Products from Cayman Chemical
Cayman Chemical Company, headquartered in Ann Arbor, Michigan, was founded in 1980 by Kirk Maxey, M.D. The company's goal is to help make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative stress, endocrinology, and many more. Cayman Chemical specializes in assay kits for the detection of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.
More information at: www.caymanchem.com
No results were found for the filter!
PSB-KK1445
Item number: Cay42093-10
A GPR18 agonist, selective for GPR18 over GPR55 in beta-arrestin recruitment assays using CHO-K1 cells expressing the human receptors (EC50s = 0.0454 and >10 µM, respectively), does not bind to CB1 or CB2 receptors (Kis = >10 µM for both). Formulation: A solid. InChI:...
| Keywords: | 7-[(4-fluorophenyl)methyl]-3,7-dihydro-8-[[2-(1H-indol-3-yl)ethyl]amino]-1,3-dimethyl-1H-purine-2,6-dione |
| Application: | GPR18 agonist |
| CAS | 885896-54-8 |
| MW: | 446.5 D |
From 72.00€
*
K114
Item number: Cay34218-1
A fluorescent probe for the detection of amyloids, pH-dependent ex/em maxima = 370/450 nm, respectively, at pH 8.5, pH-dependent ex/em maxima = 420/520 nm, respectively, at pH 10.5, demonstrates increased fluorescence intensity in the presence of Aß40 fibrils, displays fiber-dependent excitation/emission maxima for...
| Keywords: | 4,4'-[(2-bromo-1,4-phenylene)di-(1E)-2,1-ethenediyl]bis-phenol |
| Application: | Fluorescent amyloid detection probe |
| CAS | 872201-12-2 |
| MW: | 393.27 D |
From 40.00€
*
I-OMe AG-538
Item number: Cay35090-1
An IGF-1R and PI5P4Ka inhibitor (IC50s = 3.4 and 1 µM, respectively), selectively cytotoxic to nutrient-deprived PANC-1 cells over nutrient-sufficient PANC-1 cells. Formulation: A solid. InChI: InChI=1S/C17H12INO5/c1-24-15-6-9(5-12(18)17(15)23)4-11(8-19)16(22)10-2-3-13(20)14(21)7-10/h2-7,20-21,23H,1H3/b11-4+....
| Keywords: | I-OMe Tyrphostin AG-538, 3,4-dihydroxy-aE-[(4-hydroxy-3-iodo-5-methoxyphenyl)methylene]-beta-oxo-benzenepropanenitrile |
| Application: | IGF-1R / PI5P4Ka inhibitor |
| CAS | 1094048-77-7 |
| MW: | 437.2 D |
From 45.00€
*
Doxycycline (hydrate)
Item number: Cay35830-1
A broad-spectrum tetracycline antibiotic, inhibits bacterial protein synthesis, selectively inhibits human MMP-8 and MMP-13 over MMP-1 with 50, 60, and 5% inhibition, respectively, at 30 µM, can be used as a regulator for inducible gene expression systems where expression depends on either the presence (Tet-On) or...
| Keywords: | (4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-... |
| Application: | Broad-spectrum tetracycline antibiotic |
| CAS | 17086-28-1 |
| MW: | 462.45 D |
From 40.00€
*
LNP GalNAc Ligand 1 (trifluoroacetate salt)
Item number: Cay38952-1
An ASGPR-targeting ligand, has been used in the formation of LNPs for the hepatic delivery of CRISPR base editors in mice. Formulation: A solid. InChI:...
| Keywords: | Lipid Nanoparticle GalNAc Ligand 1, Lipid Nanoparticle N-Acetylgalactosamine Ligand 1, LNP N-Acetylgalactosamine Ligand 1,... |
| Application: | ASGPR-targeting ligand |
| CAS | 1159408-65-7 |
| MW: | 1908 D |
From 70.00€
*
9alpha,10alpha-Epoxyhexahydrocannabinol
Item number: Cay39972-1
An analytical reference standard categorized as a phytocannabinoid metabolite, an active metabolite of Delta9-THC, induces catalepsy and hypothermia and enhances pentobarbital-induced sleep in mice, intended for research and forensic applications. Formulation: A solution in acetonitrile. InChI:...
