Products from Biotium
Biotium is a leading life science reagent manufacturer and supplier devoted to providing high-quality and innovative fluorescent tools that fuel scientific discovery. Biotium is uniquely poised to invent cutting-edge products through the synergy of chemistry and biology. The collaborative team applies chemistry-based principles toward producing solutions for life science and medical research. Since its founding in 2001, Biotium has developed over 30 patented technologies including GelRed® dyes, CF® Dyes, NucView® Caspase-3 Substrates, EvaGreen® Dyes, and TrueBlack® Background Reducers. In addition, as part of its commitment to environmental sustainability, Biotium provides Earth-friendly alternatives to researchers.
More information at: www.biotium.com
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Anti-Fibronectin(HFN7.1), CF488A conjugate, 0.1mg/mL
Item number: BOT-BNC880270-100
Fibronectin is a dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. It possesses at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Fibronectin is involved in cell adhesion, tissue organization, and wound healing....
| Keywords: | Fibronectin(HFN7.1), CF488A conjugate, 0.1mg/mL, |
| Application: | FA (publ.), IF (publ.), ELISA (publ.), IHC (paraffin) (verif.), WB (publ.) |
From 284.00€
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Anti-c-Myc(MYC275), CF488A conjugate, 0.1mg/mL
Item number: BOT-BNC880275-100
The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been...
| Keywords: | c-Myc(MYC275), CF488A conjugate, 0.1mg/mL, |
| Application: | IHC (paraffin) (verif.) |
From 284.00€
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Anti-TAG-72 / CA72.4(B72.3), CF488A conjugate, 0.1mg/mL
Item number: BOT-BNC880276-100
Recognizes an oncofetal antigen of 220 kDa, identified as a tumor-associated glycoprotein (TAG-72) with properties of a mucin. This MAb defines the mucin-carried sialylated-Tn epitope. TAG-72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80%...
| Keywords: | TAG-72 / CA72.4(B72.3), CF488A conjugate, 0.1mg/mL, |
| Application: | FC, surface (publ.), IHC (paraffin) (verif.), IP (publ.), RIA (publ.), WB (publ.) |
From 284.00€
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Anti-Glycophorin A / CD235a(GYPA/280), CF488A conjugate,...
Item number: BOT-BNC880280-100
Recognizes a sialoglycoprotein of 39 kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane...
| Keywords: | Glycophorin A / CD235a(GYPA/280), CF488A conjugate, 0.1mg/mL, |
| Application: | IHC (paraffin) (verif.), WB (verif.) |
From 284.00€
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Anti-Insulin(E2-E3), CF488A conjugate, 0.1mg/mL
Item number: BOT-BNC880281-100
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin...
| Keywords: | Insulin(E2-E3), CF488A conjugate, 0.1mg/mL, |
| Application: | IHC, frozen (publ.), IHC (paraffin) (verif.) |
From 284.00€
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Anti-CD66 (CEA)(COL-1), CF594 conjugate, 0.1mg/mL
Item number: BOT-BNC940002-100
This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and...
| Keywords: | CD66 (CEA)(COL-1), CF594 conjugate, 0.1mg/mL, |
| Application: | IHC (paraffin) (verif.), WB (verif.) |
From 284.00€
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Anti-CD45RO(UCHL-1), CF594 conjugate, 0.1mg/mL
Item number: BOT-BNC940003-100
Recognizes a 180-185 kDa protein, identified as isoform of leukocyte common antigen (CD45RO) (4th Leucocyte Typing Workshop: Code No. N31). The epitope recognized by this antibody is sensitive to neuraminidase digestion. This antibody reacts with mature activated T-cells, most thymocytes, and a sub-population of...
| Keywords: | CD45RO(UCHL-1), CF594 conjugate, 0.1mg/mL, |
| Application: | FA (publ.), FC, surface (verif.), IF (verif.), IHC (paraffin) (verif.), IP (publ.), WB (publ.) |
From 284.00€
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Anti-Bax(2D2), CF594 conjugate, 0.1mg/mL
Item number: BOT-BNC940004-100
This antibody recognizes a protein of 21 kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers...
| Keywords: | Bax(2D2), CF594 conjugate, 0.1mg/mL, |
| Application: | FC, intracellular (verif.), IF (verif.), IHC (paraffin) (verif.) |
From 284.00€
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Anti-bcl-2(8C8), CF594 conjugate, 0.1mg/mL
Item number: BOT-BNC940005-100
This antibody recognizes a protein of 25-26 kDa, identified as Bcl-2. This antibody shows no cross-reaction with Bcl-x or Bax proteins. Bcl-2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial...
| Keywords: | bcl-2(8C8), CF594 conjugate, 0.1mg/mL, |
| Application: | IHC (paraffin) (verif.), WB (verif.) |
From 284.00€
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Anti-bcl-x(BX006), CF594 conjugate, 0.1mg/mL
Item number: BOT-BNC940006-100
Bcl-x belongs to the Bcl-2 family of proteins and plays a crucial role in apoptosis. Bcl-X has two isoforms: Bcl-XL (long), a 26 kDa protein which suppresses cell death, and Bcl-XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2 and promotes...
| Keywords: | bcl-x(BX006), CF594 conjugate, 0.1mg/mL, |
| Application: | IHC (paraffin) (verif.), WB (verif.) |
From 284.00€
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Anti-Cyclin D1(DCS-6), CF594 conjugate, 0.1mg/mL
Item number: BOT-BNC940007-100
Recognizes a protein of 36 kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11, 14)(q13,...
| Keywords: | Cyclin D1(DCS-6), CF594 conjugate, 0.1mg/mL, |
| Application: | FC, intracellular (verif.), IHC (paraffin) (verif.), WB (verif.) |
From 284.00€
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Anti-MAGE A1(MA454), CF594 conjugate, 0.1mg/mL
Item number: BOT-BNC940008-100
Recognizes a protein of 42-46 kDa, identified as MAGE-1. This MAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8 T lymphocyte clones (CTL). The MAGE...
| Keywords: | MAGE A1(MA454), CF594 conjugate, 0.1mg/mL, |
| Application: | FC, intracellular (publ.), ELISA (publ.), IHC (paraffin) (verif.), WB (publ.) |
From 284.00€
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