Products from Bethyl Laboratories
Bethyl Laboratories is based in Montgomery, Texas, USA. Bethyl's mission is to be the premier provider of polyclonal antibodies for the clinical and diagnostic research. Bethyl will do this by continuous identfication of new and emerging proteins of interest through collaborations with notable scientists and scholarly searches. The company is unique in their end-to-end control of the entire antibody lifecycle. From the veterinary facilities to the development, production and validation labs, the Bethyl team focuses on delivering quality products. This attention to quality at every step and the integration across each stage of the process means scientists can rely on Bethyl antibodies. Since 2021, Bethyl Laboratories is part of FORTIS Life Sciences.
More information at: www.fortislife.com/bethyl-laboratories
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Anti-GSK3-beta Recombinant Monoclonal
Item number: A700-223CF
Protein function: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC,...
| Keywords: | Anti-GSK3B, Anti-GSK-3 beta, EC=2.7.11.26, Anti-Glycogen synthase kinase-3 beta, Anti-Serine/threonine-protein kinase GSK3B |
| Application: | WB, IP |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
1,075.00€
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860.00€
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Anti-Cytokeratin 18 Monoclonal
Item number: A500-035ACF
Protein function: Involved in the uptake of thrombin-antithrombin complexes by hepatic cells. When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection. [The...
| Keywords: | Anti-K18, Anti-CYK18, Anti-CK-18, Anti-KRT18, Anti-PIG46, Anti-Keratin-18, Anti-Cytokeratin-18, Anti-Keratin, type I... |
| Application: | WB, IHC, ICC, FC |
| Host: | Mouse |
| Species reactivity: | human |
936.00€
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748.80€
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Anti-Cytokeratin 19 Monoclonal
Item number: A500-036ACF
Protein function: Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle. [The UniProt Consortium]
| Keywords: | Anti-K19, Anti-KRT19, Anti-CK-19, Anti-Keratin-19, Anti-Cytokeratin-19, Anti-Keratin, type I cytoskeletal 19 |
| Application: | WB, IHC, ICC |
| Host: | Mouse |
| Species reactivity: | human |
936.00€
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748.80€
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Anti-SOX2 Monoclonal
Item number: A500-037ACF
Protein function: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Binds to the proximal enhancer region of NANOG. Critical for early embryogenesis and for embryonic stem cell...
| Keywords: | Anti-SOX2, Anti-Transcription factor SOX-2 |
| Application: | WB, IHC, ICC |
| Host: | Mouse |
| Species reactivity: | human |
936.00€
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748.80€
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Anti-BRD7 Recombinant Monoclonal
Item number: A700-221CF
Protein function: Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at 'Tyr-216'. Down-regulates TRIM24-mediated...
| Keywords: | Anti-BRD7, Anti-BP75, Anti-Protein CELTIX-1, Anti-75 kDa bromodomain protein, Anti-Bromodomain-containing protein 7 |
| Application: | WB, IP, IHC, ICC, FC |
| Host: | Rabbit |
| Species reactivity: | human |
1,075.00€
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860.00€
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Anti-Neurofilament-L Recombinant Monoclonal
Item number: A700-224CF
Protein function: Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks. [The UniProt Consortium]
| Keywords: | Anti-NF68, Anti-NEFL, Anti-NF-L, Anti-68 kDa neurofilament protein, Anti-Neurofilament light polypeptide,... |
| Application: | WB, IP, IHC, ICC |
| Host: | Rabbit |
| Species reactivity: | human, rat |
1,075.00€
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860.00€
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Anti-TIF1 Alpha/TRIM24 Recombinant Monoclonal
Item number: A700-225CF
Protein function: Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and...
| Keywords: | Anti-RNF82, Anti-TRIM24, Anti-TIF1-alpha, EC=2.3.2.27, Anti-RING finger protein 82, Anti-E3 ubiquitin-protein ligase... |
| Application: | WB, IP |
| Host: | Rabbit |
| Species reactivity: | human |
1,075.00€
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860.00€
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Anti-PD-L1 Recombinant Monoclonal
Item number: A700-227CF
Protein function: Plays a critical role in induction and maintenance of immune tolerance to self (PubMed:11015443, PubMed:28813417, PubMed:28813410). As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443,...
| Keywords: | Anti-B7H1, Anti-PD-L1, Anti-CD274, Anti-B7-H1, Anti-hPD-L1, Anti-B7 homolog 1, Anti-PDCD1 ligand 1, Anti-Programmed death... |
| Application: | WB, IP, FC |
| Host: | Rabbit |
| Species reactivity: | human |
1,075.00€
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860.00€
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Anti-TCF1/TCF7 Recombinant Monoclonal
Item number: A700-228CF
Protein function: Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4(+) CD8(+) immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the...
| Keywords: | Anti-TCF7, Anti-TCF1, Anti-TCF-1, Anti-TCF-7, Anti-T-cell factor 1, Anti-Transcription factor 7, Anti-T-cell-specific... |
| Application: | WB, IHC, ICC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
1,075.00€
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860.00€
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Anti-CD79B Recombinant Monoclonal
Item number: A700-229CF
Protein function: Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by...
| Keywords: | Anti-B29, Anti-CD79B, Anti-CD79b, Anti-Ig-beta, Anti-B-cell-specific glycoprotein B29, Anti-Immunoglobulin-associated B29... |
| Application: | WB, IP, IHC, ICC, FC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
1,075.00€
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860.00€
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Anti-STAT3-pY705 Recombinant Monoclonal
Item number: A700-231CF
Protein function: Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth factors (PubMed:10688651, PubMed:12359225, PubMed:12873986, PubMed:15194700, PubMed:17344214, PubMed:18242580, PubMed:23084476). Once activated, recruits coactivators,...
| Keywords: | Anti-Acute-phase response factor, Anti-Signal transducer and activator of transcription 3 |
| Application: | WB, IP, IHC, ICC |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
1,075.00€
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860.00€
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Anti-CD79A Recombinant Monoclonal
Item number: A700-232CF
Protein function: Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B- cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface...
| Keywords: | Anti-IGA, Anti-CD79A, Anti-CD79a, Anti-Ig-alpha, Anti-MB-1 membrane glycoprotein, Anti-Surface IgM-associated protein,... |
| Application: | WB, IP, IHC, ICC |
| Host: | Rabbit |
| Species reactivity: | human |
1,075.00€
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860.00€
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