Products from Cayman Chemical
Cayman Chemical Company, headquartered in Ann Arbor, Michigan, was founded in 1980 by Kirk Maxey, M.D. The company's goal is to help make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative stress, endocrinology, and many more. Cayman Chemical specializes in assay kits for the detection of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.
More information at: www.caymanchem.com
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Beauvericin
Item number: Cay11426-1
Beauvericin is a mycotoxin originally derived from B. bassiana, a common fungal parasite of arthropods. It is also produced by the fungus Fusarium, a pathogen of insects and plants. Beauvericin is cytotoxic against insect cells, killing the insect cell line SF-9 with a 50% cytotoxic concentration of 2.5 µM. In...
| Keywords: | cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)... |
| Application: | Mycotoxin, Apoptosis inducer |
| CAS | 26048-05-5 |
| MW: | 784 D |
From 55.00€
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MAHMA NONOate
Item number: Cay82130-10
MAHMA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 1 minute and 3 minutes at 37°C and 22-25°C, respectively, (pH 7.4) to liberate 2 moles of NO per mole of parent compound.Formal Name:...
| Keywords: | Methylamine hexamethylene methylamine NONOate, (Z)-1-[N-Methyl-N-[6-(N-methylammoniohexyl)amino]]diazen-1-ium-1,2-diolate |
| Application: | NO donor |
| CAS | 146724-86-9 |
| MW: | 204.3 D |
From 59.00€
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DEA NONOate
Item number: Cay82100-10
DEA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 2 minutes and 16 minutes at 37°C and 22-25°C, pH 7.4, respectively, to liberate 1.5 moles of NO per mole of parent compound.Formal Name: Diethylammonium (Z)-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate....
| Keywords: | DEA/NO, Diethylamine NONOate, Diethylammonium (Z)-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate |
| Application: | NO donor |
| CAS | 372965-00-9 |
| MW: | 206.3 D |
From 55.00€
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Dihomo-gamma-Linolenic Acid
Item number: Cay90230-10
Dihomo-gamma-Linolenic Acid (DGLA, 20:3), an elongation product of gamma-linolenic acid (18:3), is rapidly metabolized by fatty acid desaturases to produce arachidonic acid (20:4). DGLA is metabolized through the cyclooxygenase pathway to produce 1-series prostaglandins, including PGE1. In mice, DGLA supplementation...
| Keywords: | cis-8,11,14-Eicosatrienoic Acid, DGLA, gamma-Homolinolenic Acid, 8Z,11Z,14Z-eicosatrienoic acid |
| Application: | LTB4 receptor antagonist |
| CAS | 1783-84-2 |
| MW: | 306.5 D |
From 55.00€
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Gcn5 (human, recombinant)
Item number: Cay10782-100
Gcn5 and PCAF are highly homologous members of the Gcn5-related N-acetyltransferase (GNAT) superfamily of N-acetyltransferases involved in histone acetylation. Gcn5 and PCAF contain a highly conserved central core with divergent N- and C-terminal ends. Gcn5/PCAF are enzymatic subunits that exist in a mutually...
| Keywords: | hGCN5, hGCN5, STAF97, STAF97, Lysine acetyltransferase 2A, Lysine acetyltransferase 2A, Histone acetyltransferase GCN5,... |
| Application: | Enzyme activity |
| MW: | 96,3 kD |
661.00€
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Dihydroethidium
Item number: Cay12013-5
Dihydroethidium is a cell-permeable blue fluorescent dye that upon entering cells interacts with superoxide to form oxyethidium, which intercalates with nucleic acids and emits a red fluorescence detectable qualitatively by fluorescent microscopy or quantitatively by HPLC. It displays excitation/emission spectra of...
| Keywords: | Hydroethidine, PD-MY 003, 5-ethyl-5,6-dihydro-6-phenyl-3,8-phenanthridinediamine |
| Application: | Fluorescent dye, reactive oxygen detection |
| CAS | 104821-25-2 |
| MW: | 315.4 D |
From 74.00€
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Monensin (sodium salt)
Item number: Cay16488-1
Monensin is a naturally occuring ionophorous antibiotic that preferentially forms complexes with monovalent cations to enable transport across lipid membranes. Through its ability to affect pH and the sodium-potassium balance of a cell, monensin can induce cell death in Gram-positive bacteria such as Micrococcus,...
| Keywords: | Monensin A, NSC 343257,... |
| Application: | Ionophorous antibiotic |
| CAS | 22373-78-0 |
| MW: | 692.9 D |
From 51.00€
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Oligomycin A
Item number: Cay11342-5
Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin A, a dominant analog of the isomers, is an inhibitor of mitochondrial F1FO ATP synthase that induces apoptosis...
| Keywords: | MCH 32,... |
| Application: | Apoptosis inducer |
| CAS | 579-13-5 |
| MW: | 791.1 D |
From 87.00€
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Maresin 1
Item number: Cay10878-10
Maresin 1 is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids. It is produced from docosahexaenoic acid (DHA, Cay-90310, Cay-17950) in human peripheral blood mononuclear cells (PBMCs). Maresin 1 (100 nM) reduces TNF-alpha-induced increases in reactive oxygen species (ROS) in...
| Keywords: | 7(R)-MaR1, 7(R)-Maresin 1, 7R,14S-dihydroxy-4Z,8E,10E,12Z,16Z,19Z-docosahexaenoic acid |
| Application: | Inflammation studies |
| CAS | 1268720-28-0 |
| MW: | 360.5 D |
From 122.00€
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PSB-603
Item number: Cay25637-1
PSB-603 is an antagonist of the adenosine A2B receptor (Ki = 0.553 nM). It is selective for adenosine A2B over A1, A2A, and A3 receptors (Kis = >10,000 nM). It reduces intracellular calcium concentrations in Jurkat T cells expressing the human A2B receptor (IC50 = 1.13 nM). PSB-603 reduces Zika viral plaque...
| Keywords: | 8-[4-[[4-(4-chlorophenyl)-1-piperazinyl]sulfonyl]phenyl]-3,9-dihydro-1-propyl-1H-purine-2,6-dione |
| Application: | Adenosine receptor A2b antagonist |
| CAS | 1092351-10-4 |
| MW: | 529 D |
From 59.00€
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Progesterone ELISA Kit
Item number: Cay582601-96
Progesterone, along with pregnenolone, is the biosynthetic precursor of all other steroid hormones. Progesterone is synthesized from cholesterol by the sequential action of desmolase in the mitochondria, which produces pregnenolone, followed by Delta4,5-isomerase in the outer mitochondrial membrane and smooth...
| Keywords: | Progesterone EIA Kit |
| Application: | ELISA |
From 381.00€
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Palmitic Acid
Item number: Cay10006627-10
Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively. Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid...
| Keywords: | C16:0, hexadecanoic acid |
| Application: | Bioactive lipid assays |
| CAS | 57-10-3 |
| MW: | 256.4 D |
From 62.00€
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