Products from Cayman Chemical

Cayman

Cayman Chemical Company, headquartered in Ann Arbor, Michigan, was founded in 1980 by Kirk Maxey, M.D. The company's goal is to help make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative stress, endocrinology, and many more. Cayman Chemical specializes in assay kits for the detection of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.

More information at: www.caymanchem.com

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2235 from 2238 pages
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Erdosteine
Erdosteine

Item number: Cay29177-500

Erdosteine is a mucolytic agent and an antioxidant. It inhibits LPS-induced IkappaB kinase (IKK) activity, NF-kappaB-mediated transcription, and production of IL-6 and IL-1beta in RAW 264.7 cells. Erdosteine (7.5 mg/kg) prevents depletion of renal catalase and glutathione peroxidase (GPX) and increases in renal...
Keywords: Erdostin, 2-[[2-oxo-2-[(tetrahydro-2-oxo-3-thienyl)amino]ethyl]thio]-acetic acid
Application: Mucolytic agent, antioxidant
CAS 84611-23-4
MW: 249.3 D
120.00€ *
Review
M2 Peptide
M2 Peptide

Item number: Cay40263-1

M2 peptide is an M2 tumor-associated macrophage-targeting peptide. It has been used in the generation of anticancer polymeric micelles encapsulating the STAT6 inhibitor AS1517499 (Cay-29071) for delivery to M2 tumor-associated macrophages (TAMs) in vitro and in vivo. Cayman's M2 Peptide is intended for use in...
Keywords: M2pep, TAM-targeting Peptide
Application: M2 TAM-targeting peptide, drug delivery
458.00€ *
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SARS-CoV-2 nsp1 (recombinant)
SARS-CoV-2 nsp1 (recombinant)

Item number: Cay40879-100

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped positive-stranded RNA virus and the causative agent of COVID-19, a primarily respiratory illness characterized by fever, cough, and shortness of breath that can lead to life-threatening complications. The SARS-CoV-2 genome contains...
Keywords: rep, GFL, Pol, Hel, nsp1, nsp2, nsp3, nsp4, 3CLp, Mpro, nsp5, nsp6, nsp7, nsp8, nsp9, RdRp, ExoN, 1a-1b, pp1ab, nsp10,...
Expressed in: E.coli
Origin: SARS-CoV-2
From 835.00€ *
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SARS-CoV-2 nsp4 (recombinant)
SARS-CoV-2 nsp4 (recombinant)

Item number: Cay40880-100

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped positive-stranded RNA virus, a member of the Betacoronavirus genus, and the causative agent of COVID-19. The SARS-CoV-2 genome contains approximately 30 kilobases and 14 open reading frames (ORFs) that encode four structural proteins:...
Keywords: rep, GFL, Pol, Hel, nsp1, nsp2, nsp3, nsp4, 3CLp, Mpro, nsp5, nsp6, nsp7, nsp8, nsp9, RdRp, ExoN, 1a-1b, pp1ab, nsp10,...
Expressed in: E.coli
Origin: SARS-CoV-2
From 835.00€ *
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SARS-CoV-2 nsp8 (recombinant)
SARS-CoV-2 nsp8 (recombinant)

Item number: Cay40882-100

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped positive-stranded RNA virus and the causative agent of COVID-19, a primarily respiratory illness characterized by fever, cough, and shortness of breath that can lead to life-threatening complications. The SARS-CoV-2 genome contains...
Keywords: rep, GFL, Pol, Hel, nsp1, nsp2, nsp3, nsp4, 3CLp, Mpro, nsp5, nsp6, nsp7, nsp8, nsp9, RdRp, ExoN, 1a-1b, pp1ab, nsp10,...
Expressed in: E.coli
Origin: SARS-CoV-2
From 835.00€ *
Review
Afatinib (maleate)
Afatinib (maleate)

Item number: Cay21567-100

Afatinib is an irreversible inhibitor of epidermal growth factor receptor (EGFR) and ErbB2 (IC50s = 0.5 and 14 nM, respectively). It increases the cytotoxicity of adriamycin in a concentration-dependent manner in multidrug-resistant A549T lung cancer cells overexpressing P-glycoprotein. Afatinib (20 mg/kg) reduces...
Keywords: Afatinib dimaleate, BIBW 2992, BIBW 2992MA2,...
Application: EGFR / ERBB2 / ERBB4 inhibitor
CAS 850140-73-7
MW: 718.1 D
76.00€ *
Review
1-Palmitoyl-d9-2-Palmitoyl-sn-glycero-3-PC
1-Palmitoyl-d9-2-Palmitoyl-sn-glycero-3-PC

