Products from AdipoGen Life Sciences
AdipoGen Life Sciences is a manufacturer of reagents for immunometabolism & advanced inflammation research. The headquarters are located in San Diego, USA with a manufacturing laboratory in Switzerland. A motivated team of highly skilled researchers develops new products for the Life Science Reagents Market in the areas cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cells and neurodegeneration. The major focus is on innovative and advanced ELISA-Kits. In addition to the antibody and protein facilities, AdipoGen also owns chemical laboratories, enabling the company to develop new and innovative biochemicals.
More information at: www.adipogen.com
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AMI-1
Item number: AG-CR1-0038-M005
Potent, cell permeable and specific protein arginine N-methyltransferase 1 (PRMT1) inhibitor (IC50 = 8, 8 µM), Does not compete for the AdoMet (S-adenosyl-L-methionine, SAM) binding site, Blocks peptide substrate binding, HIV-1 RT polymerase inhibitor (IC50 = 5, 0 µM).
| Keywords: | Arginine N-methyltransferase inhibitor-1 |
| Application: | PRMT1 inhibitor |
| MW: | 592,4 D |
From 39.00€
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RO-3306
Item number: AG-CR1-3515-M005
Selective CDK 1 inhibitor (Cdk1/B1 and Cdk1/A). Potential anti-cancer compound. Cell cycle arrest inducer at G1, S and G2/M. Apoptosis inducer in embryonic stem cells. Actively enhances downstream p53 signaling to promote apoptosis in AML cell lines. Suppresses phosphorylation of p53 at Ser315 and procaspase-8 at...
| Keywords: | (5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one |
| Application: | CDK1 inhibitor, Apoptosis inducer |
| CAS | 872573-93-8 |
| MW: | 351,5 D |
From 33.00€
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Colchicine
Item number: AG-CN2-0048-M500
Isolated from Colchicum autumnale. Anti-cancer compound - Microtubule assembly inhibitor - Depolymerizes microtubules and limits microtubule formation (inactivates spindle fibre formation) - Inhibits mitosis during cell division at metaphase by inhibiting spindle formation - Anti-inflammatory compound - Suppresses...
| Keywords: | NSC 757, EINECS 200-598-5 |
| Application: | Microtubule assembly inhibitor |
| CAS | 64-86-8 |
| MW: | 399,4 D |
From 77.00€
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Nocardamine
Item number: AG-CN2-0150-M001
Isolated from Streptomyces sp. K04-0144. Antibiotic. Anti-mycobacterial. Siderophore (iron (Fe) chelating compound). Inducer of morphological changes in insect cells. Antioxidant. Anticancer compound.
| Keywords: | Deferrioxamine E, Desferrioxamine E |
| Application: | Antibiotic, Siderophore |
| CAS | 26605-16-3 |
| MW: | 600,7 D |
From 149.00€
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Procyanidin A2
Item number: AG-CN2-0486-M001
Pale pink solid. Soluble in DMSO, 100% ethanol or methanol. Sparingly soluble in water (0.1 mg/ml). A-Type proanthocyanidine, Potent antioxidant. Free radical scavenger and lipid peroxidation inhibitor, Potent low-density lipoprotein (LDL) oxidation inhibitor, Antidiabetic. Prevents islet cell apoptosis,...
| Keywords: | (+)-Epicatechin-(4beta-8,2beta-O-7)-epicatechin, PCA2, Proanthocyanidin A2, PA2, Procyanidol A2, Procyanidin dimer A2 |
| Application: | GTFB inhibitor, Antioxidant |
| CAS | 41743-41-3 |
| MW: | 576,5 D |
From 61.00€
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Alsterpaullone
Item number: AG-CR1-0036-M001
Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor, Anti-tumor compound Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM), CDK5/p35 (IC50 = 40 nM), GSK-3beta (glycogen synthase kinase-3beta) inhibitor, Apoptosis inhibitor, Apoptosis inducer, Angiogenesis inhibitor.
| Keywords: | 9-Nitro-7,12-dihydroindolo-[3,2-d][1]benzazepin-6(5H)-one |
| Application: | CDK inhibitor |
| CAS | 237430-03-4 |
| MW: | 293,3 D |
From 66.00€
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SAG
Item number: AG-CR1-3506-M001
Cell permeable smoothened (Smo) agonist - Shown to induce Sonic hedgehog (Shh) pathway activation and counteracts cyclopamine inhibition of Smo - Acts as an activator of Smo at low concentrations and as an inhibitor of Smo at very high concentrations.
| Keywords: | N-Methyl-N'-(3-pyridinylbenzyl)-N'-(3-chlorobenzo[b]thiophene-2-carbonyl)-1,4-diaminocyclohexane |
| Application: | Smo Agonist |
| CAS | 912545-86-9 |
| MW: | 490,1 D |
From 55.00€
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Propionyl-L-carnitine . HCl
Item number: AG-CR1-3595-M025
White to off-white solid. Soluble in water, methanol, ethanol, DMSO or dimethyl formamide. Naturally occurring carnitine derivative formed by carnitine acetyltransferase during beta-oxidation of uneven chain fatty acids, with high affinity for muscular carnitine transferase. Increases cellular carnitine content,...
| Keywords: | PLC |
| Application: | Carnitine derivative |
| CAS | 119793-66-7 |
| MW: | 253,8 D |
From 66.00€
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Ibrutinib
Item number: AG-CR1-3620-M005
White solid. Soluble in DMSO. Slightly soluble in ethanol (1mg/ml). Insoluble in water. Potent and highly selective Bruton's tyrosine kinase (BTK) inhibitor. Orally bioavailable and irreversible inhibitor of BTK (IC50 = 0.5 nM) with antineoplastic activity, Binds to and irreversibly inhibits BTK activity, preventing...
| Keywords: | PCI-32765 |
| Application: | BTK inhibitor |
| CAS | 936563-96-1 |
| MW: | 440,5 D |
From 88.00€
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Bafilomycin B1
Item number: BVT-0004-M001
Macrolide antibiotic, Specific vacuolar-type H+ATPase inhibitor. Isolated from Streptomyces hygroscopicus.
| Keywords: | Setamycin, BRN4640118 |
| Application: | H+ATPase inhibitor |
| CAS | 88899-56-3 |
| MW: | 815,9 D |
From 55.00€
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Thaxtomin A
Item number: BVT-0206-M001
Phytotoxin, Plant cell necrosis inducer, Induces common scab disease of potato. Isolated from Streptomyces sp. Gö-Dra 17.
| Keywords: | Thaztomin A |
| Application: | Bioassays |
| CAS | 122380-18-1 |
| MW: | 438,4 D |
From 205.00€
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Chaetoglobosin C
Item number: BVT-0460-M001
White solid. Soluble in DMSO. Almost insoluble in water or usual organic solvents. Cytochalasan mycotoxin, derivative of chaetoglobosin A (BVT-0092). Phytotoxic and antifungal compound. Moderate cytotoxic compound.
| Keywords: | (21,22-Dihydro-19-ketone)-chaetoglobosin A |
| Application: | Mycotoxin |
| CAS | 50645-76-6 |
| MW: | 528,7 D |
245.00€
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