Products from BPS Bioscience
Sun, sea, and science: BPS Bioscience from San Diego, California promotes new scientific discoveries that lead to therapies by creating innovative solutions for research. BPS is an expert in recombinant proteins and enzymes, cell lines, virus-based tools, as well as biochemical and cellular assay systems. The high-quality products and services from BPS enable researchers worldwide to advance biological discoveries in a variety of disciplines, including epigenetics, cell signaling, SARS-CoV-2, immunotherapy, CRISPR, and adoptive cell therapies.
More information at: www.bpsbioscience.com
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PRAME TCR-T cells
Item number: BPS-82391
The PRAME TCR-T Cells are generated by high-titer lentiviral transduction of human primary CD4+ and CD8+ T cells with PRAME-Specific TCR Lentivirus (#78959). These ready-to-use TCR (T cell receptor)-T cells express the human TCR that specifically recognizes antigen PRAME (Preferentially Expressed Antigen in...
| Keywords: | Opa-interacting protein 4, OIP-4 1, publication Preferentially expressed antigen of melanoma, MAPE, |
| Application: | Positive control, PRAME TCR-T cell-driven cytotoxicity modulator screening |
2,710.00€
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TCR Knockout Electroporation Kit
Item number: BPS-82394
The TCR Knockout Electroporation Kit is suitable for Jurkat cell line and primary T cell engineering using electroporation. The kit contains both the Cas9 enzyme (Streptococcus pyogenes) and the gRNAs targeting TRAC (T-Cell Receptor Alpha Constant) and TRBC (targets both T Cell Receptor Beta Constant 1 and T Cell...
| Keywords: | CRISPR, TCR knockout, CAR-T, T cell receptor, |
| Application: | TCR alpha/beta knockout in cells of interest |
461.00€
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Untransduced T Cells (PRAME TCR-T Negative Control)
Item number: BPS-82397
The Untransduced T Cells (PRAME TCR-T Negative Control) were produced by mock lentiviral transduction of human primary CD4+ and CD8+ T cells. These cells are subjected to comparable manipulations as TCR (T cell receptor)-T cells: activation, spinoculation (without lentivirus), and antigen specific stimulation. These...
| Keywords: | PRAME, MAPE. OIP4, Opa-interacting protein 4, Preferentially expressed antigen of melanoma,, |
| Application: | Negative control (lentivirus-transduced PRAME TCR-T cells) |
1,417.00€
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PBMC Cytotoxicity Luciferase Assay Kit (RPMI 8226)
Item number: BPS-82725
The PBMC Cytotoxicity Luciferase Assay Kit (RPMI 8226) is a kit designed to determine the cytotoxicity profile of PBMCs (Peripheral Blood Mononuclear Cells) towards the Firefly Luciferase RPMI 8226 Cell Line. It uses the luminescence signal from Firefly Luciferase - RPMI 8226 Recombinant Cell Line to measure the...
| Keywords: | TNFRSF17, BCM, BCMA, Tumor necrosis factor receptor superfamily member 17, |
| Application: | Luciferase-based analysis, cytotoxicity assays |
4,305.00€
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STEAP1 HEK293 Cell Line
Item number: BPS-82749
STEAP1 HEK293 Cell Line is a HEK293 cell line expressing STEAP1 (six transmembrane epithelial antigen of the prostate 1, NM_012449.3) under the control of a cytomegalovirus (CMV) promoter. This cell line was generated by lentiviral transduction followed by puromycin selection and limited dilution. Individual clones...
| Keywords: | Six-transmembrane epithelial antigen of prostate 1, PRSS24, STEAP, |
| Application: | Therapeutic antibody/STEAP1 targeting ADC screening, STEAP1-directed CAR-T cell co-culture assays |
4,768.00€
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Firefly Luciferase A375 Cell line
Item number: BPS-82789
Firefly Luciferase A375 Cell Line is an A375 human melanoma cell line engineered to express Firefly luciferase driven by a CMV promoter. This cell line was generated by transduction with Firefly Luciferase Lentivirus (#79692-P).
