Products from AdipoGen Life Sciences
AdipoGen Life Sciences is a manufacturer of reagents for immunometabolism & advanced inflammation research. The headquarters are located in San Diego, USA with a manufacturing laboratory in Switzerland. A motivated team of highly skilled researchers develops new products for the Life Science Reagents Market in the areas cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cells and neurodegeneration. The major focus is on innovative and advanced ELISA-Kits. In addition to the antibody and protein facilities, AdipoGen also owns chemical laboratories, enabling the company to develop new and innovative biochemicals.
More information at: www.adipogen.com
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COVID-19 Research
GS-441524 (Remdesivir Metabolite)
Item number: AG-CR1-3722-M050
Soluble in DMSO (10mg/ml) or DMF (10mg/ml). GS-441524 is the active metabolite of the broad-spectrum antiviral Remdesivir. GS-441524 is an adenosine nucleotide analog in viral RNA production. It is a nucleotide analog inhibitor of RNA-dependent RNA polymerases (RdRps). The compound interferes with the action of...
| Application: | Antiviral nucleoside analog, active remdesivir metabolite |
| CAS | 1191237-69-0 |
| MW: | 291.3 D |
From 55.00€
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Anti-Fibronectin (EDA), mAb (blocking) (IST-9)...
Item number: AG-20B-6001YPF-C100
Fibronectin is a major component of the extracellular matrix that binds to integrins, cell surfaces and various compounds including collagen, fibrin, heparin, DNA and actin. It occurs in two main forms: plasma and cellular fibronectin. EDA (Extra Domain A)-containing cellular fibronectin (EDA-FN) plays a major role...
| Keywords: | FN, Cold-insoluble Globulin, CIG, Fibronectin (EIIIA) |
| Application: | ELISA, FUNC (Blocking), ICC, IHC, WB |
| Host: | Mouse |
| Species reactivity: | chicken, bovine, dog, human, monkey, mouse, swine, rat |
From 308.00€
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Anti-TRAIL-R3 (human), clone TR3.06
Item number: AG-20B-0029-C100
Recognizes human TRAIL-R3. Does not cross-react with human TRAIL-R1, -R2 or -R4. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. TRAIL-R3 is a receptor for the cytotoxic ligand TRAIL. It lacks a cytoplasmic death domain and hence is not capable of inducing apoptosis. Protects cells against TRAIL...
| Keywords: | TRAIL Receptor 3, DcR1, TRID, TNFRSF10C, CD263 |
| Application: | FC, IHC, WB |
| Host: | Mouse |
| Species reactivity: | human |
396.00€
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Angiopoietin-2 (human) (rec.)
Item number: AG-40B-0114-3010
Human angiopoietin-2 (aa 19-496) is fused at the N-terminus to a FLAG-tag. Lyophilized. Contains PBS with trehalose and Brij35. Angiopoietin-1 (Ang-1) and Angiopoietin-2 (Ang-2) are closely related secreted ligands which bind with similar affinity to Tie-2. Tie-2 and angiopoietins have been shown to play critical...
| Keywords: | Ang-2, Ang2, Angpt2 |
| Application: | Bioassays |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 70 kD |
From 226.00€
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(+)-Brefeldin A
Item number: BVT-0190-M001
Protein transport from ER to Golgi inhibitor, ADP-ribosylation factor (Arf) inhibitor, Cytotoxic, Antibiotic, Antiviral, Apoptosis inducer, Antitumor compound, Intracellular collagen degradation inhibitor. Isolated from Eupenicillium brefeldianum.
| Keywords: | Ascotoxin, Decumbin |
| Application: | Protein transport from ER to Golgi inhibitor, ADP-ribosylation factor (Arf) inhibitor |
| CAS | 20350-15-6 |
| MW: | 280,4 D |
45.00€
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Jasplakinolide
Item number: AG-CN2-0037-C050
Isolated from Jaspis splendens. Cell permeable, non-fluorescent F-actin probe. Potent inducer of actin polymerization and stabilization. Competes with phallotoxins for actin binding. Antifungal and antiparasitic compound. Antiproliferative and anticancer compound. Apoptosis enhancer/inducer. Tool used for...
