Products from BellBrook Labs

BellBrook Labs

BellBrook Labs is a leading provider of biochemical assay solutions for drug discovery and enzyme analysis. The company develops and markets innovative high-throughput screening (HTS) assays, validated enzymes and compatible reagents, and also supports customers with assay development, workflow validation and scientific services. With its proprietary Transcreener® and AptaFluor® platforms, BellBrook Labs enables sensitive, robust and user-friendly measurement methods for a wide range of enzymatic targets in pharmaceutical, biotech and academic research institutions.

More information at: www.bellbrooklabs.com

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Recombinant SIRT3 Enzyme, Active, Human
Recombinant SIRT3 Enzyme, Active, Human

Item number: BBL-2367

Active, human SIRT3 (AA 101-399) protein expressed and purified from E.Coli with an N-Terminal His tag. The enzyme has been thoroughly validated with the Transcreener OAADPr Assay Kit. For specific activity, please refer to the Certificate of Analysis for each individual enzyme lot. Purity is 95% in a composition of...
Keywords: SIRT3, SIR2-like protein 3, Regulatory protein SIR2 homolog 3, NAD-dependent protein delactylase sirtuin-3, NAD-dependent...
Application: HTS, drug discovery, enzyme assays
Expressed in: E.coli
Origin: human
From 454.00€ *
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Recombinant VPS4B, Active, Human
Recombinant VPS4B, Active, Human

Item number: BBL-2371

Active, human VPS4B (AA 1-444) full-length protein expressed and purified from E.Coli. The enzyme has been thoroughly validated with the Transcreener ADP Assay Kit. For specific activity, please refer to the Certificate of Analysis for each individual enzyme lot. Purity is 95% in a composition of 50 mM Tris-HCl, 500...
Keywords: VPS4B, Cell migration-inducing gene 1 protein, Suppressor of K(+) transport growth defect 1, Vacuolar protein...
Application: HTS, drug discovery, enzyme assays
Expressed in: E.coli
Origin: human
From 557.00€ *
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Recombinant APE2 Enzyme, Active, Human
Recombinant APE2 Enzyme, Active, Human

Item number: BBL-2381

Active, human APE2 enzyme, full-length, His-tagged protein expressed and purified from baculovirus-infected insect cells. The enzyme has been thoroughly validated with the Transcreener dAMP Assay Kit. For specific activity, please refer to the Certificate of Analysis for each individual enzyme lot. Purity is >70% in...
Keywords: APEX2, APEX nuclease 2, AP endonuclease XTH2, APEX nuclease-like 2, Apurinic-apyrimidinic endonuclease 2, DNA-(apurinic or...
Application: HTS, drug discovery, enzyme assays
Expressed in: Insect cells
Origin: human
From 671.00€ *
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Transcreener(R) GDP FP Assay
Transcreener(R) GDP FP Assay

Item number: BBL-3009-10K

The Transcreener(R) HTS Assay platform overcomes the need for time-consuming, one-off assay development for individual members within a group transfer enzyme family by utilizing a single set of assay reagents that detect an invariant product. The generic nature of the Transcreener HTS Assay platform eliminates...
Keywords: GTPase Activity Assay, GTPase Screening Assay
Application: HTS, drug discovery, enzyme assays
From 671.00€ *
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Transcreener(R) ADP2 TR-FRET Assay
Transcreener(R) ADP2 TR-FRET Assay

Item number: BBL-3011-10K

The Transcreener(R) ADP2 TR-FRET Red Assay is a competitive immunoassay for ADP with a far-red, time-resolved Förster-resonance-energy-transfer (TR-FRET) readout. Because it is highly selective for ADP, the assay can be used with any enzyme that converts ATP to ADP, regardless of what other substrates are used....
Keywords: Kinase Activity Assay, Kinase Inhibitor Screening Assay, ATPase Activity Assay, ATPase Inhibitor Screening Assay
Application: HTS, drug discovery, enzyme assays
From 945.00€ *
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Transcreener(R) UDP2 FP Assay
Transcreener(R) UDP2 FP Assay