| Keywords: | CDX Models, A375, |
| Application: | Internal co-culture killing assay control, in vitro/in vivo bioluminescence imaging |
1,781.00€
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MDM2-p53 Homogenous Assay Kit
Item number: BPS-82802
The MDM2-p53 Homogenous Assay Kit is designed to identify and assess the efficacy of inhibitors of MDM2 (mouse double minute 2 homolog) interaction with p53 by measuring their binding. The MDM2-p53 Homogeneous Assay Kit comes in a convenient 384-well AlphaLISA(R) format, with enough purified recombinant MDM2, p53,...
| Keywords: | E3 ubiquitin-protein ligase Mdm2, Double minute 2 protein (Hdm2), Oncoprotein Mdm2, RING-type E3 ubiquitin transferase... |
| Application: | Binding studies, screen small molecule inhibitor screening, drug discovery, HTS |
827.00€
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CD200R1:CD200 [Biotinylated] Inhibitor Screening...
Item number: BPS-82806
The CD200R1:CD200 [Biotinylated] Inhibitor Screening Chemiluminescence Assay Kit is an ELISA designed to assess the efficacy of inhibitors of the binding between CD200R1 (CD200 receptor 1) and CD200 (cluster of differentiation 200) protein for screening and profiling applications. This kit comes with enough purified...
| Keywords: | CD200R1 ,CD200R, CRTR2, MOX2R, OX2R, Cell surface glycoprotein CD200 receptor 1, MOX1, MOX2, CD200, My033, OX-2 membrane... |
| Application: | Binding inhibitor screening/studies, drug discovery, HTS |
2,191.00€
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CD20, VLP
Item number: BPS-102671-1
Human CD20 protein, full length encompassing amino acids 1-297(end). This construct is tag-free and was produced using VLP (virus-like particle) technology.
| Keywords: | Bp35, CD20, MS4A1, B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Leukocyte surface antigen Leu-16,... |
| Application: | Animal immunization, ELISA, PK assay |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 34,3 kD |
From 582.00€
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Mepolizumab
Item number: BPS-82842-1
Mepolizumab (SB 240563) is a humanized monoclonal antibody that binds to and neutralizes interleukin-5 (IL-5), the major cytokine involved in eosinophil proliferation, activation, and survival. Mepolizumab can be used for the research of eosinophilic granulomatosis with polyangiitis (EGPA) and severe eosinophilic...
| Keywords: | IL5, TRF, IL-5, Interleukin-5, T-cell replacing factor, B-cell differentiation factor I, Eosinophil differentiation factor, |
| Application: | FA (neutr.) |
| Species reactivity: | human |
From 603.00€
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Benralizumab
Item number: BPS-82843-1
Benralizumab (MEDI-563) is an interleukin-5 receptor alpha (IL-5Ralpha)-directed cytolytic monoclonal antibody that induces direct, rapid and nearly complete depletion of eosinophils via enhanced antibody-dependent cell-mediated cytotoxicity. Benralizumab can be used for severe eosinophilic asthma.1
| Keywords: | IL5R, CD125, IL5RA, IL-5RA, CDw125, IL-5R-alpha, IL-5R subunit alpha, IL-5 receptor subunit alpha, Interleukin-5 receptor... |
| Application: | Eosinophil depletion |
| Species reactivity: | human |
From 2,079.00€
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Bimagrumab
Item number: BPS-82876-1
Bimagrumab (Anti-ACVR2B Reference Antibody) is a human monoclonal antibody that blocks activin type II receptor (ActRII), with KDs of 1.7 pM and 434 pM for human ActRIIB and ActRIIA, respectively. Bimagrumab can be used for the research of pathological muscle loss and weakness.
| Keywords: | ACVR2B, ACTR-IIB, EC=2.7.11.30, Activin receptor type-2B, Activin receptor type IIB, |
| Application: | FC, ELISA, pathological muscle loss and weakness studies |
| Species reactivity: | human |
| MW: | 150 kD |
From 1,038.00€
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