| Keywords: | Jaspamide, NSC 613009 |
| Application: | Actin polymerization inducer |
| CAS | 102396-24-7 |
| MW: | 709,7 D |
From 275.00€
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(R)-Roscovitine
Item number: AG-CR1-0006-M005
Potent and selective inhibitor of CDKs, More potent than olomoucine, Inhibits CDK1/cyclin B kinase (IC50 = 450 nM) , CDK2 (IC50 = 700 nM) and CDK5/p35 (IC50 = 160 nM), Inhibits M phase promoting factor (MPF) kinase activity, Arrests human fibroblasts in G1 phase, Antitumor compound, Activates the mitogen-activated...
| Keywords: | 6-Benzylamino-2-(R)-[(1-ethyl)-2-hydroxyethylamino]-9-isopropylpurine |
| Application: | CDK inhibitor |
| CAS | 186692-46-6 |
| MW: | 354,5 D |
From 33.00€
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Terrein
Item number: BVT-0193-M010
Antibacterial. Phytotoxin. Melanogenesis inhibitor by reducing tyrosinase production via extracellular signal-regulated protein kinase (ERK) activation. Keratinocyte and epidermis proliferation inhibitor. Anti-inflammatory modulator in pulpal inflammation. Angiogenesis inhibitor through angiogenin secretion...
| Keywords: | NSC 291308, 4,5-Dihydroxy-3-(1-propenyl)-2-cyclopenten-1-one |
| Application: | Antibacterial, Phytotoxin |
| CAS | 582-46-7 |
| MW: | 154,2 D |
From 125.00€
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Sclerotiorin
Item number: AG-CN2-0054-M001
Antibacterial, weak antagonist of human endothelin receptor A (ETA) and B (ETB), Cholesteryl ester transfer protein (CETP) activity inhibitor, Grb2-Shc binding inhibitor, potent aldose reductase inhibitor, potent reversible, non-competitive soybean lipoxygenase-1 (LOX-1) inhibitor, antioxidant. Free radical...
| Keywords: | (S-(R*,R*-(E,E)))-Sclerotiorin |
| Application: | Lox-1 inhibitor |
| CAS | 549-23-5 |
| MW: | 390,9 D |
From 99.00€
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Luteolin
Item number: AG-CN2-0098-M005
Yellow solid. Soluble in DMSO, DMF, methanol or ethanol. Slightly soluble in water. Anticancer and antimetastatic, alpha-Glucosidase inhibitor, Topoisomerase I Inhibitor, Apoptosis inducer, Anti-inflammatory, 15-Lipoxygenase (15-LOX) inhibitor, IL-6 production inhibitor, Fatty acid synthase (FAS) inhibitor,...
| Keywords: | 3',4',5,7-Tetrahydroxyflavone, Luteolol, BRN 0292084, C.I. Natural Yellow 2, Digitoflavone, Flacitran, Flavopurpol,... |
| Application: | 15-LOX inhibitor |
| CAS | 491-70-3 |
| MW: | 286,2 D |
From 22.00€
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DAPT
Item number: AG-CR1-0016-M005
Cell permeable gamma-secretase inhibitor (IC50 = 115 nM for total beta-amyloid, IC50 = 200 nM for beta-amyloid 1-42), Reduces Abeta levels in vivo, Blocks the proteolytic processing of neurotrophin receptor alike death domain protein (NRADD), Does not inhibit persenilinase, Notch processing inhibitor, Enhances...
| Keywords: | N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-butyl ester |
| Application: | gamma-secretase inhibitor |
| CAS | 208255-80-5 |
| MW: | 432,5 D |
From 77.00€
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6BIO
Item number: AG-CR1-0056-M001
Phosphoinositide-dependent kinase 1 (PDK1) inhibitor, Potent, reversible and ATP-competitive glycogen synthase kinase-3alpha/beta (GSK-3alpha/beta) inhibitor, JAK/STAT3 signaling inhibitor, Apoptosis inducer, Potent antiproliferative agent in malignant lymphoid cell.
| Keywords: | 2Z,3E)-6-Bromoindirubin-3-oxime |
| Application: | PDPK1 inhibitor |
| CAS | 667463-62-9 |
| MW: | 356,2 D |
From 39.00€
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