Products from Cayman Chemical
Cayman Chemical Company, headquartered in Ann Arbor, Michigan, was founded in 1980 by Kirk Maxey, M.D. The company's goal is to help make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative stress, endocrinology, and many more. Cayman Chemical specializes in assay kits for the detection of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.
More information at: www.caymanchem.com
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Trichostatin A
Item number: Cay89730-1
Trichostatin A is a potent, reversible inhibitor of class I, II, and IV histone deacetylases (HDACs). In human Jurkat T cells, trichostatin A arrests cell cycle progression in G1 and inhibits the activity of HDAC1 with an IC50 value of 70 nM. Trichostatin A selectively inhibits the removal of acetyl groups from the...
| Keywords: | TSA, 7-[4-(dimethylamino)phenyl]-N-hydroxy-4,6R-dimethyl-7-oxo-2E,4E-heptadienamide |
| Application: | HDAC inhibitor |
| CAS | 58880-19-6 |
| MW: | 302.4 D |
From 91.00€
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Nocodazole
Item number: Cay13857-5
Nocodazole is an antimitotic agent. It increases tubulin GTP hydrolysis four-fold and induces tubulin depolymerization. Nocodazole (4 µg/ml) halts the cell cycle in the mitotic phase and synchronizes WI38 cells in the G2/M phase. It also decreases neuronal mitochondrial transport and density in a transgenic...
| Keywords: | NSC 238159, Oncodazole, R 17934, N-[6-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid, methyl ester |
| Application: | Microtubule function studies, cell cycle arrest |
| CAS | 31430-18-9 |
| MW: | 301.3 D |
From 57.00€
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Ellman's Reagent
Item number: Cay400050-100
A substrate for all AChE-based ELISA kits.Formulation: A lyophilized powder.
| Keywords: | DTNB, 5,5´-dithiobis-(2-nitrobenzoic acid |
| Application: | Kit component |
From 40.00€
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BiP-20
Item number: Cay45618-10
BiP-20 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA and single-guide RNA (sgRNA) in vivo. LNPs containing BiP-20 are targeted to the liver. BiP-20-containing LNPs encapsulating Cas9 mRNA and transthyretin (TTR) sgRNA decrease serum levels...
| Keywords: | bis(2-octyldodecyl) (2-(dimethylamino)ethyl)phosphoramidate |
| Application: | Ionizable cationic lipid, LNP formation |
| MW: | 729.21 D |
From 418.00€
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C12 NBD dihydro Ceramide (d18:0/12:0)
Item number: Cay10008097-1
Ceramidase catalyzes the hydrolysis of the N-acyl linkage between the fatty acid and sphingosine base in ceramide to produce sphingosine and a free fatty acid. Three isoforms of ceramidases (acid, neutral, and alkaline) have been characterized based on differences in their catalytic pH optimum. C12 NBD dihydro...
| Keywords: | NBD Cer(d18:0/12:0), NBD Ceramide (d18:0/12:0),... |
| Application: | Bioactive lipid assays |
| CAS | 474943-05-0 |
| MW: | 661.9 D |
From 289.00€
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Pinolenic Acid ethyl ester
Item number: Cay10008658-10
Pinolenic acid is a polyunsaturated fatty acid found in Korean pine (Pinus orientalis) and maritime pine (Pinus pinaster) seed oils. Both oils have been found to have lipid-lowering properties. A diet containing maritime pine seed oil (MPSO) lowered high-density lipoprotein and ApoA1 levels in transgenic mice...
| Keywords: | 5Z,9Z,12Z-octadecatrienoic acid, ethyl ester |
| Application: | Bioactive lipid assays |
| CAS | 493015-74-0 |
| MW: | 306.5 D |
123.00€
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3-Formylsalicylic Acid
Item number: Cay23368-100
3-Formylsalicylic acid is a non-competitive inhibitor of estrone sulfatase (IC50 = 150 nM, Ki = 120 nM), the enzyme that converts estrone sulfate to estrone. 3-Formylsalicylic acid has been used in the synthesis of Schiff bases.. 3-Formylsalicylic acid is a non-competitive inhibitor of estrone sulfatase (IC50 = 150...
