Products from Cayman Chemical
Cayman Chemical Company, headquartered in Ann Arbor, Michigan, was founded in 1980 by Kirk Maxey, M.D. The company's goal is to help make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative stress, endocrinology, and many more. Cayman Chemical specializes in assay kits for the detection of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.
More information at: www.caymanchem.com
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4-Amino-D-phenylalanine
Item number: Cay41971-1
A synthetic amino acid and building block, has been used in the synthesis of CXCR4 antagonists. Formulation: A solid. InChI: InChI=1S/C9H12N2O2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,10-11H2,(H,12,13)/t8-/m1/s1. InChIKey: CMUHFUGDYMFHEI-MRVPVSSYSA-N. SMILES: OC([C@H](N)CC1=CC=C(C=C1)N)=O
| Keywords: | 4-NH2-D-Phe, p-Amino-D-phenylalanine, para-Amino-D-phenylalanine, (R)-2-amino-3-(4-aminophenyl)propanoic acid |
| Application: | Synthetic amino acid, building block |
| CAS | 102281-45-8 |
| MW: | 180.2 D |
From 132.00€
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DOTA-NOC (acetate)
Item number: Cay41975-1
A synthetic peptide, has been conjugated to radioligands for use in PET imaging of neuroendocrine tumors and for tissue distribution studies in vivo. Formulation: A solid. InChI:...
| Keywords: | N-[2-[4,7,10-tris(carboxymethyl)-1,4,7,10-tetraazacyclododec-1-yl]acetyl]-D-phenylalanyl-L-cysteinyl-3-(1-naphthalenyl)-L-... |
| Application: | Synthetic peptide |
| MW: | 1455.7 D |
From 137.00€
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EM-12-FS
Item number: Cay41983-10
An NTAQ1 degrader, binds to CRBN (IC50 = 256 nM) and covalently labels His353, reduces the levels of NTAQ1 in MOLT-4 cells in a NEDDylation-dependent manner at 1 and 5 µM. Formulation: A solid. InChI:...
| Keywords: | 3-[6-[(fluorosulfonyl)oxy]-1,3-dihydro-1-oxo-2H-isoindol-2-yl]-2,6-piperidinedione |
| Application: | NTAQ1 degrader |
| CAS | 2839138-44-0 |
| MW: | 342.3 D |
From 137.00€
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KDS-0071
Item number: Cay41996-10
An imidazole-containing compound. Formulation: A solid. InChI: InChI=1S/C22H23FN4O3S/c23-18-12-16(6-7-17(18)13-26-8-10-31(29,30)11-9-26)19-2-1-3-21-24-20(14-27(19)21)25-22(28)15-4-5-15/h1-3,6-7,12,14-15H,4-5,8-11,13H2,(H,25,28). InChIKey: QDYVZZJCRDVVQG-UHFFFAOYSA-N. SMILES:...
| Keywords: | N-[5-[4-[(1,1-dioxido-4-thiomorpholinyl)methyl]-3-fluorophenyl]imidazo[1,2-a]pyridin-2-yl]-cyclopropanecarboxamide |
| Application: | Imidazole-containing compound, JAK1 inhibitor |
| CAS | 1973485-18-5 |
| MW: | 442.5 D |
From 60.00€
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WYneN
Item number: Cay42010-10
A chemoselective probe for protein sulfenylation, selective for sulfenylated proteins over DNTB and 4-DPS, binds to sulfenylated proteins in live cells and can then be conjugated to azide-containing fluorescent probes for detection. Formulation: A solid. InChI:...
| Keywords: | Wittig-alkyne N, [2-oxo-2-(2-propyn-1-ylamino)ethyl]triphenyl-phosphonium, monobromide |
| Application: | Chemoselective protein sulfenylation probe |
| CAS | 3052492-38-0 |
| MW: | 438.3 D |
From 153.00€
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8alpha,9alpha-epoxy Hexahydrocannabinol
Item number: Cay42021-1
An analytical reference standard categorized as a phytocannabinoid metabolite, a metabolite of Delta8-THC, intended for research and forensic applications. Formulation: A solution in acetonitrile. InChI:...
