Products from Cayman Chemical
Cayman Chemical Company, headquartered in Ann Arbor, Michigan, was founded in 1980 by Kirk Maxey, M.D. The company's goal is to help make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative stress, endocrinology, and many more. Cayman Chemical specializes in assay kits for the detection of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.
More information at: www.caymanchem.com
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Peroxynitrite
Item number: Cay81565-1
Peroxynitrite is formed in vivo by the reaction of NO with superoxide. It is a powerful oxidizing agent that can initiate lipid peroxidation, oxidize sulfhydryls, and nitrate the aromatic residues of proteins.Formal Name: peroxynitrous acid, sodium salt. CAS Number: 14042-01-4. Synonyms: Sodium Peroxynitrite....
| Keywords: | Sodium Peroxynitrite, peroxynitrous acid, sodium salt |
| Application: | Oxidizing agent |
| CAS | 14042-01-4 |
| MW: | 85 D |
101.00€
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Estradiol ELISA Kit
Item number: Cay501890-96
Estradiol is a steroid hormone produced from testosterone via the aromatase system in the granulosa cells of ovarian follicles. It is instrumental in the development of secondary sex characteristics at puberty and in the menstrual cycle. Plasma levels of estradiol peak during the follicular phase of the menstrual...
| Keywords: | 17beta-Estradiol, 17beta-Oestradiol, E2, Estradiol EIA Kit, beta-Estradiol |
| Application: | Competitive ELISA |
From 421.00€
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Chromomycin A3
Item number: Cay11315-5
Chromomycin A3 is an anthraquinone antibiotic and antitumor agent isolated from S. griseus that is used as a fluorescent probe for DNA with excitation/emission spectra of 445/575 nm. Its DNA binding is specific to two or more contiguous GC base pairs, which makes it suitable for characterizing heterochromatin in...
| Keywords: | Aburamycin B, CMA3, NSC 58514,... |
| Application: | FC, GC base pair fluorescent probe |
| CAS | 7059-24-7 |
| MW: | 1183.3 D |
From 80.00€
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(±)9-HODE
Item number: Cay38400-100
(±)9-HODE is one of the two racemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid. Approximately equal proportions of both isomers are found in mitochondrial and plasma membranes of rabbit reticulocytes. Oxidized LDL contains significant amounts of esterified 9- and 13-HpODEs...
| Keywords: | (±)-9-hydroxy-10E,12Z-octadecadienoic acid |
| Application: | Bioactive lipid studies |
| CAS | 98524-19-7 |
| MW: | 296.5 D |
From 223.00€
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Protein Carbonyl Colorimetric Assay Kit
Item number: Cay10005020-96
Cayman's Protein Carbonyl Colorimetric Assay Kit utilizes the DNPH reaction to measure the protein carbonyl content in plasma, serum, cell lysates, or tissue homogenates in a convenient 96-well format. The amount of protein-hydrozone produced is quantified spectrophotometrically at an absorbance between 360-385 nm....
| Application: | Oxidized protein quantification |
535.00€
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Resolvin D1
Item number: Cay10012554-10
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D1 (RvD1) is produced...
| Keywords: | 17(S)-Resolvin D1, RvD1, 7S,8R,17S-trihydroxy-4Z,9E,11E,13Z,15E,19Z-docosahexaenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 872993-05-0 |
| MW: | 376.5 D |
From 235.00€
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Arachidonic Acid-d8
Item number: Cay390010-1
Arachidonic acid-d8 is intended for use as an internal standard for the quantification of arachidonic acid (Cay-90010) by GC- or LC-MS. Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane...
| Keywords: | AA-d8, 5Z,8Z,11Z,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid |
| Application: | Standard |
| CAS | 69254-37-1 |
| MW: | 312.5 D |
From 198.00€
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Eicosapentaenoic Acid
Item number: Cay90110-50
EPA is an omega-3 fatty acid abundantly available in marine organisms. It is oxygenated by COX-1 and COX-2 at rates of about 5% and 30%, respectively, compared to arachidonic acid. EPA has been shown to offer protection against coronary heart disease, thrombosis, ischemic brain injury, scaly dermatitis, and some...
| Keywords: | EPA, Timnodonic Acid, 5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 10417-94-4 |
| MW: | 302.5 D |
From 59.00€
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DAPT
Item number: Cay13197-5
gamma-Secretase is a multi-subunit aspartyl protease that cleaves amyloid precursor protein (APP) and many other type 1 transmembrane proteins, including Notch, E-cadherin, and ErbB4. The proteolysis of APP by secretases produces beta amyloid (Abeta), a 39- to 42-amino acid peptide which forms the amyloid plaques...
| Keywords: | GSI-IX, N-[2S-(3,5-difluorophenyl)acetyl]-L-alanyl-2-phenyl-glycine, 1,1-dimethylethyl ester |
| Application: | gamma-secretase inhibitor |
| CAS | 208255-80-5 |
| MW: | 432.5 D |
From 91.00€
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8-iso Prostaglandin F2alpha
Item number: Cay16350-1
8-iso PGF2alpha is an isoprostane produced by the non-enzymatic peroxidation of arachidonic acid in membrane phospholipids. It is present in human plasma in two distinct forms - esterified in phospholipids and as the free acid. The ratio of these two forms is approximately 2:1, with a total plasma 8-iso PGF2alpha...
| Keywords: | 15-F2t-Isoprostane, 8-epi PGF2alpha, 8-iso-15(S)-Prostaglandin F2alpha, 8-Isoprostane, iPF2alpha-III,... |
| Application: | TP receptor agonist |
| CAS | 27415-26-5 |
| MW: | 354.5 D |
From 269.00€
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DPP (IV) Inhibitor Screening Assay Kit
Item number: Cay700210-96
DPP (IV) inhibitors have emerged as a new class of oral antidiabetic agents. These inhibitors promote glucose homeostasis by inhibiting degradation of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) by DPP (IV). GLP-1 extends the action of insulin while suppressing the release...
| Keywords: | Dipeptidyl peptidase IV |
| Application: | DPP (IV) inhibitor screening |
| Species reactivity: | human |
609.00€
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SU 5416
Item number: Cay13342-50
SU 5416 is a tyrosine kinase inhibitor best known as an inhibitor of the vascular endothelial growth factor receptor (VEGFR2, FLK1/KDR) and a suppressor of tumor vascularization, preventing the growth of multiple tumor types. In addition to inhibiting VEGFR2 (IC50 = 1 µM), SU 5416 also inhibits PDGFR (IC50 = 20 µM),...
| Keywords: | NSC 696819, Semaxinib, Sugen 5416, VEGFR 2 Kinase Inhibitor,... |
| Application: | Tyrosine kinase inhibitor |
| CAS | 204005-46-9 |
| MW: | 238.3 D |
From 198.00€
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