Products from Cayman Chemical
Cayman Chemical Company, headquartered in Ann Arbor, Michigan, was founded in 1980 by Kirk Maxey, M.D. The company's goal is to help make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative stress, endocrinology, and many more. Cayman Chemical specializes in assay kits for the detection of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.
More information at: www.caymanchem.com
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Anti-Tryptophan Hydroxylase (Phospho-Ser58)
Item number: Cay10009397-1
Tryptophan hydroxylase (TPH) catalyzes the 5-hydroxylation of tryptophan, which is the first step in the biosynthesis of indoleamines (serotonin and melatonin). In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the Raphe nuclei of the brain, and melatonin synthesis takes place...
| Keywords: | TPH |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | rabbit |
645.00€
*
Anti-Tryptophan Hydroxylase (Phospho-Ser260)
Item number: Cay10009398-1
TPH catalyzes the 5-hydroxylation of tryptophan, which is the first step in the biosynthesis of indoleamines (serotonin and melatonin). In mammals, serotonin biosynthesis occurs predominantly in neurons which originate in the Raphe nuclei of the brain, and melatonin synthesis takes place within the pineal gland. TPH...
| Keywords: | TPH |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | rat |
645.00€
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Anti-Glycine Receptor
Item number: Cay10009399-1
Glycine is an important inhibitory transmitter in the brain stem and spinal cord. Glycine receptors are members of the ligand-gated ion channel family (LGICs) that mediate rapid chemical neurotransmission. The binding of glycine to its receptor produces a large increase in chloride conductance, which causes membrane...
| Keywords: | Anti-Glyr, Anti-Glra1, Anti-Glycine receptor 48 kDa subunit, Anti-Glycine receptor subunit alpha-1, Anti-Glycine receptor... |
| Application: | WB, IHC (frozen) |
| Host: | Rabbit |
| Species reactivity: | human, murine, rat |
645.00€
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Anti-Gap-43 (Phospho-Ser41)
Item number: Cay10009400-1
Gap-43 is thought to have an important role in development and plasticity because it is expressed at high levels in neuronal growth cones during development and during axonal regeneration. There is also evidence from knockout animals that Gap-43 serves to amplify path finding signals from the growth cone. Gap-43 is...
| Keywords: | Anti-phospho-Gap43, Anti-phospho-Protein F1, Anti-phospho-Neuromodulin, Anti-phospho-Growth-associated protein 43,... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | bovine, dog, chicken, human, murine |
645.00€
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Anti-ATF2 (Phospho-Ser490,498)
Item number: Cay10009410-1
The activating transcription factor 2 (ATF2, also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and is a member of the ATF/CREB family of leucine zipper proteins. ATF2 has been implicated in the transcriptional regulation of a number of genes including cytokines, cell cycle control, and apoptosis....
| Keywords: | Activating Transcription Factor 2 |
| Application: | WB, IHC (frozen) |
| Host: | Rabbit |
| Species reactivity: | human |
645.00€
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Anti-Ribosomal S6 Kinase 2
Item number: Cay10009411-1
The p90 ribosomal S6 kinases (RSKs) 1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits. Recent work suggests that RSK2 exerts a tonic...
| Keywords: | RSK2 |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | rat |
645.00€
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Anti-Tyrosine Hydroxylase (Phospho-Ser31)
Item number: Cay10009413-1
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in the synthesis of the catecholamines dopamine and norepinephrine. TH antibodies can therefore be used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease, and drug abuse. TH...
| Keywords: | TH |
| Application: | WB, IF (frozen), IHC (frozen) |
| Host: | Rabbit |
| Species reactivity: | rat |
645.00€
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Anti-Raf-1 (Phospho-Ser301)
Item number: Cay10009504-1
The Ras pathway is a critical signal transduction cascade involved in regulating cellular proliferation, differentiation, survival, and oncogenic transformation. Members of the Raf serine/threonine kinase family are key intermediates in this cascade, functioning to relay signals from activated Ras to the downstream...
| Keywords: | Anti-phospho-Raf, Anti-phospho-cRaf, Anti-phospho-Raf1, Anti-phospho-Raf-1, EC=2.7.11.1, Anti-phospho-Proto-oncogene... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | rat |
645.00€
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Anti-Raf-1 (Phospho-Ser642)
Item number: Cay10009505-1
The Ras pathway is a critical signal transduction cascade involved in regulating cellular proliferation, differentiation, survival, and oncogenic transformation. Members of the Raf serine/threonine kinase family are key intermediates in this cascade, functioning to relay signals from activated Ras to the downstream...
| Keywords: | Anti-phospho-Raf, Anti-phospho-cRaf, Anti-phospho-Raf1, Anti-phospho-Raf-1, EC=2.7.11.1, Anti-phospho-Proto-oncogene... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | rat |
645.00€
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Anti-PSD95
Item number: Cay10009506-1
PSD95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other proteins in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the...
| Keywords: | Postsynaptic Density Protein of 95 |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | rat |
645.00€
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Anti-MEK1 (Phospho-Thr386)
Item number: Cay10009517-1
MAP kinase kinase 1 (MEK1) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation . This pathway also plays a key role in synaptic plasticity in the brain . Activated MEK1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP...
| Keywords: | MAP Kinase Kinase 1, MAPKK1, Mitogen-activated Protein Kinase Kinase 1 |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | rat |
645.00€
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Anti-MEK1 (Phospho-Thr292)
Item number: Cay10009518-1
MAP kinase kinase 1 (MAPKK1) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation . This pathway also plays a key role in synaptic plasticity in the brain . Activated MEK1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP...
| Keywords: | MAP Kinase Kinase 1, MAPKK1, Mitogen-activated Protein Kinase Kinase 1 |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human |
645.00€
*