Products from Biotium
Biotium is a leading life science reagent manufacturer and supplier devoted to providing high-quality and innovative fluorescent tools that fuel scientific discovery. Biotium is uniquely poised to invent cutting-edge products through the synergy of chemistry and biology. The collaborative team applies chemistry-based principles toward producing solutions for life science and medical research. Since its founding in 2001, Biotium has developed over 30 patented technologies including GelRed® dyes, CF® Dyes, NucView® Caspase-3 Substrates, EvaGreen® Dyes, and TrueBlack® Background Reducers. In addition, as part of its commitment to environmental sustainability, Biotium provides Earth-friendly alternatives to researchers.
More information at: www.biotium.com
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Anti-bcl-x(BX006), CF405S conjugate, 0.1mg/mL
Item number: BOT-BNC040006-100
Bcl-x belongs to the Bcl-2 family of proteins and plays a crucial role in apoptosis. Bcl-X has two isoforms: Bcl-XL (long), a 26 kDa protein which suppresses cell death, and Bcl-XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2 and promotes...
| Keywords: | bcl-x(BX006), CF405S conjugate, 0.1mg/mL, |
| Application: | IHC (paraffin) (verif.), WB (verif.) |
From 284.00€
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Anti-Cyclin D1(DCS-6), CF405S conjugate, 0.1mg/mL
Item number: BOT-BNC040007-100
Recognizes a protein of 36 kDa, identified as cyclin D1. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. This antibody neutralizes the activity of cyclin D1 in vivo. About 60% of mantle cell lymphomas (MCL) contain a t(11, 14)(q13,...
| Keywords: | Cyclin D1(DCS-6), CF405S conjugate, 0.1mg/mL, |
| Application: | FC, intracellular (verif.), IHC (paraffin) (verif.), WB (verif.) |
From 284.00€
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Anti-MAGE A1(MA454), CF405S conjugate, 0.1mg/mL
Item number: BOT-BNC040008-100
Recognizes a protein of 42-46 kDa, identified as MAGE-1. This MAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8 T lymphocyte clones (CTL). The MAGE...
| Keywords: | MAGE A1(MA454), CF405S conjugate, 0.1mg/mL, |
| Application: | FC, intracellular (publ.), ELISA (publ.), IHC (paraffin) (verif.), WB (publ.) |
From 284.00€
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Anti-MART-1 / Melan-A(M2-7C10), CF405S conjugate, 0.1mg/mL
Item number: BOT-BNC040009-100
This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous...
| Keywords: | MART-1 / Melan-A(M2-7C10), CF405S conjugate, 0.1mg/mL, |
| Application: | FC, intracellular (publ.), IF (publ.), IHC, frozen (publ.), IHC (paraffin) (verif.), WB (publ.) |
From 284.00€
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Anti-MART-1 / Melan-A(M2-9E3), CF405S conjugate, 0.1mg/mL
Item number: BOT-BNC040010-100
This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous...
| Keywords: | MART-1 / Melan-A(M2-9E3), CF405S conjugate, 0.1mg/mL, |
| Application: | IHC (paraffin) (verif.), WB (verif.) |
From 284.00€
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Anti-p63 (Squamous, Basal & Myoepithelial Cell...
Item number: BOT-BNC040011-100
p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it is not expressed in malignant tumors...
| Keywords: | p63 (Squamous, Basal & Myoepithelial Cell Marker)(TP63/11), CF405S conjugate, 0.1mg/mL, |
| Application: | IHC (paraffin) (verif.) |
From 284.00€
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Anti-Tyrosinase(T311), CF405S conjugate, 0.1mg/mL
Item number: BOT-BNC040012-100
Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the...
| Keywords: | Tyrosinase(T311), CF405S conjugate, 0.1mg/mL, |
| Application: | FC, intracellular (publ.), ELISA (publ.), IHC (paraffin) (verif.), IP (publ.), WB (publ.) |
From 284.00€
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Anti-p53(BP53-12), CF405S conjugate, 0.1mg/mL
Item number: BOT-BNC040013-100
This MAb reacts with an N-terminal epitope (aa 16-25) of both wild type and mutated p53. Mutation and/or allelic loss of p53 is one of the causes of a variety of mesenchymal and epithelial tumors. If it occurs in the germ line, such tumors run in families. In most transformed and tumor cells the concentration of p53...
| Keywords: | p53(BP53-12), CF405S conjugate, 0.1mg/mL, |
| Application: | IHC (paraffin) (verif.), WB (verif.) |
From 284.00€
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Anti-CD31 / PECAM-1(C31.7), CF405S conjugate, 0.1mg/mL
Item number: BOT-BNC040014-100
CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31...
| Keywords: | CD31 / PECAM-1(C31.7), CF405S conjugate, 0.1mg/mL, |
| Application: | FC, surface (verif.), IF (verif.), IHC (paraffin) (verif.), WB (verif.) |
From 284.00€
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Anti-CD56 / NCAM(123C3.D5), CF405S conjugate, 0.1mg/mL
Item number: BOT-BNC040015-100
This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135 kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the...
| Keywords: | CD56 / NCAM(123C3.D5), CF405S conjugate, 0.1mg/mL, |
| Application: | FC, surface (verif.), IF (verif.), IHC (paraffin) (verif.) |
From 284.00€
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Anti-Ep-CAM / CD326(VU-1D9), CF405S conjugate, 0.1mg/mL
Item number: BOT-BNC040017-100
This antibody reacts with the first EGF repeat in the extracellular domain of Ep-CAM. It is a 40-43 kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia...
| Keywords: | Ep-CAM / CD326(VU-1D9), CF405S conjugate, 0.1mg/mL, |
| Application: | Exosome staining (verif.), FC, surface (verif.), IF (verif.), IHC (paraffin) (verif.), WB (publ.) |
From 284.00€
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Anti-Kappa Light Chain(L1C1), CF405S conjugate, 0.1mg/mL
Item number: BOT-BNC040018-100
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However,...
| Keywords: | Kappa Light Chain(L1C1), CF405S conjugate, 0.1mg/mL, |
| Application: | IHC (paraffin) (verif.), WB (verif.) |
From 284.00€
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