Products from Cayman Chemical
Cayman Chemical Company, headquartered in Ann Arbor, Michigan, was founded in 1980 by Kirk Maxey, M.D. The company's goal is to help make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative stress, endocrinology, and many more. Cayman Chemical specializes in assay kits for the detection of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.
More information at: www.caymanchem.com
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GAPDH Inhibitor Compound F8
Item number: Cay42090-1
A covalent inhibitor of GAPDH (IC50 = 39.31 µM), decreases viability of, and glucose metabolism in, HEK293 cells in a concentration-dependent manner. Formulation: A solid. InChI: InChI=1S/C20H18N2O5/c1-3-13(7-15(5-1)23-9-17-11-25-17)19-21-22-20(27-19)14-4-2-6-16(8-14)24-10-18-12-26-18/h1-8,17-18H,9-12H2. InChIKey:...
| Keywords: | 2,5-bis[3-(2-oxiranylmethoxy)phenyl]-1,3,4-oxadiazole |
| Application: | GAPDH covalent inhibitor |
| CAS | 252212-58-1 |
| MW: | 366.37 D |
From 55.00€
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Martinostat
Item number: Cay42100-10
An HDAC inhibitor (IC50s = 0.3, 2, 0.6, and 4.1 nM for HDAC1, -2, -3, and -6, respectively), selective for these HDACs over HDAC4, -5, -7, -8, and -9 (IC50s = 1,970, 352, >20,000, >15,000, and >15,000 nM, respectively), reduces H3K9ac and H4K12ac in primary mouse neuronal cells (EC50s = 100 nM for both)....
| Keywords: | N-hydroxy-3-[4-[[methyl(tricyclo[3.3.1.13,7]dec-1-ylmethyl)amino]methyl]phenyl]-2E-propenamide |
| Application: | HDAC inhibitor |
| CAS | 1629052-58-9 |
| MW: | 354.5 D |
From 153.00€
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GSK467
Item number: Cay42103-1
A JARID1B inhibitor (IC50 = 0.02-0.1 µM), selective for JARID1B over KMD2, -3, -4, and -5 (IC50s = 1-10 µM). Formulation: A solid. InChI: InChI=1S/C17H13N5O2/c23-16-14-6-7-18-9-15(14)20-17(21-16)24-13-8-19-22(11-13)10-12-4-2-1-3-5-12/h1-9,11H,10H2,(H,20,21,23). InChIKey: ZTYRLXUTLYBVHH-UHFFFAOYSA-N. SMILES:...
| Keywords: | 2-[[1-(phenylmethyl)-1H-pyrazol-4-yl]oxy]- pyrido[3,4-d]pyrimidin-4(3H)-one |
| Application: | JARID1B (KDM5B) inhibitor |
| CAS | 1628332-52-4 |
| MW: | 319.3 D |
From 60.00€
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GSK3beta Inhibitor 1
Item number: Cay42107-10
A GSK3beta inhibitor (IC50 = 4.19 nM), decreases blood glucose levels in an OGTT in a rat model of high-fat diet and STZ-induced diabetes at 50 mg/kg. Formulation: A solid. InChI: InChI=1S/C14H10N2O/c17-14-12(9-10-5-3-4-8-15-10)11-6-1-2-7-13(11)16-14/h1-9H,(H,16,17)/b12-9-. InChIKey: YKQONSWBHGBDSB-XFXZXTDPSA-N....
| Keywords: | Glycogen Synthase Kinase 3beta Inhibitor I, (3Z)-1,3-dihydro-3-(2-pyridinylmethylene)-2H-indol-2-one |
| Application: | GSK3beta inhibitor |
| CAS | 187325-53-7 |
| MW: | 222.2 D |
From 223.00€
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A-425619
Item number: Cay42117-10
A TRPV1 antagonist, selective for TRPV1 over a panel of 83 receptors, enzymes, transporters, and ion channels at 10 µM, inhibits capsaicin-, NADA-, anandamide-, or acid-induced increases in intracellular calcium in HEK293 cells expressing human TRPV1 (IC50s = 5, 4, 3, and 2 nM, respectively), increases core body...
| Keywords: | N-5-isoquinolinyl-N'-[[4-(trifluoromethyl)phenyl]methyl]-urea |
| Application: | TRPV1 antagonist |
| CAS | 581809-67-8 |
| MW: | 345.3 D |
From 208.00€
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D-Amino Acid Oxidase Inhibitor
Item number: Cay23894-100
An inhibitor of DAAO (IC50s = 145 and 114 nM in CHO cells expressing human and rat DAAO, respectively), selective for DAAO over a panel of 150 enzymes, receptors and ion channels (30 µM), inhibits DAAO activity in rat kidney and cerebellum in a dose- and time-dependent manner (10-200 mg/kg, i.p.), increases levels...
| Keywords: | DAAO inhibitor, 4H-thieno[3,2-b]pyrrole-5-carboxylic acid |
| Application: | DAAO inhibitor |
| CAS | 39793-31-2 |
| MW: | 167.2 D |
From 40.00€
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Voacanga africana Ethanol Extract
Item number: Cay43250-1
A natural extract, contains a crude mixture of bioactive natural products extracted from V. africana. Formulation: A solution in methanol. InChI: . InChIKey: . SMILES:
| Keywords: | V. africana Ethanol Extract |
| Application: | Natural extract, crude mixture of bioactive natural products |
76.00€
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BSA-Stearate Saturated Fatty Acid Complex (0.34 mM)
Item number: Cay43451-5
A fatty acid substrate, can be used for efficient fatty acid delivery to cells in culture for monitoring fatty acid oxidation or similar processes in various cellular metabolic studies. Formulation: 0.34 mM Stearate:0.17 mM BSA in 150 mM sodium chloride. InChI: . InChIKey: . SMILES:
| Keywords: | Bovine Serum Albumin-SA, Bovine Serum Albumin-Stearate, BSA-SA |
| Application: | Fatty acid substrate, efficient fatty acid delivery, cell culture |
| Expressed in: | Bovine |
274.00€
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HRP Development Pack
Item number: Cay502870-1
Contains a high-sensitivity and low-background substrate and stop solution for use with HRP-based ELISAs. Formulation: . InChI: . InChIKey: . SMILES:
| Application: | HRP-based ELISA high-sensitivity / low-background substrates, stop solution |
From 132.00€
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BSA-Docosahexaenoate-d5 Polyunsaturated Fatty Acid...
Item number: Cay43591-5
A fatty acid substrate, can be used for efficient fatty acid delivery to cells in culture for the purpose of monitoring fatty acid oxidation or similar processes in various cellular metabolic studies. Formulation: 1 mM Docosahexanoate-d5:0.17 mM BSA (6:1 docosahexanoate-d5:BSA) in 150 mM sodium chloride, pH 7.4....
| Keywords: | Bovine Serum Albumin-Docosahexaenoate-d5, BSA-DHA-d5 |
| Application: | Fatty acid substrate, efficient fatty acid delivery, cell culture |
| Expressed in: | Bovine |
254.00€
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Firefly Luciferase mRNA (Cap-1, m1Psi)
Item number: Cay43677-1
An mRNA for the expression of luciferase, encapsulation in LNPs can be used for mRNA delivery and expression of luciferase. Formulation: 1 mM Sodium citrate, pH 6.4. InChI: . InChIKey: . SMILES:
| Keywords: | Luciferase, Luciferin 4-monooxygenase |
| Application: | mRNA expression |
From 701.00€
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