Products from Cayman Chemical
Cayman Chemical Company, headquartered in Ann Arbor, Michigan, was founded in 1980 by Kirk Maxey, M.D. The company's goal is to help make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative stress, endocrinology, and many more. Cayman Chemical specializes in assay kits for the detection of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.
More information at: www.caymanchem.com
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2'3'-cGAMP ELISA Kit
Item number: Cay501700-96
Cayman's 2'3'-cGAMP ELISA Kit is a competitive assay that can be used for quantification of 2'3'-cGAMP in cell lysates, plasma, serum, and tissue samples. This assay has a range of 6.1 pg/ml - 100 ng/ml (9 pM - 148.3 nM), with a midpoint (50% B/B0) of approximately 900 pg/ml (1,335 pM), and a sensitivity (80% B/B0)...
| Keywords: | 2'3'-cGAMP EIA Kit, 2'3'-Cyclic GMP-AMP, Guanosine-Adenosine 2',3'-cyclic monophosphate |
| Application: | ELISA |
777.00€
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Prostaglandin F2alpha ELISA Kit
Item number: Cay516011-96
Prostaglandin F2alpha (PGF2alpha) is one of the five primary PGs derived enzymatically directly from the endoperoxide PGH2. It was initially discovered in seminal fluid, and to date the majority of the functional roles ascribed to it relate to fertility, pregnancy, and parturition. PGF2alpha is a potent luteolytic...
| Keywords: | PGF2alpha EIA Kit |
| Application: | ELISA |
From 590.00€
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Cyclic AMP ELISA Kit
Item number: Cay581001-96
Cayman's cAMP assay is a very sensitive competitive ELISA that permits cAMP measurements within the standard curve range of 0.078-10 pmol/ml, typically with a sensitivity (80% B/B0) of 0.1 pmol/ml once samples and standards have been acetylated prior to analysis. This assay has been validated with culture media,...
| Keywords: | Adenosine 3',5'-cyclic mononucleotide, Adenosine 3',5'-cyclic monophosphate, cAMP EIA Kit |
| Application: | ELISA |
From 519.00€
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DNA/RNA Oxidative Damage (High Sensitivity) ELISA Kit
Item number: Cay589320-96
DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer. Guanine is the base is most prone to oxidation, and the repair processes initiated to correct the damage release multiple oxidized guanine species into the urine, including 8-hydroxyguanosine (8-OHG),...
| Keywords: | 8-hydroxy-2'-Deoxyguanosine, 8-OH-2dG, 8-OH-DG, DNA/RNA Oxidative Damage (High Sensitivity) EIA Kit |
| Application: | ELISA |
From 956.00€
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Cisplatin
Item number: Cay13119-50
Cisplatin is a platinum-containing compound that acts as a DNA-crosslinking agent and interferes with replication and transcription, culminating in apoptosis. It forms intra- and interstrand crosslinks with DNA with intrastrand guanine-to-guanine or guanine-to-alanine links accounting for the majority of DNA...
| Keywords: | cis-Diamminedichloroplatinum, CDDP, Cisplatinum, NSC 119875, (SP-4-2)-diamminedichloro-platinum |
| Application: | Alkylating agent, apoptosis inducer |
| CAS | 15663-27-1 |
| MW: | 300.1 D |
From 73.00€
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COX-2 (human) Inhibitor Screening Assay Kit
Item number: Cay701080-96
The COX-2 (human) Inhibitor Screening Assay directly measures PGF2alpha by stannous chloride (SnCl2) reduction of COX-derived PGH2 produced in the COX reaction. The prostanoid product is quantified via ELISA using an antiserum specific to PGF2alpha. This assay includes recombinant human COX-2 and is an excellent...
| Keywords: | Cyclooxygenase 2 |
| Application: | Inhibitor screening |
762.00€
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nor-NOHA (acetate)
Item number: Cay10006861-10
L-Arginine serves as a common substrate for both nitric oxide synthase (NOS) and arginase in the cell. NOS catalyzes the oxidation of arginine to citrulline and NO with Nomega-hydroxy-L-arginine (NOHA) formed as an intermediate. Arginase, on the other hand, catalyzes the hydrolysis of arginine into urea and...
| Keywords: | Nomega-hydroxy-nor-Arginine, 2S-amino-4-[[(hydroxyamino)iminomethyl]amino]-butanoic acid, diacetate |
| Application: | Arginase inhibitor |
| CAS | 1140844-63-8 |
| MW: | 296.3 D |
From 35.00€
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1-NA-PP1
Item number: Cay10954-10
1-NA-PP1 is a reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. 1-NA-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over...
| Keywords: | 1-Naphthyl-PP1, PP1 Analog, 1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| CAS | 221243-82-9 |
| MW: | 317.4 D |
From 37.00€
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BAY 60-7550
Item number: Cay10011135-1
The second messengers cAMP and cGMP are important mediators of signal transduction and hence a wide range of cellular processes including vasodilation and synaptic plasticity. Type 2 cyclic nucleotide phosphodiesterases (PDE2) isoforms inactivate cAMP and cGMP by hydrolyzing the phosphodiester bond. BAY 60-7550 is a...
| Keywords: | 2-[(3,4-dimethoxyphenyl)methyl]-7-[(1R)-1-hydroxyethyl]-4-phenylbutyl]-5-methyl-imidazo[5,1-f][1,2,4]triazin-4(1H)-one |
| Application: | PDE2 inhibitor |
| CAS | 439083-90-6 |
| MW: | 476.6 D |
From 144.00€
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2-Arachidonoyl Glycerol
Item number: Cay62160-1
2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the cannabinoid (CB) receptors CB1 and CB2 (Kis = 25.3-472 and 145-1,400 nM, respectively). Unlike arachidonoyl ethanolamide (AEA, Cay-90050), 2-AG is present at relatively high levels in the central nervous system and is the most abundant molecular species...
| Keywords: | 2-AG, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glyceryl ester |
| Application: | CB1 receptor agonist |
| CAS | 53847-30-6 |
| MW: | 378.6 D |
From 60.00€
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Nigericin (sodium salt)
Item number: Cay11437-5
Nigericin is a lipophilic potassium ionophore that has been found in S. hygroscopicus. It mediates neutral antiport of potassium and proton ions across mitochondrial membranes. Nigericin (10 µM) induces T. gondii egress in infected human foreskin fibroblasts (HFFs). It also induces NOD-like receptor protein 3...
| Keywords: | NSC 292567,... |
| Application: | Metabolic studies |
| CAS | 28643-80-3 |
| MW: | 747 D |
From 101.00€
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2-Hydroxypropyl-beta-cyclodextrin
Item number: Cay16169-25
2-Hydroxypropyl-beta-cyclodextrin (HP-beta-CD) is a cyclic oligosaccharide containing seven D-(+)-glucopyranose units that is widely used to improve the aqueous solubility of various compounds, especially those containing a phenyl group. The circular arrangement of its glucose units produces a torus-shaped ring...
| Keywords: | HP-beta-CD, 2-hydroxypropyl ethers beta-cyclodextrin |
| Application: | Solubility enhancer |
| CAS | 128446-35-5 |
| MW: | 1541.6 D |
From 60.00€
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