| Keywords: | 8alpha,9alpha-EEHC, 8alpha,9alpha-epoxy HHC,... |
| Application: | Analytical reference standard, phytocannabinoid metabolite |
| CAS | 80513-76-4 |
| MW: | 330.5 D |
From 95.00€
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PCsBu (hydrochloride)
Item number: Cay42031-1
An analytical reference standard categorized as an arylcyclohexylamine, intended for research and forensic applications. Formulation: A solid. InChI: InChI=1S/C16H25N.ClH/c1-3-14(2)17-16(12-8-5-9-13-16)15-10-6-4-7-11-15,/h4,6-7,10-11,14,17H,3,5,8-9,12-13H2,1-2H3,1H. InChIKey: SHCLNWOHLQKXRR-UHFFFAOYSA-N. SMILES:...
| Keywords: | PCsBuA, N-(1-methylpropyl)-1-phenyl-cyclohexanamine, monohydrochloride |
| Application: | Analytical reference standard, arylcyclohexylamine |
| CAS | 18949-88-7 |
| MW: | 267.84 D |
From 126.00€
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Metapramine
Item number: Cay42033-1
An antidepressant, decreases action potential amplitude and maximal signal velocity and increases conduction time in isolated dog Purkinje fibers at 10 µM, reduces ethanol consumption in ethanol-preferring rats at 10 mg/kg, inhibits reperfusion-induced increases in ventricular arrhythmias in a rat model of...
| Keywords: | RP 19560, 10,11-dihydro-N,5-dimethyl-5H-dibenz[b,f]azepin-10-amine |
| Application: | Antidepressant |
| CAS | 21730-16-5 |
| MW: | 238.3 D |
From 40.00€
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MitoBloCK-10
Item number: Cay42054-1
A mitochondrial protein import inhibitor, inhibits the import of cytochrome c1 into the mitochondrial intermembrane space in yeast cells at 100 µM, inhibits migration and invasion of, and induces apoptosis and cell cycle arrest at the G1 phase in, primary human bladder cancer cells at 25 µM, induces mitochondrial...
| Keywords: | MB-10, 3-fluoro-benzoic acid 2-[(5-nitro-2-thienyl)methylene]hydrazide |
| Application: | Mitochondrial protein import inhibitor |
| CAS | 394694-98-5 |
| MW: | 293.27 D |
From 40.00€
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MCUF-651
Item number: Cay42055-10
A GC-A positive allosteric modulator, induces the production of cGMP in the presence (EC50 = 0.45 µM) but not the absence of ANP in HEK293 cells expressing human GC-A, selective for GC-A over GC-B in HEK293 cells expressing the human receptors at 10 µM, binds to the GC-A extracellular domain (Kd = 397 nM) and...
| Keywords: | N-(4,6-difluoro-2-benzothiazolyl)-1-[2-(dimethylamino)ethyl]-3-piperidinecarboxamide |
| Application: | GC-A positive allosteric modulator |
| CAS | 2747162-85-0 |
| MW: | 368.45 D |
From 193.00€
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SB-505124 (hydrochloride)
Item number: Cay42056-1
An ALK5 and ALK4 inhibitor (IC50s = 47 and 129 nM, respectively), selective for ALK5 and ALK4 over a panel of 27 kinases at 10 µM, inhibits ALK7-induced increases in phosphorylated SMAD2 levels in COS-1 cells overexpressing ALK7 at 5 µM, inhibits TGF-beta-induced but not TNF-alpha-induced apoptosis in Fao cells at 1...
| Keywords: | TGF-beta Receptor Type I Kinase Inhibitor III, TGF-beta RI Kinase Inhibitor III,... |
| Application: | ALK5 / ALK4 inhibitor |
| CAS | 356559-13-2 |
| MW: | 371.9 D |
From 40.00€
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PVP-037
Item number: Cay42073-1
A TLR7/8 agonist adjuvant, induces the production of other cytokines and chemokines, including TNF, IFN-gamma, IL-1ß, and IL-6, in primary human PBMCs at =1 µM, increases anti-rHA IgG titers in mice when used as an adjuvant to rHA. Formulation: A solid. InChI:...
| Keywords: | a-ethyl-N-(5-imidazo[1,2-a]pyrimidin-2-yl-2-methylphenyl)-benzeneacetamide |
| Application: | TLR7/8 agonist adjuvant |
| CAS | 862810-50-2 |
| MW: | 370.5 D |
From 91.00€
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