Products from Biotium
Biotium is a leading life science reagent manufacturer and supplier devoted to providing high-quality and innovative fluorescent tools that fuel scientific discovery. Biotium is uniquely poised to invent cutting-edge products through the synergy of chemistry and biology. The collaborative team applies chemistry-based principles toward producing solutions for life science and medical research. Since its founding in 2001, Biotium has developed over 30 patented technologies including GelRed® dyes, CF® Dyes, NucView® Caspase-3 Substrates, EvaGreen® Dyes, and TrueBlack® Background Reducers. In addition, as part of its commitment to environmental sustainability, Biotium provides Earth-friendly alternatives to researchers.
More information at: www.biotium.com
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Anti-CD11c (Dendritic Cell Marker)(ITGAX/1242), CF488A...
Item number: BOT-BNC881242-100
Recognizes a protein of 145 kDa, identified as CD11c. CD11c (ITGAX), a member of the leukointegrin family, shares the same beta subunit with other members of the leukocyte adhesion molecule family, which includes CD11a (LFA-1), CD11b (MAC-1) and CD11d (ITGAD), but has a unique alpha chain. CD11c has been shown to...
| Keywords: | CD11c (Dendritic Cell Marker)(ITGAX/1242), CF488A conjugate, 0.1mg/mL, |
| Application: | IHC (paraffin) (verif.) |
From 284.00€
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Anti-Spectrin beta III (SPTBN2) (SPTBN2/1247), CF488A...
Item number: BOT-BNC881247-100
Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II), four beta-subunits (beta-I-beta-IV) and a beta-H...
| Keywords: | Spectrin beta III (SPTBN2) (SPTBN2/1247), CF488A conjugate, 0.1mg/mL, |
From 284.00€
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Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248),...
Item number: BOT-BNC881256-100
Recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the...
| Keywords: | Prostate Specific Antigen (PSA)(KLK3/801 + KLK3/1248), CF488A conjugate, 0.1mg/mL, |
| Application: | IHC (paraffin) (verif.) |
From 284.00€
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Anti-Interferon alpha-2 (IFNA2)(N39), CF594 conjugate,...
Item number: BOT-BNC940298-100
This antibody recognizes a protein of 16-27 kDa, identified as human interferon-alpha-2 (IFN-a2). Its epitope maps between aa112-148 of IFN-a2 (total aa172). This MAb is specific for IFN-a2 and does not cross-react with interferon-alpha-1. The site recognized by this MAb is called site I and is responsible for the...
| Keywords: | Interferon alpha-2 (IFNA2)(N39), CF594 conjugate, 0.1mg/mL, |
From 284.00€
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Anti-MAP3K1 (Mitogen-Activated Protein Kinase Kinase...
Item number: BOT-BNC940316-100
Mitogen-activated protein (MAP) kinase cascades are activated by various extracellular stimuli, including growth factors. The MEK kinases (also designated MAP kinase kinase kinases, MKKKs, MAP3Ks or MEKKs) phosphorylate and thereby activate the MEKs (also called MAP kinase kinases or MKKs), including ERK, JNK and...
| Keywords: | MAP3K1 (Mitogen-Activated Protein Kinase Kinase Kinase 1)(2F6), CF594 conjugate, 0.1mg/mL, |
| Application: | IHC (paraffin) (verif.) |
From 284.00€
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Anti-CD13/Aminopeptidase-N(B-F10), CF594 conjugate, 0.1mg/mL
Item number: BOT-BNC940343-100
Recognizes an integral membrane glycoprotein of 150 kDa, identified as CD13 (also known as aminopeptidase-N). The CD13 antigen is present on most cells of myeloid origin including granulocytes, monocytes, mast cells, and GM-progenitor cells. It is also expressed by the majority of AML, CML in myeloid blast crisis,...
| Keywords: | CD13/Aminopeptidase-N(B-F10), CF594 conjugate, 0.1mg/mL, |
| Application: | FC, surface (publ.), WB (publ.) |
From 284.00€
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Anti-CDw78(DF1588), CF594 conjugate, 0.1mg/mL
Item number: BOT-BNC940353-100
This antibody reacts with a carbohydrate determinant, identified as CDw78 (Workshop V, Code CDw78.2). Epitope recognized by this MAb and Leu21 is the same. It is present on some immature and some peripheral blood B cells, and some B cell lines. Its expression is increased after B-cell activation in vitro. CDw78 is...
| Keywords: | CDw78(DF1588), CF594 conjugate, 0.1mg/mL, |
From 284.00€
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Anti-CD22(FR10B4), CF594 conjugate, 0.1mg/mL
Item number: BOT-BNC940358-100
Recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature...
| Keywords: | CD22(FR10B4), CF594 conjugate, 0.1mg/mL, |
| Application: | FC, surface (publ.) |
From 284.00€
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Anti-CD8a(Rabbit PAb), CF594 conjugate, 0.1mg/mL
Item number: BOT-BNC940386-100
CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). A majority of thymocytes and a subpopulation of mature T cells and NK cell express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase...
| Keywords: | CD8a(Rabbit PAb), CF594 conjugate, 0.1mg/mL, |
| Host: | Rabbit |
From 284.00€
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Anti-CD6 (Negative Marker of T-regulatory...
Item number: BOT-BNC940402-100
CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6...
| Keywords: | CD6 (Negative Marker of T-regulatory Cells)(SPV-L14), CF594 conjugate, 0.1mg/mL, |
| Application: | FC (verif.), FC, surface (publ.), FA (publ.), IF (publ.), IF (verif.) |
From 284.00€
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Anti-HLA-DRB (MHC II)(Bra30), CF594 conjugate, 0.1mg/mL
Item number: BOT-BNC940407-100
This MAb reacts with the HLA-DRB3 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells,...
| Keywords: | HLA-DRB (MHC II)(Bra30), CF594 conjugate, 0.1mg/mL, |
| Application: | FC, surface (publ.), FA (publ.), WB (publ.) |
From 284.00€
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Anti-HLA-DRB(L243), CF594 conjugate, 0.1mg/mL
Item number: BOT-BNC940458-100
This MAb reacts with the HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. It binds a conformational epitope on HLA-DR, which depends on the correct folding of the alpha/beta heterodimer. This MAb has been reported to block mixed lymphocyte reactions. The L243...
| Keywords: | HLA-DRB(L243), CF594 conjugate, 0.1mg/mL, |
| Application: | FC, surface (publ.), FA (publ.), IHC, frozen (publ.), ELISA (publ.), IP (publ.) |
From 284.00€
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