Item number: Cay28154-100

1-Palmitoyl-d9-2-palmitoyl-sn-glycero-3-PC is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PC (Cay-10009473) by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PC (DPPC) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers,...
Keywords: 16:0-d9/16:0-PC, 1-Hexadecanoyl-d9-2-Hexadecanoyl-sn-glycero-3-Phosphatidylcholine,...
Application: GC-MS, LC-MS, internal standard, quantification
MW: 743.1 D
From 76.00€ *
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1-Palmitoyl-d9-2-Palmitoyl-sn-glycero-3-PE
1-Palmitoyl-d9-2-Palmitoyl-sn-glycero-3-PE

Item number: Cay28155-100

1-Palmitoyl-d9-2-palmitoyl-sn-glycero-3-PE is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PE (Cay-15092) by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) is a naturally occurring PE containing C16:0 fatty acids at the sn-1 and sn-2 positions. It belongs...
Keywords: 16:0-d9/16:0-PE, 1-Hexadecanoyl-d9-2-Hexadecanoyl-sn-glycero-3-Phosphatidylethanolamine,...
Application: GC-MS, LC-MS, internal standard, quantification
CAS 2747990-85-6
MW: 701 D
91.00€ *
Review
Ganoderic Acid C2
Ganoderic Acid C2

Item number: Cay30371-500

Ganoderic acid C2 is a triterpene that has been found in G. lucidum. It inhibits histamine release from isolated rat mast cells induced by concanavalin A (Cay-14951) or compound 48/80 (Cay-22173) when used at a concentration of 2 mg/ml.Formal Name: 3beta,7,15alpha-trihydroxy-11,23-dioxo-lanost-8-en-26-oic acid. CAS...
Keywords: 3beta,7,15alpha-trihydroxy-11,23-dioxo-lanost-8-en-26-oic acid
Application: Triterpene
CAS 98296-48-1
MW: 518.7 D
123.00€ *
Review
MPEG(30000)-NHS ester
MPEG(30000)-NHS ester

Item number: Cay39743-100

MPEG(30000)-NHS ester is a PEGylated and esterified form of N-hydroxysuccinimide (NHS).Formal Name: 2,5-dioxopyrrolidin-1-yl 2-(2-methoxyethoxy)acetate. Synonyms: Methoxy Polyethylene Glycol-30000-NHS ester, MPEG30000-NHS ester. Molecular Formula: (C2H4O)nC7H9NO5. Purity: >90%. Formulation: (Request formulation...
Keywords: Methoxy Polyethylene Glycol-30000-NHS ester, MPEG30000-NHS ester, 2,5-dioxopyrrolidin-1-yl 2-(2-methoxyethoxy)acetate
Application: PEGylated, esterified NHS
153.00€ *
Review
C6 Ceramide (d18:1/6:0) Alkyne
C6 Ceramide (d18:1/6:0) Alkyne

Item number: Cay24519-100

C6 Ceramide alkyne is an omega-alkyne derivative of C6 ceramide (Cay-62525). The terminal alkyne group can be used in click chemistry reactions to tag C6 ceramide with fluorescent or biotinylated labels for analysis of its metabolism and biological activity.Formal Name:...
Keywords: C6 Ceramide Alkyne, Cer(d18:1/6:0) Alkyne, Click Tag(TM) C6 Ceramide (d18:1/6:0) Alkyn, N-hexanoyl-D-erythro-Sphingosine...
Application: omega-alkyne, click chemistry
MW: 393.6 D
51.00€ *
Review
TAF 10 Peptide
TAF 10 Peptide

Item number: Cay10228-1

TAF10 is one of many protein factors or coactivators associated with RNA polymerase II activity. One vial of this peptide may be used as a methyltransferase acceptor peptide for more than 200 reactions at 15 µM.Synonyms: TAF10 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, TBP-Associated Factor...
Keywords: TAF10 RNA Polymerase II, TAFII30, TATA Box Binding Protein (TBP)-Associated Factor, TBP-Associated Factor 10
Application: Methyltransferase acceptor
MW: 1267 D
502.00€ *
Review
2235 from 2238 pages