| Keywords: | 1alpha,2alpha-Epoxyhexahydrocannabinol, 9alpha,10alpha-EHHC, 9alpha,10alpha-epoxy HHC,... |
| Application: | Analytical reference standard, phytocannabinoid metabolite |
| CAS | 56687-60-6 |
| MW: | 330.46 D |
From 95.00€
*
Palmitoyl-L-carnitine-d9 (chloride)
Item number: Cay40353-1
An internal standard for the quantification of palmitoyl-L-carnitine by GC- or LC-MS. Formulation: A solid. InChI: InChI=1S/C23H45NO4/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(27)28-21(19-22(25)26)20-24(2,3)4/h21H,5-20H2,1-4H3/t21-/m0/s1/i2D3,3D3,4D3. InChIKey: XOMRRQXKHMYMOC-UBNSAEOJSA-N. SMILES:...
| Keywords: | C16:0 Carnitine-d9, CAR 16:0-d9, Hexadecanoyl-L-carnitine-d9, L-Carnitine hexadecanoyl ester-d9, L-Carnitine palmitoyl... |
| Application: | GC-MS, LC-MS, internal standard, quantification |
| MW: | 445.12 D |
From 244.00€
*
Lirafugratinib
Item number: Cay40940-1
A covalent FGFR2 inhibitor (IC50 = 0.003 µM), selective for FGFR2 over FGFR1, -3, and -4 (IC50s = 0.77, 0.26, and 15 µM, respectively), inhibits the proliferation of SNU-16 cells (IC50 = 0.002 µM), reduces intratumoral FGFR2 phosphorylation and tumor volume in an FGFR2-amplified SNU-16 gastric cancer mouse xenograft...
| Keywords: | RLY-4008,... |
| Application: | Covalent FGFR2 inhibitor |
| CAS | 2549174-42-5 |
| MW: | 509.5 D |
From 55.00€
*
LGD 6972 (ammonium salt)
Item number: Cay40961-1
A GCGR antagonist, reduces glucagon-induced hyperglycemia in wild-type mice, reduces blood glucose levels in mouse models of diabetes. Formulation: A solid. InChI:...
| Keywords: | 2-[[4-[(2R)-2-[4'-(1,1-dimethylethyl)[1,1'-biphenyl]-4-yl]-3-oxo-3-[(2',4',6'-trimethyl[1,1'-biphenyl]-4-yl)amino]propyl]b... |
| Application: | GCGR antagonist |
| MW: | 719.9 D |
From 74.00€
*
CVN293
Item number: Cay40983-1
A K2P13.1/THIK1 channel inhibitor (IC50 = 49 nM), selective for K2P13.1/THIK1 over K2P6.1/TWIK2 and K2P2.1/TREK-1 channels (IC50s = >30,000 nM for both), inhibits NLRP3 inflammasome-mediated IL-1ß production in LPS-stimulated primary neonatal murine microglia (IC50 = 24 nM). Formulation: A solid. InChI:...
| Keywords: | 4-[7-fluoro-1-(3-pyridazinylmethyl)-1H-benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine |
| Application: | K2P13.1/THIK1 channel inhibitor |
| CAS | 2815296-08-1 |
| MW: | 311.27 D |
From 105.00€
*
Anti-Mertansine - Biotinylated
Item number: Cay41262-100
Immunogen: Mertansine-KLH conjugate Host: Rabbit Species Reactivity: Species-independent Cross Reactivity: (+) Mertansine-conjugated antibodies, (-) Albumin, VcMMAE-conjugated antibodies, unconjugated antibodies Applications: ELISA, WB. Formulation: 100 µg of biotinylated protein A-purified rabbit IgG....
| Keywords: | DM1, Drug Maytansinoid 1, Emtansine |
| Application: | ELISA, WB |
| Host: | Rabbit |
610.00€
*
ECC5004
Item number: Cay41324-1
A GLP-1R agonist, induces cAMP accumulation in HEK293 cells expressing human GLP-1R (EC50 = <20 nM). Formulation: A solid. InChI:...
| Keywords: | AZD 5004,... |
| Application: | GLP-1R agonist |
| CAS | 3011682-51-9 |
| MW: | 880.94 D |
299.00€
*