Products from BPS Bioscience
Sun, sea, and science: BPS Bioscience from San Diego, California promotes new scientific discoveries that lead to therapies by creating innovative solutions for research. BPS is an expert in recombinant proteins and enzymes, cell lines, virus-based tools, as well as biochemical and cellular assay systems. The high-quality products and services from BPS enable researchers worldwide to advance biological discoveries in a variety of disciplines, including epigenetics, cell signaling, SARS-CoV-2, immunotherapy, CRISPR, and adoptive cell therapies.
More information at: www.bpsbioscience.com
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ADAR1 Activity TWO-Luciferase Reporter HEK293 Cell Line
Item number: BPS-82240
ADAR1 Activity TWO-Luciferase Reporter HEK293 Cell Line is a HEK293 cell line designed to monitor cell viability in parallel with ADAR1 (adenosine deaminase acting on RNA) enzyme activity. These cells were engineered to express ADAR1 (NM_001111.5) and an ADAR1 reporter construct. This construct is comprised of an...
| Keywords: | ADAR, p136, IFI-4, ADAR1, DRADA, K88DSRBP, Interferon-inducible protein 4, 136 kDa double-stranded RNA-binding protein,... |
| Application: | ADAR1 activity monitoring, inhibitor/activator studies, cell viability studies |
| Species reactivity: | human |
20,861.00€
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Chemi-Verse(TM) CDK1/CyclinA2 Kinase Assay Kit
Item number: BPS-82242
The Chemi-Verse(TM) CDK1/CyclinA2 Kinase Assay Kit is designed to measure CDK1 (cyclin dependent kinase 1)/CyclinA2 kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified recombinant CDK1/CyclinA2...
| Keywords: | CDC2, CDK1, p34 protein kinase, Cyclin-dependent kinase 1, Cell division protein kinase 1, Cell division control protein 2... |
| Application: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
1,307.00€
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Set8 Chemiluminescent Assay Kit
Item number: BPS-82244
The Set8 Chemiluminescent Assay Kit is an ELISA (enzyme-linked immunosorbent assay)-based assay designed to measure the histone methylase activity of Set8 (SET domain containing lysine methyltransferase 8) for screening and profiling applications. The Set8 assay kit comes in a convenient 96-well format, with enough...
| Keywords: | PRSET7, PR-Set7, PR/SET07, H4-K20-HMTase KMT5A, Lysine-specific methylase 5A, Lysine N-methyltransferase 5A, SET... |
| Application: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
1,064.00€
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Chemi-Verse(TM) CDK2/CyclinA2 Kinase Assay Kit
Item number: BPS-82247
The Chemi-Verse(TM) CDK2/CyclinA2 Kinase Assay Kit is designed to measure CDK2 (cyclin dependent kinase 2)/CyclinA2 kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified recombinant CDK2/CyclinA2...
| Keywords: | CDK2, CDKN2, p33 protein kinase, Cyclin-dependent kinase 2, Cell division protein kinase 2, |
| Application: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
842.00€
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Chemi-Verse(TM) CDK5/p35 Kinase Assay Kit
Item number: BPS-82249
The Chemi-Verse(TM) CDK5/p35 Kinase Assay Kit is designed to measure CDK5 (cyclin dependent kinase 5)/p35 kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent. The assay kit comes in a convenient 96-well format, with enough purified recombinant CDK5/p35 complex,...
| Keywords: | EC=2.7.11.1, TPKII catalytic subunit, Cyclin-dependent kinase 5, Cell division protein kinase 5, Cyclin-dependent-like... |
| Application: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Species reactivity: | human |
842.00€
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Molecular Glue/PROTAC(R) Optimization Kit for RBM39-DCAF15
Item number: BPS-82251
The Molecular Glue/PROTAC(R) Optimization Kit for RBM39-DCAF15 Binding is designed for the testing and profiling of Molecular Glues (MG)/PROTACs targeting the RBM39 (RNA-binding protein 39) and DCAF15 (DDB1 and CUL4 associated factor 15) interaction. The Molecular Glue/PROTAC(R) Optimization Kit for RBM39-DCAF15...
| Keywords: | CAPERalpha, CAPER alpha, Splicing factor HCC1, RNA-binding protein 39, RNA-binding motif protein 39, Hepatocellular... |
| Application: | RBM39 targeting Molecular Glue/PROTAC identification/optimization, DCAF15 targeting molecule design |
| Species reactivity: | human |
4,961.00€
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Exatecan Mesylate
Item number: BPS-82255-1
Exatecan Mesylate is a structural analog of camptothecin with increased water solubility, and it shows anticancer activity.
| Application: | Camptothecine derivative, antineoplastic, topoisomerase I inhibitor, ADC payload |
| MW: | 531,6 D |
From 442.00€
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SN-38
Item number: BPS-82257-1
SN-38 is an anti-tumor drug that is often linked to ADCs to be directly delivered to cells. It is also the active metabolite of the drug, irinotecan. Its mechanism of action is inhibition of DNA topoisomerase I, halting DNA synthesis and causing single-strand breaks in DNA.
| Keywords: | 7-Ethyl-10-hydroxycamptothecin, |
| Application: | Anti-tumor drug , active irinotecan metabolite, ADC payload |
| MW: | 392,4 D |
From 731.00€
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Doxorubicin HCl
Item number: BPS-82260-1
Doxorubicin Hydrochloride is the hydrochloride salt of doxorubicin, an anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin.
| Keywords: | Doxorubicin HCl salt, |
| Application: | Anthracycline antibiotic, antineoplastic, topoisomerase II inhibitor, ADC payload |
| MW: | 543,5 D |
From 496.00€
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N-(Iodoacetamido)-Doxorubicin
Item number: BPS-82261-1
N-(Iodoacetamido)-Doxorubicin is an iodine attached Doxorubicin. It can conjugate with molecules containing thiol, amine functional groups. Doxorubicin is an anthracycline antibiotic with antineoplastic activity.
| Application: | Topoisomerase II inhibitor derivate, ADC payload (thiol/amine functional groups) |
| MW: | 711,5 D |
From 1,739.00€
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7-O-(Amino-PEG4)-paclitaxel
Item number: BPS-82262-1
7-O-(Amino-PEG4)-paclitaxel contains a paclitaxel moiety which is used a treatment for certain types of cancers. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer makes the compound more compatible in aqueous media.
| Application: | ADC payload, antineoplastic, tubulin depolymerization inhibitor |
| MW: | 1101,2 D |
From 1,291.00€
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Paclitaxel
Item number: BPS-82263-1
Paclitaxel is used to treat various types of cancers. It works by inhibiting the division of cells.
| Application: | ADC payload, antineoplastic, tubulin depolymerization inhibitor |
| MW: | 853,9 D |
From 410.00€
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