| Keywords: | NSC 55753, 3-formyl-2-hydroxy-benzoic acid |
| Application: | Non-competitive steryl-sulfatase inhibitor |
| CAS | 610-04-8 |
| MW: | 166.1 D |
From 95.00€
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11-deoxy Cortisol
Item number: Cay20775-1
11-deoxy Cortisol is a precursor in the biosynthesis of cortisol (Cay-20739). It is converted into cortisol by the cytochrome P450 (CYP) isoform CYP11B1, also known as 11beta-hydroxylase. Urinary levels of 11-deoxy cortisol and the ratio of 11-deoxy cortisol to cortisol are elevated in patients with...
| Keywords: | Compound S, Cortexolone, Cortodoxone, NSC 18317, Reichstein's Substance S, 17,21-dihydroxy-pregn-4-ene-3,20-dione |
| Application: | Biosynthetic cortisol precursor |
| CAS | 152-58-9 |
| MW: | 346.5 D |
From 49.00€
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Globopentaosylceramide (porcine RBC)
Item number: Cay36242-500
Globopentaosylceramides are glycosphingolipids and cell surface markers. They are present during oogenesis and preimplantation embryonic development and on primitive endoderm, extraembryonic visceral endoderm, embryonic stem cells, and pluripotent multilineage-differentiating stress-enduring (Muse) cells....
| Keywords: | Gb5, Globoside Gb5, SSEA-3, Stage-specific Embryonic Antigen-3,... |
| Application: | Sphingolipid |
| CAS | 171108-15-9 |
| MW: | 1501.89 D |
791.00€
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Anti-M13 (Clone MM05)
Item number: Cay38076-100
M13 Bacteriophage is a filamentous F-pilus-specific bacteriophage (Ff phage), which is a long, thin virus that infects bacterial host cells. It is composed of circular single-stranded DNA (ssDNA) encapsulated by one major coat protein, p8, and four minor coat proteins, p3, p6, p7, and p9, and has approximately 98.5%...
| Keywords: | Anti-M13 Phage |
| Application: | ELISA |
| Host: | Mouse |
From 123.00€
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Cardiolipin (16:0/18:1/16:0/18:1) (sodium salt)
Item number: Cay39282-10
Cardiolipin (16:0/18:1/16:0/18:1) is an anionic phospholipid containing the long-chain fatty acid palmitic acid (Cay-10006627) and the monounsaturated fatty acid oleic acid (Cay-90260, Cay-24659). It has been used in the synthesis of lipid nanodiscs for use in native mass spectrometry applications.. Cardiolipin...
| Keywords: | 16:0-18:1 Cardiolipin, 68:2-CL, CL(1'-[16:0/18:1],3'-[16:0/18:1]), Diphosphatidylglycerol (16:0/18:1), 9-octadecenoic acid... |
| Application: | Phospholipid |
| CAS | 2260669-35-8 |
| MW: | 1449.9 D |
From 189.00€
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Testosterone Hexahydrobenzoate
Item number: Cay41936-1
Testosterone hexahydrobenzoate (Cay-41936) is an analytical reference standard categorized as an anabolic androgenic steroid. Testosterone hexahydrobenzoate is a prodrug form of testosterone (Cay-ISO60154, Cay-ISO00154, Cay-15645). Testosterone hexahydrobenzoate is regulated as a Schedule III compound in the United...
| Keywords: | Testosterone Cyclohexanoate, (17beta)-17-[(cyclohexylcarbonyl)oxy]-androst-4-en-3-one |
| Application: | Analytical reference standard, anabolic androgenic steroid |
| CAS | 14191-92-5 |
| MW: | 398.58 D |
From 49.00€
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