Products from Cayman Chemical
Cayman Chemical Company, headquartered in Ann Arbor, Michigan, was founded in 1980 by Kirk Maxey, M.D. The company's goal is to help make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative stress, endocrinology, and many more. Cayman Chemical specializes in assay kits for the detection of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.
More information at: www.caymanchem.com
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GSK3685032
Item number: Cay41882-1
A DNMT1 inhibitor (IC50 = 0.23 µM), selective for DNMT1 over DNMT3A/3L and DNMT3B/3L and a panel of 34 methyltransferases and 369 kinases (IC50s = >10 µM for all), inhibits the proliferation of 51 hematological cancer cell lines (median IC50 = 0.64 µM), decreases overall DNA methylation and gene expression in...
| Keywords: | aR-[[6-(4-amino-1-piperidinyl)-3,5-dicyano-4-ethyl-2-pyridinyl]thio]-benzeneacetamide |
| Application: | DNMT1 inhibitor |
| CAS | 2170140-50-6 |
| MW: | 420.54 D |
From 104.00€
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Santalol
Item number: Cay41891-100
A mixture of alpha-santalol and beta-santalol. Formulation: A neat oil. InChI: InChI=1S/2C15H24O/c1-10(9-16)5-4-6-14(2)11-7-12-13(8-11)15(12,14)3,1-11(10-16)5-4-8-15(3)12(2)13-6-7-14(15)9-13/h5,11-13,16H,4,6-9H2,1-3H3,5,13-14,16H,2,4,6-10H2,1,3H3/b10-5-,11-5-/t11?,12-,13?,14+,15?,13-,14+,15+/m01/s1. InChIKey:...
| Application: | Sesquiterpenoids, alpha-santalol/beta-santalol mixture |
| CAS | 11031-45-1 |
| MW: | 220.4 D |
From 45.00€
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BH400
Item number: Cay41892-1
A PPARalpha agonist and STING inhibitor (IC50 = 8.1 µM), induces transactivation of PPARalpha in a reporter assay using THP-1 cells (EC50 = 1.2 µM), inhibits 4-HNE- or H2O2-induced decreases in viability in 661W cells at 10 µM, prevents LPS-induced increases in phosphorylated TBK1 and IL-6 levels and LPS-induced...
| Keywords: | 5-(((4'-fluoro-[1,1'-biphenyl]-4-yl)methyl)amino)-2-hydroxybenzoic acid |
| Application: | PPARalpha agonist, STING inhibitor |
| MW: | 337.4 D |
From 116.00€
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DBCO-amine
Item number: Cay41895-100
A copper-free click chemistry reagent, has been used in the synthesis of clickable fluorescent probes. Formulation: A solid. InChI: InChI=1S/C18H16N2O/c19-12-11-18(21)20-13-16-7-2-1-5-14(16)9-10-15-6-3-4-8-17(15)20/h1-8H,11-13,19H2. InChIKey: OCCYFTDHSHTFER-UHFFFAOYSA-N. SMILES: O=C(CCN)N1CC2=C(C#CC3=C1C=CC=C3)C=CC=C2
| Keywords: | Dibenzylcyclooctyne-amine, 3-amino-1-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-1-propanone |
| Application: | Copper-free click chemistry reagent |
| CAS | 1255942-06-3 |
| MW: | 276.3 D |
From 130.00€
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DSPE-PEG(2000)-Biotin
Item number: Cay41914-10
A PEGylated and biotinylated form of DPSE, has been used in the generation of liposomes for the delivery of small molecules in vitro and in vivo, has been used in the formation of micelles as a precursor to immobilized liposomes for biolayer interferometry binding assays, liposomes containing DSPE-PEG(2000)-biotin...
| Keywords: | 1,2-Distearoyl-sn-glycero-3-PE-Polyethylene Glycol-2000-Biotin,... |
| Application: | PEGylated / biotinylated DPSE |
From 151.00€
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C8 Ceramide-mPEG(2000)
Item number: Cay41954-1
A PEGylated form of C8 ceramide, has been used in the generation of lipoplexes and lipid particles for the delivery of plasmid DNA and siRNA in vitro and in vivo, lipid particles encapsulating plasmid DNA and containing C8 MPEG(2000) ceramide have a higher transfection efficiency than those containing C14- or C20...
