Products from AdipoGen Life Sciences
AdipoGen Life Sciences is a manufacturer of reagents for immunometabolism & advanced inflammation research. The headquarters are located in San Diego, USA with a manufacturing laboratory in Switzerland. A motivated team of highly skilled researchers develops new products for the Life Science Reagents Market in the areas cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cells and neurodegeneration. The major focus is on innovative and advanced ELISA-Kits. In addition to the antibody and protein facilities, AdipoGen also owns chemical laboratories, enabling the company to develop new and innovative biochemicals.
More information at: www.adipogen.com
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Luteolin
Item number: AG-CN2-0098-M005
Yellow solid. Soluble in DMSO, DMF, methanol or ethanol. Slightly soluble in water. Anticancer and antimetastatic, alpha-Glucosidase inhibitor, Topoisomerase I Inhibitor, Apoptosis inducer, Anti-inflammatory, 15-Lipoxygenase (15-LOX) inhibitor, IL-6 production inhibitor, Fatty acid synthase (FAS) inhibitor,...
| Keywords: | 3',4',5,7-Tetrahydroxyflavone, Luteolol, BRN 0292084, C.I. Natural Yellow 2, Digitoflavone, Flacitran, Flavopurpol,... |
| Application: | 15-LOX inhibitor |
| CAS | 491-70-3 |
| MW: | 286,2 D |
From 22.00€
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DAPT
Item number: AG-CR1-0016-M005
Cell permeable gamma-secretase inhibitor (IC50 = 115 nM for total beta-amyloid, IC50 = 200 nM for beta-amyloid 1-42), Reduces Abeta levels in vivo, Blocks the proteolytic processing of neurotrophin receptor alike death domain protein (NRADD), Does not inhibit persenilinase, Notch processing inhibitor, Enhances...
| Keywords: | N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-butyl ester |
| Application: | gamma-secretase inhibitor |
| CAS | 208255-80-5 |
| MW: | 432,5 D |
From 77.00€
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6BIO
Item number: AG-CR1-0056-M001
Phosphoinositide-dependent kinase 1 (PDK1) inhibitor, Potent, reversible and ATP-competitive glycogen synthase kinase-3alpha/beta (GSK-3alpha/beta) inhibitor, JAK/STAT3 signaling inhibitor, Apoptosis inducer, Potent antiproliferative agent in malignant lymphoid cell.
| Keywords: | 2Z,3E)-6-Bromoindirubin-3-oxime |
| Application: | PDPK1 inhibitor |
| CAS | 667463-62-9 |
| MW: | 356,2 D |
From 39.00€
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MnTBAP chloride
Item number: AG-CR1-0133-M050
Cell permeable superoxide dismutase (SOD) mimetic, Potent inhibitor of peroxynitrite-induced oxidative reactions (peroxynitrite scavenger), but not a scavenger of nitric oxide (NO), Neuronal apoptosis inhibitor, Protects T cells from superoxide generation, caspase-dependent DNA loss and cell death,...
| Keywords: | Manganese (III) tetrakis (4-benzoic acid)porphyrin chloride |
| Application: | SOD mimetic |
| MW: | 879,2 D |
From 28.00€
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Anti-Neutrophils (mouse), blocking, clone Nimp-R14...
Item number: AG-20B-0043PF-M002
Neutrophils are key components of the inflammatory response and as such contribute to the killing of microorganisms. In addition, recent evidence suggests their involvement in the development of the immune response. The Nimp-R14 mAb displays features of an optimal reagent allowing the selective depletion of mouse...
| Application: | FC, IHC, ICC, FA (Blocking) |
| Host: | Rat |
| Species reactivity: | mouse |
From 319.00€
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Jagged-1 (human):Fc (human, rec.)
