Products from BPS Bioscience
Sun, sea, and science: BPS Bioscience from San Diego, California promotes new scientific discoveries that lead to therapies by creating innovative solutions for research. BPS is an expert in recombinant proteins and enzymes, cell lines, virus-based tools, as well as biochemical and cellular assay systems. The high-quality products and services from BPS enable researchers worldwide to advance biological discoveries in a variety of disciplines, including epigenetics, cell signaling, SARS-CoV-2, immunotherapy, CRISPR, and adoptive cell therapies.
More information at: www.bpsbioscience.com
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CDK6/Cyclin D2, GST-Tag Recombinant
Item number: BPS-102151
Complex of recombinant human full length CDK6 (cyclin dependent kinase 6) and CyclinD2. Both constructs contain an N-terminal GST-tag. The complex was affinity purified.
| Keywords: | CDK6, CDKN6, EC=2.7.11.22, Cyclin-dependent kinase 6, Cell division protein kinase 6, Serine/threonine-protein kinase... |
| Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Expressed in: | insect cells |
| Origin: | human |
| MW: | 66/60 kD |
731.00€
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CDK10/Cyclin M, GST-Tag Recombinant
Item number: BPS-102152
Complex of recombinant human full length CDK10 (cyclin dependent kinase 10) and CyclinM. Both constructs contain an N-terminal GST-tag. The complex was affinity purified.
| Keywords: | CDK10, EC=2.7.11.22, Cyclin-dependent kinase 10, Cell division protein kinase 10, Serine/threonine-protein kinase PISSLRE,... |
| Application: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Expressed in: | insect cells |
| Origin: | human |
| MW: | 67/52 kD |
774.00€
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HER2, Fc Fusion, Avi-Tag Recombinant
Item number: BPS-102196-1
Recombinant human HER2 (human epidermal growth factor receptor 2), encompassing amino acids 23-652 that correspond to the extracellular portion of the protein. This construct has a human IgG1 Fc domain at the C-terminus, followed by an Avi-Tag(TM). This protein was affinity purified.
| Keywords: | HER2, ERBB2, CD340, MLN 19, p185erbB2, EC=2.7.10.1, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Metastatic lymph node... |
| Application: | SDS-PAGE |
| Expressed in: | human cells |
| Origin: | human |
| MW: | 98+glyc. kD |
From 446.00€
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HER3, Fc Fusion, Avi-Tag, Biotin-Labeled Recombinant
Item number: BPS-102229-1
Recombinant human HER3 (human epidermal growth factor receptor 3), encompassing amino acids 20-643 corresponding to the extracellular domain. This construct contains an Fc domain of IgG1 fused to the C-terminus, followed by a C-terminal Avi-Tag(TM). This protein was affinity purified.
| Keywords: | HER3, ERBB3, EC=2.7.10.1, Proto-oncogene-like protein c-ErbB-3, Receptor tyrosine-protein kinase erbB-3, Tyrosine... |
| Application: | SDS-PAGE, avidin-pull down assays |
| Expressed in: | human cells |
| Origin: | human |
| MW: | 98+glyc. kD |
From 566.00€
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PRAME-Specific TCR Lentivirus
Item number: BPS-78959-1
PRAME-Specific TCR Lentivirus are replication incompetent, HIV-based, VSV-G-pseudotyped lentiviral particles ready to transduce nearly all types of mammalian cells, including primary and non-dividing cells. These viruses transduce cells with a TCR (T cell receptor) that specifically recognizes the human antigen...
| Keywords: | OIP-4, Opa-interacting protein 4, Preferentially expressed antigen of melanoma, Melanoma antigen preferentially expressed... |
| Application: | Positive control, experimental optimization, cell pool/stable cell line generation, puromycin select. |
| Species reactivity: | human |
From 1,795.00€
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PRAME TCR CD8+ NFAT-Luciferase Reporter Jurkat Cell Line
Item number: BPS-78997
PRAME TCR CD8+ NFAT-Luciferase Reporter Jurkat Cell Line was generated from T Cell Receptor (TCR) Knockout NFAT Luciferase Reporter Jurkat Cell Line (BPS Bioscience #78556) by overexpression of human CD8 (NM_001768.6) and a PRAME (Preferentially Expressed Antigen in Melanoma)-directed TCR using lentiviral...
| Keywords: | OIP-4, Opa-interacting protein 4, Preferentially expressed antigen of melanoma, Melanoma antigen preferentially expressed... |
| Application: | Co-culture bioassay design/optimiz., positive control, vaccine T cell immunogenicity in vitro system |
| Species reactivity: | human |
16,374.00€
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CL2A-SN38
Item number: BPS-82256-1
CL2A-SN38 is a SN38 derivative with a Mal-PEG attached peptide linker, it can easily react with antibody to form an antibody-drug conjugate (ADC). SN-38 is a potent DNA Topoisomerase I inhibitor. CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A linker is...
| Application: | ADC payload, potent DNA Topoisomerase I inhibitor |
| MW: | 1480,6 D |
From 2,253.00€
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Eribulin
Item number: BPS-82265-1
Eribulin is a microtubule targeting agent that is used for the research of metastatic breast cancer. Eribulin suppresses centromere dynamics at concentrations that arrest mitosis.
| Application: | ADC payload, microtubule targeting agent |
| MW: | 729,9 D |
From 1,997.00€
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Auristatin PE
Item number: BPS-82268-1
Auristatin PE is a novel synthetic Dolastatin 10 derivative. Auristatin PE inhibits tubulin polymerization, resulting in cell cycle arrest and induction of apoptosis.
| Keywords: | Soblidotin, |
| Application: | ADC payload, tubulin polymerization inhibitor, cell cycle arrest, apoptosis inducer |
| MW: | 702,0 D |
From 1,028.00€
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Dolastatin 10
Item number: BPS-82269-1
Dolastatin 10 is a potent antimitotic peptide that inhibits tubulin polymerization. Dolastatin 10 consists of four amino acids, in order from the amino terminus: dolavaline, valine, dolaisoleucine, and dolaproine.
| Application: | ADC payload, tubulin polymerization inhibitor, potent antimitotic peptide |
| MW: | 785,1 D |
From 1,448.00€
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MMAF
Item number: BPS-82270-1
Monomethyl auristatin F (MMAF) is an antitubulin agent that inhibits cell division by blocking the polymerization of tubulin. Because MMAF is highly toxic, it cannot be used as a drug itself. MMAF induces potent antitumor effects when conjugated via protease cleavable linkers to a monoclonal antibody targeting...
| Keywords: | Monomethyl auristatin F, |
| Application: | ADC payload, tubulin polymerization inhibitor, cell cycle arrest, toxin |
| MW: | 732,0 D |
From 1,154.00€
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MC-MMAF
Item number: BPS-82271-1
MC-MMAF is a precursor of antibody drug conjugate. Mal group is reactive with thiol bearing molecule. MMAF is a synthetic antineoplastic agent.
| Application: | ADC payload, synthetic antineoplastic agent |
| MW: | 925,2 D |
From 943.00€
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