Products from Cayman Chemical
Cayman Chemical Company, headquartered in Ann Arbor, Michigan, was founded in 1980 by Kirk Maxey, M.D. The company's goal is to help make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative stress, endocrinology, and many more. Cayman Chemical specializes in assay kits for the detection of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.
More information at: www.caymanchem.com
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SIN-1 (chloride)
Item number: Cay82220-10
As the active metabolite of molsidomine, SIN-1 (chloride) is a potent vasorelaxant and inhibitor of platelet aggregation. It produces both NO and superoxide and can therefore be used to generate peroxynitrite under physiological conditions.Formal Name: 5-amino-3-(4-morpholinyl)-1,2,3-oxadiazolium chloride. CAS...
| Keywords: | 3-Morpholino-sydnonimine, Linsidomine, 5-amino-3-(4-morpholinyl)-1,2,3-oxadiazolium chloride |
| Application: | Peroxynitrite generation |
| CAS | 16142-27-1 |
| MW: | 206.6 D |
From 51.00€
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(±)-Nutlin-3
Item number: Cay10004372-5
(±)-Nutlin-3 is a racemic mixture of the p53-Mdm2 protein-protein interaction inhibitor (-)-nutlin-3 (Cay-18585) and its less active enantiomer (+)-nutlin-3 (Cay-10009816). In vivo, (±)-nutlin-3 (200 mg/kg twice daily) reduces tumor volume in an SJSA-1 osteosarcoma mouse xenograft model.Formal Name:...
| Keywords: | rel-4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-pi... |
| Application: | Cell cycle arrest promotor |
| CAS | 548472-68-0 |
| MW: | 581.5 D |
From 59.00€
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Arachidonic Acid (peroxide free)
Item number: Cay90010.1-100
Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free arachidonic acid is a transient,...
| Keywords: | AA (peroxide free), 5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 506-32-1 |
| MW: | 304.5 D |
From 70.00€
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ADHP
Item number: Cay10010469-10
ADHP is a highly sensitive, stable substrate for horseradish peroxidase (HRP) that enables selective detection of H2O2. This colorless, non-fluorescent reagent reacts with H2O2 to produce the fluorescent compound resorufin, which can be analyzed using an excitation wavelength of 520-550 nm and an emission wavelength...
| Keywords: | A 6550, ADHP, Amplex Red(R), 1-(3,7-dihydroxy-10H-phenoxazin-10-yl)-ethanone |
| Application: | HRP substrate |
| CAS | 119171-73-2 |
| MW: | 257.2 D |
From 40.00€
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12(S)-HETE
Item number: Cay34570-25
12(S)-HETE is the predominant lipoxygenase product of mammalian platelets. It enhances tumor cell adhesion to endothelial cells, fibronectin, and the subendothelial matrix at 0.1 µM.Formal Name: 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid. CAS Number: 54397-83-0. Synonyms: 12(S)-Hydroxyeicosatetraenoic Acid....
| Keywords: | 12S-hydroxy-5Z,8Z,10E,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 54397-83-0 |
| MW: | 320.5 D |
From 229.00€
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L-Lactate Assay Kit
Item number: Cay700510-96
Cayman's L-Lactate Assay provides both a fluorescence and an absorbance-based method for detecting L-lactate in biological samples such as serum, plasma, blood, urine, and saliva. It can also be utilized to determine intracellular and extracellular lactate concentrations in cell culture samples. In the assay, LDH...
| Application: | Fluorescence-based L-lactate detection |
651.00€
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(1S,3R)-RSL3
Item number: Cay19288-5
(1S,3R)-RSL3 is a ferroptosis inducer and is canonically known as an inhibitor of glutathione peroxidase 4 (GPX4). It inhibits GPX4 in a context-dependent manner: (1S,3R)-RSL3 inhibits GPX4 in the presence of cell cytosol or recombinant human 14-3-3epsilon, an adaptor protein, but does not inhibit recombinant human...
| Keywords: | (1S,3R)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylic acid,... |
| Application: | GPX4 inhibitor |
| CAS | 1219810-16-8 |
| MW: | 440.9 D |
From 55.00€
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Purmorphamine
Item number: Cay10009634-10
Small molecules that promote osteoblast differentiation might be useful as therapeutic agents for bone diseases such as osteoporosis. Purmorphamine is a 2,6,9-trisubstituted purine that promotes the differentiation of both human and mouse mesenchymal progenitor cells into osteoblasts. The EC50 value for...
| Keywords: | 9-cyclohexyl-N-[4-(morpholinyl)phenyl]-2-(1-naphthalenyloxy)-9H-purin-6-amine |
| Application: | Differentiation promotor |
| CAS | 483367-10-8 |
| MW: | 520.6 D |
From 55.00€
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Beauvericin
Item number: Cay11426-1
Beauvericin is a mycotoxin originally derived from B. bassiana, a common fungal parasite of arthropods. It is also produced by the fungus Fusarium, a pathogen of insects and plants. Beauvericin is cytotoxic against insect cells, killing the insect cell line SF-9 with a 50% cytotoxic concentration of 2.5 µM. In...
| Keywords: | cyclo[(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)-2-hydroxy-3-methylbutanoyl-N-methyl-L-phenylalanyl-(2R)... |
| Application: | Mycotoxin, Apoptosis inducer |
| CAS | 26048-05-5 |
| MW: | 784 D |
From 55.00€
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Dihydroethidium
Item number: Cay12013-5
Dihydroethidium is a cell-permeable blue fluorescent dye that upon entering cells interacts with superoxide to form oxyethidium, which intercalates with nucleic acids and emits a red fluorescence detectable qualitatively by fluorescent microscopy or quantitatively by HPLC. It displays excitation/emission spectra of...
| Keywords: | Hydroethidine, PD-MY 003, 5-ethyl-5,6-dihydro-6-phenyl-3,8-phenanthridinediamine |
| Application: | Fluorescent dye, reactive oxygen detection |
| CAS | 104821-25-2 |
| MW: | 315.4 D |
From 74.00€
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MAHMA NONOate
Item number: Cay82130-10
MAHMA NONOate is a NO donor. It spontaneously dissociates in a pH-dependent, first-order process with a half-life of 1 minute and 3 minutes at 37°C and 22-25°C, respectively, (pH 7.4) to liberate 2 moles of NO per mole of parent compound.Formal Name:...
| Keywords: | Methylamine hexamethylene methylamine NONOate, (Z)-1-[N-Methyl-N-[6-(N-methylammoniohexyl)amino]]diazen-1-ium-1,2-diolate |
| Application: | NO donor |
| CAS | 146724-86-9 |
| MW: | 204.3 D |
From 59.00€
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Cysteinyl Leukotriene ELISA Kit
Item number: Cay500390-96
Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid via the 5-lipoxygenase (5-LO) pathway in leukocytes. LTC4, LTD4, and LTE4 are collectively referred to as cysteinyl leukotrienes (CysLTs). LTC4 and LTD4 are potent mediators of asthma and hypersensitivity. They induce...
| Keywords: | CysLT EIA Kit |
| Application: | ELISA |
From 595.00€
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