Item number: AG-40A-0081-C050
Signal peptide and extracellular domain of human Jagged-1 (HJ1, CD339) (amino acids 1-1067) are fused at the C-terminus to the Fc portion of human IgG1. Inhibits adipogenesis of mesenchymal stem cells (MSCs). Induces Hes-1 in 3T3L-1 cells. Liquid. 0.2µm-filtered solution in PBS. Jagged-1 is a ligand for multiple...
| Keywords: | Protein Jagged-1, hJ1, CD339, JAG1 |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 150 kD |
From 242.00€
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Sterigmatocystin
Item number: BVT-0171-M001
Isolated from Aspergillus sp. (strain WDMH51). Soluble in DMSO, ethanol, methanol, pyridine or acetone. Intermediate of the biosynthetic pathway to aflatoxin B1. Mycotoxin. DNA synthesis inhibitor. Anticancer compound. Cytotoxic, carcinogenic and mutagenic. Acyl-CoA:cholesterol acyltransferase 2 (ACAT2) inhibitor....
| Keywords: | NSC 201423, NSC 204986 |
| Application: | DNA synthesis inhibitor |
| CAS | 10048-13-2 |
| MW: | 324,3 D |
From 60.00€
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Liraglutide
Item number: AG-CP3-0034-M001
Long-acting acylated glucagon-like peptide-1 (GLP-1) receptor agonist. Antidiabetic and antiobesity agent used clinically to treat type 2 diabetes mellitus. Binding to GLP-1R, activates AMP-activated protein kinase, consequently stimulates insulin secretion in pancreatic beta cells and suppresses glucagon secretion...
| Keywords: | Arg34Lys26-(N-?-(?-Glu(N-?-hexadecanoyl)))-GLP-1(7-37), NN2211, NNC 90-1170, Victoza |
| Application: | GLP-1 receptor agonist |
| CAS | 204656-20-2 |
| MW: | 3751.2 D |
From 55.00€
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Everolimus
Item number: AG-CN2-0520-M001
White to off-white solid. Soluble in DMSO (50mg/ml), ethanol (50mg/ml), methanol or DMF. Insoluble in water. Chemical. CAS: 159351-69-6. Formula: C53H83NO14. MW: 958.2. Isolated from Streptomyces hygroscopicus. Macrolide antibiotic, inhibiting bacterial protein synthesis. Orally available Rapamycin derivative that...
| Keywords: | 42-O-(2-Hydroxyethyl)rapamycin, NVP-RAD001, RAD001, SDZRAD, Zortress, Afinitor, Certican, Votubia |
| CAS | 159351-69-6 |
| MW: | 958,2 D |
From 36.00€
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Averufin
Item number: AG-CN2-0527-M001
Mycotoxin. Isolated from fungus Aspergillus versicolor. Biosynthetic precursor of aflatoxins. Antibiotic. Shows moderate antibacterial activity against Gram-positive bacteria. Oxidative phosphorylation (OXPHOS) inhibitor. Inhibits succinate cytochrome c reductase complex (III) of the respiratory chain in...
| Keywords: | (2S,6S)-7,9,11-Trihydroxy-2-methyl-3,4,5,6-tetrahydro-2H-2,6-epoxyanthra[2,3-b]oxocine-8,13-dione, BRN1299991 |
| Application: | Mycotoxin, Aflatoxin biosynthesis intermediate, Oxidative phosphorylation (OXPHOS) inhibitor |
| CAS | 14016-29-6 |
| MW: | 368.3 D |
154.00€
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Remdesivir
Item number: AG-CR1-3713-M025
Soluble in DMSO (50mg/ml). Remdesivir is an adenosine triphosphate analog with broad-spectrum antiviral activity. It is a prodrug that metabolizes into its active form GS-441524 (Prod. No. AG-CR1-3722). GS-441524 is an adenosine nucleotide analog in viral RNA production. It is a nucleotide analog inhibitor of...
| Keywords: | GS-5734 |
| Application: | Antiviral, Adenosine triphosphate analog |
| CAS | 1809249-37-3 |
| MW: | 602.6 D |
From 77.00€
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Anti-beta-Tubulin (beta-monoE), pAb (IN115)
Item number: AG-25B-0039-C050
Polyglutamylation is an evolutionarily conserved protein post-translational modification in which glutamate side chains of variable lengths are formed on the modified protein. The most prominent substrate is tubulin, the building block of microtubules (MTs). Polyglutamylation has been found on both, alpha- and...
| Keywords: | Anti-TUBB2, Anti-TUBB2A, Anti-Tubulin beta-2A chain, Anti-Tubulin beta class IIa |
| Application: | WB, ICC, IHC, IP |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
429.00€
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