Products from Biotium
Biotium is a leading life science reagent manufacturer and supplier devoted to providing high-quality and innovative fluorescent tools that fuel scientific discovery. Biotium is uniquely poised to invent cutting-edge products through the synergy of chemistry and biology. The collaborative team applies chemistry-based principles toward producing solutions for life science and medical research. Since its founding in 2001, Biotium has developed over 30 patented technologies including GelRed® dyes, CF® Dyes, NucView® Caspase-3 Substrates, EvaGreen® Dyes, and TrueBlack® Background Reducers. In addition, as part of its commitment to environmental sustainability, Biotium provides Earth-friendly alternatives to researchers.
More information at: www.biotium.com
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Anti-CD54 / ICAM-1(F4-31C2), 1mg/mL
Item number: BOT-BNUM1249-50
Recognizes an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1). It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types...
| Keywords: | CD54 / ICAM-1(F4-31C2), 1mg/mL, |
585.00€
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Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248),...
Item number: BOT-BNUM1256-50
Recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the...
| Keywords: | Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), 1mg/mL, |
| Application: | IHC (paraffin) (verif.) |
585.00€
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Anti-c-Myc Oncoprotein(MYC275 + MYC909), 1mg/mL
Item number: BOT-BNUM1269-50
This antibody recognizes a transcription factor of 64-67 kDa, identified as c-myc. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or over-expressed in a variety of tumors. Over-expression of c-myc protein occurs frequently...
| Keywords: | c-Myc Oncoprotein(MYC275 + MYC909), 1mg/mL, |
| Application: | IHC (paraffin) (verif.) |
585.00€
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Anti-Cytokeratin 10 (Suprabasal Epithelial Marker)...
Item number: BOT-BNUM1276-50
This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation, it is absent in the basal layer, appears in the first suprabasal layers and increases in...
| Keywords: | Cytokeratin 10 (Suprabasal Epithelial Marker) (KRT10/844 + KRT10/1275), 1mg/mL, |
| Application: | IHC (paraffin) (verif.) |
585.00€
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Anti-MUC1 / CA15-3 / EMA / CD227 (Epithelial...
Item number: BOT-BNC040431-100
MAb VU-4H5 reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of MAb VU4H5 is APDTR as established with 'epitope fingerprinting'. VU-4H5 preferentially binds to under-glycosylated 'tumor' MUC1. The extracellular domain of MUC1...
| Keywords: | MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker)(VU-4H5), CF405S conjugate, 0.1mg/mL, |
| Application: | IHC (paraffin) (verif.) |
From 284.00€
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Anti-MUC5AC (Mucin 5AC / Gastric Mucin)(1-13M1), CF405S...
Item number: BOT-BNC040432-100
This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma...
| Keywords: | MUC5AC (Mucin 5AC / Gastric Mucin)(1-13M1), CF405S conjugate, 0.1mg/mL, |
| Application: | IHC (paraffin) (publ.), RIA (publ.), WB (publ.) |
From 284.00€
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Anti-Beta-2-Microglobulin (B2M)(C21.48A1), CF405S...
Item number: BOT-BNC040433-100
Beta-2 microglobulin is a component of the class I major histocompatibility complex (MHC I) where it functions in antigen processing and presentation. Involved in the presentation of peptide antigens to the immune system. Human Beta-2 microglobulin is expressed on many types of cells including lymphocytes,...
| Keywords: | Beta-2-Microglobulin (B2M)(C21.48A1), CF405S conjugate, 0.1mg/mL, |
| Application: | FC, intracellular (verif.), IF (verif.), WB (verif.) |
From 284.00€
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Anti-MUC5AC (Mucin 5AC / Gastric Mucin)(2-12M1), CF405S...
Item number: BOT-BNC040438-100
This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC). Its epitope is located in the N-terminal cysteine rich part of the peptide core of MUC5AC, which is heavily glycosylated. Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. MAb 2-11M1 reacts...
| Keywords: | MUC5AC (Mucin 5AC / Gastric Mucin)(2-12M1), CF405S conjugate, 0.1mg/mL, |
| Application: | IHC (paraffin) (publ.), RIA (publ.), WB (publ.) |
From 284.00€
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Anti-EGFR(H9B4), CF405S conjugate, 0.1mg/mL
Item number: BOT-BNC040642-100
This MAb reacts with a cytoplasmic domain of EGFR. EGFR is a type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin & epiregulin. Primary...
| Keywords: | EGFR(H9B4), CF405S conjugate, 0.1mg/mL, |
| Application: | WB (verif.) |
From 284.00€
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Anti-Melanoma Marker (MART-1 + Tyrosinase + gp100)(DT101+...
Item number: BOT-BNC040704-100
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients....
| Keywords: | Melanoma Marker (MART-1 + Tyrosinase + gp100)(DT101+ BC199 + T311 + HMB45), CF405S conjugate, 0.1mg/mL, |
| Application: | IHC (paraffin) (verif.) |
From 284.00€
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Anti-CD20 / MS4A1 (B-Cell Marker)(L26), CF405S conjugate,...
Item number: BOT-BNC040766-100
This antibody recognizes a protein of 30-33 kDa, which is identified as CD20. Its epitope is located in the cytoplasmic domain of CD20 and was, therefore, ascribed as CD20cy in the 5th Workshop. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells,...
| Keywords: | CD20 / MS4A1 (B-Cell Marker)(L26), CF405S conjugate, 0.1mg/mL, |
| Application: | FC (verif.), IF (verif.), IHC (paraffin) (verif.), WB (verif.) |
From 284.00€
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Anti-CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell...
Item number: BOT-BNC040772-100
This antibody recognizes a single chain glycoprotein of 105/120 kDa, identified as CD30/Ki-1. Its epitope is located between aa112-412. CD30 is synthesized as a 90 kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120 kDa glycoprotein. In Hodgkin's disease,...
| Keywords: | CD30 / TNFRSF8 (Hodgkin & Reed-Sternberg Cell Marker)(Ber-H2), CF405S conjugate, 0.1mg/mL, |
From 284.00€
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