Products from BPS Bioscience
Sun, sea, and science: BPS Bioscience from San Diego, California promotes new scientific discoveries that lead to therapies by creating innovative solutions for research. BPS is an expert in recombinant proteins and enzymes, cell lines, virus-based tools, as well as biochemical and cellular assay systems. The high-quality products and services from BPS enable researchers worldwide to advance biological discoveries in a variety of disciplines, including epigenetics, cell signaling, SARS-CoV-2, immunotherapy, CRISPR, and adoptive cell therapies.
More information at: www.bpsbioscience.com
No results were found for the filter!
Molecular Glue/PROTAC(R) Optimization Kit for RBM39-DCAF15
Item number: BPS-82251
The Molecular Glue/PROTAC(R) Optimization Kit for RBM39-DCAF15 Binding is designed for the testing and profiling of Molecular Glues (MG)/PROTACs targeting the RBM39 (RNA-binding protein 39) and DCAF15 (DDB1 and CUL4 associated factor 15) interaction. The Molecular Glue/PROTAC(R) Optimization Kit for RBM39-DCAF15...
| Keywords: | CAPERalpha, CAPER alpha, Splicing factor HCC1, RNA-binding protein 39, RNA-binding motif protein 39, Hepatocellular... |
| Application: | RBM39 targeting Molecular Glue/PROTAC identification/optimization, DCAF15 targeting molecule design |
| Species reactivity: | human |
4,961.00€
*
Exatecan Mesylate
Item number: BPS-82255-1
Exatecan Mesylate is a structural analog of camptothecin with increased water solubility, and it shows anticancer activity.
| Application: | Camptothecine derivative, antineoplastic, topoisomerase I inhibitor, ADC payload |
| MW: | 531,6 D |
From 442.00€
*
SN-38
Item number: BPS-82257-1
SN-38 is an anti-tumor drug that is often linked to ADCs to be directly delivered to cells. It is also the active metabolite of the drug, irinotecan. Its mechanism of action is inhibition of DNA topoisomerase I, halting DNA synthesis and causing single-strand breaks in DNA.
| Keywords: | 7-Ethyl-10-hydroxycamptothecin, |
| Application: | Anti-tumor drug , active irinotecan metabolite, ADC payload |
| MW: | 392,4 D |
From 731.00€
*
Doxorubicin HCl
Item number: BPS-82260-1
Doxorubicin Hydrochloride is the hydrochloride salt of doxorubicin, an anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin.
| Keywords: | Doxorubicin HCl salt, |
| Application: | Anthracycline antibiotic, antineoplastic, topoisomerase II inhibitor, ADC payload |
| MW: | 543,5 D |
From 496.00€
*
N-(Iodoacetamido)-Doxorubicin
Item number: BPS-82261-1
N-(Iodoacetamido)-Doxorubicin is an iodine attached Doxorubicin. It can conjugate with molecules containing thiol, amine functional groups. Doxorubicin is an anthracycline antibiotic with antineoplastic activity.
| Application: | Topoisomerase II inhibitor derivate, ADC payload (thiol/amine functional groups) |
| MW: | 711,5 D |
From 1,739.00€
*
7-O-(Amino-PEG4)-paclitaxel
Item number: BPS-82262-1
7-O-(Amino-PEG4)-paclitaxel contains a paclitaxel moiety which is used a treatment for certain types of cancers. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The hydrophilic PEG spacer makes the compound more compatible in aqueous media.
| Application: | ADC payload, antineoplastic, tubulin depolymerization inhibitor |
| MW: | 1101,2 D |
From 1,291.00€
*
Paclitaxel
Item number: BPS-82263-1
Paclitaxel is used to treat various types of cancers. It works by inhibiting the division of cells.
| Application: | ADC payload, antineoplastic, tubulin depolymerization inhibitor |
| MW: | 853,9 D |
From 410.00€
*
Cabazitaxel-500 mg
Item number: BPS-82264-1
Cabazitaxel is a chemotherapy drug used to treat certain types of cancers such as prostate cancer.
| Application: | ADC payload, antineoplastic, tubulin depolymerization inhibitor |
| MW: | 836,0 D |
From 763.00€
*
DM4
Item number: BPS-82266-1
Ravtansine (DM4) is a chemical derivative of maytansine which is used as a cytotoxic component of antibody-drug conjugates.
| Keywords: | Ravtansine, |
| Application: | ADC payload, antibody-drug conjugate cytotoxic component |
| MW: | 780,4 D |
From 710.00€
*
KRAS G12D TCR (Clone 10) CD8+ NFAT-Luciferase Reporter...
Item number: BPS-82303
KRAS G12D TCR (Clone 10) CD8+ NFAT-Luciferase Reporter Jurkat Cell Line was generated from T Cell Receptor (TCR) Knockout NFAT Luciferase Reporter Jurkat Cell Line (BPS Bioscience #78556) by overexpression of human CD8 (NM_001768.6) and KRAS (Kirsten sat sarcoma virus) G12D TCR (Clone 10) using lentiviral...
| Keywords: | KRAS, KRAS2, |
| Application: | Co-culture bioassay design/optimization, KRAS G12D TCR cell evaluation positive control |
| Species reactivity: | human |
17,040.00€
*
KRAS G12D TCR (Clone 9c) CD8+ NFAT-Luciferase Reporter...
Item number: BPS-82304
KRAS G12D TCR (Clone 10) CD8+ NFAT-Luciferase Reporter Jurkat Cell Line was generated from T Cell Receptor (TCR) Knockout NFAT Luciferase Reporter Jurkat Cell Line (BPS Bioscience #78556) by overexpression of human CD8 (NM_001768.6) and KRAS (Kirsten sat sarcoma virus) G12D TCR (Clone 10) using lentiviral...
| Keywords: | KRAS, KRAS2, |
| Application: | Co-culture bioassay design/optimization, KRAS G12D TCR cell evaluation positive control |
| Species reactivity: | human |
17,040.00€
*
PRAME Peptide (432-440)
Item number: BPS-82306
The PRAME Peptide (432-440, GLSNLTHVL) is a peptide corresponding to PRAME (Preferentially Expressed Antigen in Melanoma), amino acids 432-440. The PRAME peptide is widely used to stimulate human PRAME-specific CD8+ T cells.
| Keywords: | OIP-4, Opa-interacting protein 4, Preferentially expressed antigen of melanoma, Melanoma antigen preferentially expressed... |
| Application: | Human PRAME-specific CD8+ T cell stimulation |
| Origin: | human |
324.00€
*
