Products from Cayman Chemical
Cayman Chemical Company, headquartered in Ann Arbor, Michigan, was founded in 1980 by Kirk Maxey, M.D. The company's goal is to help make research possible by supplying scientists with biochemical tools in research disciplines such as cancer, nitric oxide, neuroscience, apoptosis, oxidative stress, endocrinology, and many more. Cayman Chemical specializes in assay kits for the detection of eicosanoids, free radical biomarkers, cyclic nucleotides, cytokines, hormones, and nitric oxide. In addition, Cayman Chemical offers a broad range of quality biochemicals including eicosanoids, nitric oxide reagents, and a variety of related lipids, fatty acids, enzymes, and antibodies.
More information at: www.caymanchem.com
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nor-NOHA (acetate)
Item number: Cay10006861-10
L-Arginine serves as a common substrate for both nitric oxide synthase (NOS) and arginase in the cell. NOS catalyzes the oxidation of arginine to citrulline and NO with Nomega-hydroxy-L-arginine (NOHA) formed as an intermediate. Arginase, on the other hand, catalyzes the hydrolysis of arginine into urea and...
| Keywords: | Nomega-hydroxy-nor-Arginine, 2S-amino-4-[[(hydroxyamino)iminomethyl]amino]-butanoic acid, diacetate |
| Application: | Arginase inhibitor |
| CAS | 1140844-63-8 |
| MW: | 296.3 D |
From 35.00€
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1-NA-PP1
Item number: Cay10954-10
1-NA-PP1 is a reversible, cell-permeable inhibitor of Src-family tyrosine kinases that have been mutated, by a single base substitution, to become 'analog sensitive' (as), as compared to the wild-type kinase. 1-NA-PP1 was first developed to optimally inhibit v-Src-as1, with an I338G substitution, preferentially over...
| Keywords: | 1-Naphthyl-PP1, PP1 Analog, 1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| CAS | 221243-82-9 |
| MW: | 317.4 D |
From 37.00€
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BAY 60-7550
Item number: Cay10011135-1
The second messengers cAMP and cGMP are important mediators of signal transduction and hence a wide range of cellular processes including vasodilation and synaptic plasticity. Type 2 cyclic nucleotide phosphodiesterases (PDE2) isoforms inactivate cAMP and cGMP by hydrolyzing the phosphodiester bond. BAY 60-7550 is a...
| Keywords: | 2-[(3,4-dimethoxyphenyl)methyl]-7-[(1R)-1-hydroxyethyl]-4-phenylbutyl]-5-methyl-imidazo[5,1-f][1,2,4]triazin-4(1H)-one |
| Application: | PDE2 inhibitor |
| CAS | 439083-90-6 |
| MW: | 476.6 D |
From 144.00€
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C11 BODIPY 581/591
Item number: Cay27086-1
C11 BODIPY 581/591 is a lipid-soluble ratiometric fluorescent indicator of lipid oxidation. Upon oxidation, its excitation maximum shifts from 581 to 500 nm and the emission maximum shifts from 591 to 510 nm. C11 BODIPY 581/591 has been used in the quantitation of ferroptosis.Formal Name:...
| Keywords: | (T-4)-difluoro[5-[[5-[(1E,3E)-4-phenyl-1,3-butadien-1-yl]-2H-pyrrol-2-ylidene-kappaN]methyl]-1H-pyrrole-2-undecanoato(2-)-... |
| Application: | Lipid-soluble ratiometric fluorescent lipid oxidation indicator |
| CAS | 217075-36-0 |
| MW: | 504.4 D |
230.00€
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2-Hydroxypropyl-beta-cyclodextrin
Item number: Cay16169-25
2-Hydroxypropyl-beta-cyclodextrin (HP-beta-CD) is a cyclic oligosaccharide containing seven D-(+)-glucopyranose units that is widely used to improve the aqueous solubility of various compounds, especially those containing a phenyl group. The circular arrangement of its glucose units produces a torus-shaped ring...
