Products from Cayman Chemical
Cayman Chemical Company, headquartered in Ann Arbor, Michigan, was founded in 1980 by Kirk Maxey, M.D. The company's goal is to help make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative stress, endocrinology, and many more. Cayman Chemical specializes in assay kits for the detection of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.
More information at: www.caymanchem.com
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Anti-Citrullinated Collagen Type II (Fc Silent) (Clone...
Item number: Cay39296-200
Collagen type II is a fibril-forming heterodimeric protein present in cartilage, cartilaginous zones of tendons, and intervertebral discs that is subject to citrullination by peptidyl arginine deiminase 2 (PAD2) and PAD4. Citrullinated collagen type II and autoantibodies to citrullinated collagen type II have been...
| Keywords: | Anti-citrullinated-Alpha-1 type II collagen, Anti-citrullinated--Collagen alpha-1(II) chain, Anti-citrullinated-Collagen... |
| Application: | ELISA, IHC |
| Host: | Mouse |
657.00€
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Anti-Citrullinated Collagen Type II Chimeric Rabbit...
Item number: Cay39297-200
Collagen type II is a fibril-forming heterodimeric protein present in cartilage, cartilaginous zones of tendons, and intervertebral discs that is subject to citrullination by peptidyl arginine deiminase 2 (PAD2) and PAD4. Citrullinated collagen type II and autoantibodies to citrullinated collagen type II have been...
| Keywords: | Anti-Alpha-1 type II collagen, Anti-Collagen alpha-1(II) chain, Anti-Collagen alpha-1(II) chain, Anti-Chondrocalcin,... |
| Application: | ELISA, IHC |
| Host: | Rabbit/Mouse |
| Species reactivity: | bovine, human |
657.00€
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Anti-Citrullinated Collagen Type II (Clone ACC1)
Item number: Cay39295-200
Collagen type II is a fibril-forming heterodimeric protein present in cartilage, cartilaginous zones of tendons, and intervertebral discs that is subject to citrullination by peptidyl arginine deiminase 2 (PAD2) and PAD4. Citrullinated collagen type II and autoantibodies to citrullinated collagen type II have been...
| Keywords: | Alpha-1 Type II Collagen, Collagen Alpha-1(II) Chain, Citrullinated Collagen Type II Monoclonal Antibody (Clone ACC1) |
| Application: | ELISA, IHC |
| Host: | Mouse |
| Species reactivity: | bovine, human |
610.00€
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(E/Z)-Belinostat
Item number: Cay10004279-10
(E/Z)-Belinostat is a racemic form of the class I and II histone deacetylase (HDAC) inhibitor belinostat (Cay-34084).Formal Name: N-hydroxy-3-[3-[(phenylamino)sulfonyl]phenyl]-2-propenamide. CAS Number: 414864-00-9. Synonyms: (E/Z)-PXD 101, (E/Z)-PX 105684. Molecular Formula: C15H14N2O4S. Formula Weight: 318.3....
| Keywords: | (E/Z)-PX 105684, (E/Z)-PXD 101, N-hydroxy-3-[3-[(phenylamino)sulfonyl]phenyl]-2-propenamide |
| Application: | Belinostat (class I/II histone deacetylase (HDAC) inhibitor), racemic |
| CAS | 414864-00-9 |
| MW: | 318.3 D |
From 54.00€
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AAA
Item number: Cay32733-500
AAA is an antagonist of G protein-coupled receptor 75 (GPR75). It increases basal GPR75 protein levels and inhibits 20-HETE-induced reductions in GPR75 protein levels in PC3 cells. AAA (5 and 10 µM) also reduces 20-HETE-induced phosphorylation of EGFR, NF-kappaB, and Akt in, and cell migration of, PC3 cells. In...
| Keywords: | (20-hydroxyicosa-6Z,15Z-dienoyl)aspartate, disodium salt |
| Application: | GPR75 antagonist |
| MW: | 483.5 D |
197.00€
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SET7/9 Methyltransferase Inhibitor Screening Assay Kit
Item number: Cay700270-96
SET7/9 is an MT that acts on various substrates including histone 3 at lysine residue 4 (H3K4), p53, and the transcription factor TAF 10. In Cayman's SET7/9 MT Inhibitor Screening Assay the transfer of the methyl group from SAM by SET7/9 to the acceptor peptide (TAF 10) generates SAH, which is rapidly converted to...