Item number: BBL-3018-10K

The Transcreener(R) UDP2 FP Assay is a universal biochemical HTS assay for enzymes that produce UDP, including glycosyltransferase, galactosyltransferase, glucuronyltransferase, N-acetylglucosamyltransferase, N-acetlygalactosyltransferase, xylosyltransferase, and glycogen, cellulose, lactose and hyaluronan...
Keywords: Glycosyltransferase Activity Assay, Glycosyltransferase Inhibitor Screening Assay
Application: HTS, drug discovery, enzyme assays
From 865.00€ *
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Transcreener(R) AMP2/GMP2 TR-FRET Assay
Transcreener(R) AMP2/GMP2 TR-FRET Assay

Item number: BBL-3020-10K

The Transcreener(R) AMP2/GMP2 TR-FRET Red Assay is a competitive immunoassay for enzymes that produce AMP or GMP with a far-red, time-resolved Förster-resonance-energy-transfer (TR-FRET) readout. The assay relies on a highly specific monoclonal antibody that recognizes AMP or GMP with more than 1,000-fold...
Keywords: Phosphodiesterase Activity Assay, PDE Inhibitor Screening Assay
Application: HTS, drug discovery, enzyme assays
From 945.00€ *
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Transcreener(R) 2-5A OAS FP Activity Assay
Transcreener(R) 2-5A OAS FP Activity Assay

Item number: BBL-3027-10K

The Transcreener(R) OAS FP Assay is a far-red, competitive fluorescence polarization (FP) assay. The assay is designed to be used with the 2'-5'-oligoadenylate synthase (OAS) family of enzymes, such as OAS1, OAS2, and OAS3), that produce the product 2-5A. The Transcreener OAS FP Assay is a simple biochemical assay...
Keywords: OAS Activity Assay, OAS Inhibitor Screening Assay
Application: HTS, drug discovery, enzyme assays
From 1,134.00€ *
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Enzolution(R) TREX1 Assay System
Enzolution(R) TREX1 Assay System

Item number: BBL-3029-10K

The Enzolution(R) TREX1 Assay System is intended for use with the Transcreener(R) dAMP FP Assay Kit (Part #3028) to measure enzymatic activity for TREX1 (also known as Three Prime Repair Exonuclease 1). TREX1 is the major exonuclease responsible for degrading cytosolic DNA, and it plays an important role in...
Keywords: TREX1, Deoxyribonuclease III, 3'-5' exonuclease TREX1, Three-prime repair exonuclease 1
Application: HTS, drug discovery, enzyme assays
From 626.00€ *
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Enzolution(R) PARG Assay System
Enzolution(R) PARG Assay System

Item number: BBL-3033-10K

The Enzolution(R) PARG Assay System is intended for use with the Transcreener(R) ADPR FP Assay Kit (Part #3030) to measure enzymatic activity for PARG (poly(ADP-ribose) glycohydrolase). PARG produces ADPR from the breakdown of poly(ADP-ribose) (polyADPR). It plays an important role in DNA damage repair and has been...
Keywords: PARG, Poly(ADP-ribose) glycohydrolase
Application: HTS, drug discovery, enzyme assays
From 1,127.00€ *
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Enzolution(R) POLQ ATPase FP Assay System
Enzolution(R) POLQ ATPase FP Assay System

Item number: BBL-3034-10K-FP

The Enzolution(R) POLQ Helicase ATPase Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the DNA-dependent ATPase activity of the POLQ Helicase domain. POLQ (also known as DNA Polymerase Theta), is a multifunctional enzyme with template-dependent DNA polymerase, ATPdependent...
Keywords: POLQ, DNA polymerase eta, DNA polymerase theta
Application: HTS, drug discovery, enzyme assays
From 626.00€ *
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Enzolution(R) POLQ ATPase TR-FRET Assay System
Enzolution(R) POLQ ATPase TR-FRET Assay System

Item number: BBL-3034-10K-TR

The Enzolution(R) POLQ Helicase ATPase Assay System is intended for use with the Transcreener(R) ADP2 Assay Kits to measure the DNA-dependent ATPase activity of the POLQ Helicase domain. POLQ (also known as DNA Polymerase Theta), is a multifunctional enzyme with template-dependent DNA polymerase, ATPdependent...
Keywords: POLQ, DNA polymerase eta, DNA polymerase theta
Application: HTS, drug discovery, enzyme assays
From 626.00€ *
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