| Keywords: | HP-beta-CD, 2-hydroxypropyl ethers beta-cyclodextrin |
| Application: | Solubility enhancer |
| CAS | 128446-35-5 |
| MW: | 1541.6 D |
From 60.00€
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Resolvin E1
Item number: Cay10007848-10
Resolvin E1 (RvE1) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids. It is produced from eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908) via an 18-HEPE epoxide intermediate, which is formed by aspirin-acetylated COX-2-mediated oxidation of EPA and 5-lipoxygenase...
| Keywords: | RvE1, 5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 552830-51-0 |
| MW: | 350.5 D |
From 214.00€
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LY379268
Item number: Cay15351-10
LY379268 is a potent, brain-permeable, and selective agonist of group II metabotropic glutamate receptors (mGluRs), subtypes mGluR2 and mGluR3. In an assay of second messenger response, LY379268 exhibits EC50 values of 2.69 and 4.48 nM for human mGluR2 and mGluR3, respectively, with at least 80-fold selectivity over...
| Keywords: | (1R,4R,5S,6R)-4-amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylic acid |
| Application: | mGluR2 / mGluR3 agonist |
| CAS | 191471-52-0 |
| MW: | 187.2 D |
From 78.00€
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alpha-MSH (11-13) (trifluoroacetate salt)
Item number: Cay45458-1
alpha-MSH (11-13) is a peptide fragment of alpha-melanocyte-stimulating hormone (alpha-MSH, Item No. 29923), a neuropeptide with anti-inflammatory and immunomodulatory activity. It is bactericidal against methicillin-resistant S. aureus (MRSA) with ~10% survival when used at a concentration of 1 µM. alpha-MSH...
| Keywords: | KPV Peptide, Lys-Pro-Val-OH, Tripeptide KPV, alpha-Melanocyte-stimulating Hormone (11-13), L-lysyl-L-prolyl-L-valine,... |
| Application: | Alpha-MSH peptide fragment |
| MW: | 456.46 D |
From 35.00€
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Oxytocin ELISA Kit
Item number: Cay500440-480
Cayman's Oxytocin ELISA Kit is a competitive assay that can be used for quantification of oxytocin in plasma, urine, and saliva. The assay has a range from 5.9-750 pg/ml and a sensitivity (80% B/B0) of approximately 20 pg/ml.Synonyms: Otx, Oxytocin EIA Kit. Limit of Detection: 16 pg/ml. Assay Range: 5.9-750 pg/ml....
| Keywords: | Otx, Oxytocin EIA Kit |
| Application: | ELISA |
| Species reactivity: | human |
From 762.00€
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Thromboxane B2
Item number: Cay19030-1
Thromboxane B2 (TXB2) is a non-enzymatically derived, stable, inactive metabolite of TXA2, which is highly unstable. Serum levels of TXB2 positively correlate with platelet COX-1 activation. Urinary levels of TXB2 reflect intrarenal TXA2 synthesis, while its metabolites, 11-dehydro TXB2 (Cay-19500) and 2,3-dinor...
| Keywords: | TXB2, 9alpha,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 54397-85-2 |
| MW: | 370.5 D |
From 147.00€
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Leukotriene B4-d4
Item number: Cay320110-25
Leukotriene B4-d4 (LTB4-d4) is intended for use as an internal standard for the quantification of LTB4 (Cay-20110) by GC- or LC-MS. LTB4 is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion...
| Keywords: | LTB4-d4, 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic-6,7,14,15-d4 acid |
| Application: | Standard |
| CAS | 124629-74-9 |
| MW: | 340.5 D |
466.00€
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Myriocin
Item number: Cay63150-5
Myriocin is an amino fatty acid antibiotic derived from certain thermophylic fungi, in this case Mycelia sterilia. It is a potent immunosuppressant having 10- to 100-fold more activity than cyclosporin A. Myriocin is a potent inhibitor of serine palmitoyltransferase (Ki = 0.28 nM), the enzyme that catalyzes the...
| Keywords: | ISP-1, Thermozymocidin, 2S-amino-3R,4R-dihydroxy-2-(hydroxymethyl)-14-oxo-6E-eicosenoic acid |
| Application: | Serine palmitoyltransferase inhibitor |
| CAS | 35891-70-4 |
| MW: | 401.5 D |
From 55.00€
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