| Keywords: | KMT7, SET Domain-containing Protein 7/9, SETD7/9 |
| Application: | Inhibitor screening |
| Species reactivity: | human |
1,146.00€
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SET8 Methyltransferase Inhibitor Screening Assay Kit
Item number: Cay700350-96
SET Domain-containing Protein 8 (SET8) is a methyltransferase that selectively mono-methylates histone H4 at lysine residue 20 (H4K20), an event proven to have an important role in chromatin structure and transcriptional activation. Cayman's SET8 Methyltransferase Inhibitor Screening Assay provides a convenient...
| Keywords: | PR-Set7, SET domain-containing (lysine methyltransferase) 8, SETD8 |
| Application: | SET8 inhibitor screening |
1,146.00€
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Docetaxel Polymeric Nanoparticles
Item number: Cay39769-2
Docetaxel polymeric nanoparticles (PNPs) are nanoparticles composed of tocofersolan (TPGS, Cay-34661), poloxanlene, trehalose (Cay-20517), and TBS that encapsulate docetaxel (Cay-11637) and are 15 to 20 nm in size as determined by dynamic light scattering (DLS). PNP formulations are a lipid-based drug delivery...
| Keywords: | Docetaxel PNPs, Docetaxel Polymer-based Nanoparticles, DTX PNPs, RP 56976 PNPs |
| Application: | Docetaxel-based PNP formulation |
1,068.00€
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1-Palmitoyl-d9-2-Palmitoyl-sn-glycero-3-PE
Item number: Cay28155-500
1-Palmitoyl-d9-2-palmitoyl-sn-glycero-3-PE is intended for use as an internal standard for the quantification of 1,2-dipalmitoyl-sn-glycero-3-PE (Cay-15092) by GC- or LC-MS. 1,2-Dipalmitoyl-sn-glycero-3-PE (1,2-DPPE) is a naturally occurring PE containing C16:0 fatty acids at the sn-1 and sn-2 positions. It belongs...
| Keywords: | 16:0-d9/16:0-PE, 1-Hexadecanoyl-d9-2-Hexadecanoyl-sn-glycero-3-Phosphatidylethanolamine,... |
| Application: | GC-MS, LC-MS, internal standard, quantification |
| CAS | 2747990-85-6 |
| MW: | 701 D |
148.00€
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CCP-biotin Peptide (non-cyclized)
Item number: Cay35876-1
CCP-biotin peptide (non-cyclized) is a biotinylated and non-cyclized version of circular citrullinated peptide (CCP). The sequence corresponds to amino acids 447-467 of human filaggrin but contains Q447H, S449C, G459R, E460G, and S462C substitutions and is citrullinated at arginine 455. Cayman's CCP-biotin Peptide...
| Keywords: | Citrullinated Filaggrin (Q447H, S449C, G459R, E460G, S462C) (R455) (447-467)-biotin Peptide (non-cyclized), Cyclic... |
| Application: | Citrullinated/biotinylated filaggrin peptide derivative |
345.00€
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PAMAM Dendrimer G2.0 Succinamic Acid (water solution)
Item number: Cay39119-1
PAMAM dendrimer G2.0 succinamic acid (PAMAM G2.0 succinamic acid) is a polyamidoamine (PAMAM) dendrimer with succinamic acid termini. It has 16 surface groups. PAMAM G2.0 succinamic acid is an antagonist for the pore-forming channels anthrax toxin protective antigen 63 (PA63, IC50 = 879 nM) in lipid bilayers. It is...
| Keywords: | PAMAM G2.0 Succinamic Acid, Polyamidoamine Dendrimer G2.0 Succinamic Acid |
| Application: | Succinamic acid-terminated PAMAM dendrimer |
| MW: | 4856 D |
From 137.00€
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PAMAM Dendrimer G3.0 Succinamic Acid (water solution)
Item number: Cay39120-1
PAMAM dendrimer G3.0 succinamic acid (PAMAM G3.0 succinamic acid) is a polyamidoamine (PAMAM) dendrimer with succinamic acid termini that has been used as a drug delivery system in vivo. It is approximately 35 Å in diameter in PBS and has 32 surface groups. PAMAM G3.0 succinamic acid (10 µM) inhibits plaque...
| Keywords: | PAMAM G3.0 Succinamic Acid, Polyamidoamine Dendrimer G3.0 Succinamic Acid |
| Application: | Succinamic acid-terminated PAMAM dendrimer |
| MW: | 10109 D |
From 198.00€
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