| Keywords: | Capryl Ceramide Methoxy Polyethylene Glycol-2000, N-Capryl-D-erythro-Sphingosine mPEG(2000),... |
| Application: | PEGylated C8 ceramide |
| CAS | 212116-76-2 |
From 411.00€
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C16 Ceramide-mPEG(2000)
Item number: Cay41955-1
A PEGylated form of C16 ceramide, has been used in the generation of microspheres, LNPs, and liposomes for the delivery of small molecules, mRNA, and plasmid DNA in vitro and in vivo, liposomes containing C16 ceramide-mPEG(2000) with a stearylated-INF7 and have been used to transfect plasmid DNA into MFLM-4 cells,...
| Keywords: | Cer(d18:1/16:0) MPEG(2000), MPEG(2000) Ceramide (d18:1/16:0), N-Hexadecanoyl-D-erythro-Sphingosine mPEG(2000),... |
| Application: | PEGylated C16 ceramide PEGylated form |
| CAS | 212116-78-4 |
From 74.00€
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DL-Cysteine
Item number: Cay41968-1
A racemic mixture of D- and L-cysteine, prevents reserpine- and pyloric stenosis-induced gastric ulceration in rats at 5% w/v, improves motility and DNA integrity in frozen and thawed epididymal spermatozoa from cats in cryoprotectants at 5 mM. Formulation: A solid. InChI:...
| Keywords: | (±)-Cysteine, (R,S)-Cysteine, NSC 63864 |
| Application: | D-/L-cysteine racemic mixture |
| CAS | 3374-22-9 |
| MW: | 121.16 D |
From 40.00€
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Fmoc-beta-Alanine
Item number: Cay41969-10
A building block, has been used in the solid-phase synthesis of glucagon receptor peptide antagonists and bradykinin B1 and B2 receptor pseudopeptide antagonists. Formulation: A solid. InChI: InChI=1S/C18H17NO4/c20-17(21)9-10-19-18(22)23-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2,(H,19,22)(H,20,21)....
| Keywords: | Fmoc-beta-Ala-OH, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-beta-alanine |
| Application: | Building block |
| CAS | 35737-10-1 |
| MW: | 311.33 D |
From 40.00€
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Coumarin 343
Item number: Cay41970-100
A coumarin laser dye, abs/em = 446/519 nm. Formulation: A solid. InChI: InChI=1S/C16H15NO4/c18-15(19)12-8-10-7-9-3-1-5-17-6-2-4-11(13(9)17)14(10)21-16(12)20/h7-8H,1-6H2,(H,18,19). InChIKey: KCDCNGXPPGQERR-UHFFFAOYSA-N. SMILES: O=C(C1=CC2=C(OC1=O)C(CCCN3CCC4)=C3C4=C2)O
| Keywords: | 2,3,6,7-tetrahydro-11-oxo-1H,5H,11H-[1]benzopyrano[6,7,8-ij]quinolizine-10-carboxylic acid |
| Application: | Coumarin laser dye |
| CAS | 55804-65-4 |
| MW: | 285.29 D |
From 55.00€
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ARV-766
Item number: Cay41985-1
A PROTAC that drives androgen receptor degradation (DC50 = <1 nM), inhibits tumor growth in various LNCaP and VCaP prostate cancer mouse xenograft models, including an enzalutamide-insensitive, non-castrated VCaP model. Formulation: A solid. InChI:...
| Keywords: | Luxdegalutamide,... |
| Application: | Androgen receptor degradation driving PROTAC |
| CAS | 2750830-09-0 |
| MW: | 807.95 D |
From 119.00€
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8beta,9beta-epoxy Hexahydrocannabinol
Item number: Cay42022-1
An analytical reference standard categorized as a phytocannabinoid metabolite, an active metabolite of Delta8-THC, prolongs pentobarbital-induced sleeping time in mice, intended for research and forensic applications. Formulation: A solution in acetonitrile. InChI:...
| Keywords: | 8beta,9beta-EHHC, 8beta,9beta-epoxy HHC,... |
| Application: | Analytical reference standard, phytocannabinoid metabolite |
| CAS | 64783-83-1 |
| MW: | 330.46 D |
From 95.00€
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