Solid. Soluble in alcohols, DMSO or DMF. Dealkylase substrate for the microfluorimetric analysis of microsomal cytochrome P-450.
| Keywords: | Ethoxyresorufin |
| Application: | Dealkylase substrate |
| CAS | 5725-91-7 |
| MW: | 241,24 D |
From 68.00€
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5-Fluorocytosine
Item number: CDX-F0077-G001
White to off-white powder. Soluble in water. Fluorinated pyrimidine analog. Antimycotic prodrug that is converted by cytosine deaminase to 5-fluorouracil (a widely used cytotoxic drug) and further metabolized to fluorinated ribo- and deoxyribonucleotides. Inhibits DNA and RNA synthesis and interfers with ribosomal...
| Keywords: | 4-Amino-5-fluoro-2(1H)-pyrimidinone, Flucytosine, NSC 103805, Ancotil, 5-FC, Ancobon, Ro 2-9915 |
| Application: | Antifungal, Antitumor |
| CAS | 2022-85-7 |
| MW: | 129,09 D |
From 183.00€
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Resorufin methyl ether
Item number: CDX-R0012-M010
Solid. Soluble in alcohols, DMSO or DMF. Substrate for Cytochrome P-450. Used for various investigations including the differentiatiation of cytochrome P-450 isozymes.
| Keywords: | Methoxyresorufin |
| Application: | Cytochrome P-450 substrate |
| CAS | 5725-89-3 |
| MW: | 227,22 D |
From 68.00€
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