Products from AdipoGen Life Sciences
AdipoGen Life Sciences is a manufacturer of reagents for immunometabolism & advanced inflammation research. The headquarters are located in San Diego, USA with a manufacturing laboratory in Switzerland. A motivated team of highly skilled researchers develops new products for the Life Science Reagents Market in the areas cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cells and neurodegeneration. The major focus is on innovative and advanced ELISA-Kits. In addition to the antibody and protein facilities, AdipoGen also owns chemical laboratories, enabling the company to develop new and innovative biochemicals.
More information at: www.adipogen.com
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D-erythro-Dihydrosphingosine 1-phosphate
Item number: AG-CR1-0005-M001
Saturated analog of sphingosine 1-phosphate (1-SP1), Ligand for sphingosine 1-phophate (S1P/EDG) receptors, Negative control for intracellular effects of sphingosine 1-phosphate, Induces chemotaxis, Antifibrotic.
| Keywords: | (2S,3R)-Dihydro-sphingosine 1-phosphate, Dihydro-S1P, dhS1P |
| Application: | Bioassays |
| MW: | 381,5 D |
From 105.00€
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JC-10 (high purity)
Item number: AG-CR1-3600-M005
Deep blue to violet solid. Soluble in water or DMSO. JC-10 is superior analog of JC-1, useful for determining mitochondrial membrane potential (MMP) in cells by flow cytometry, fluorescence microscopy and in microplate-based fluorescent assays. JC-10 is a cationic, lipophilic dye that accumulates in mitochondria of...
| Keywords: | Enhanced JC-1 |
| Application: | Mitochondrial function assays |
| MW: | 600 D |
From 83.00€
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Progranulin (human) (rec.)
Item number: AG-40A-0068Y-C050
Signal peptide and human progranulin (aa 1-593) are fused at the C-terminus to a FLAG(R)-tag. Activates ERK phosphorylation in THP-1 and MCF10A cells and induces cell migration of THP-1 monocytic leukemia cells. Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such...
| Keywords: | GRN, Proepithelin, PEPI, PC Cell-derived Growth Factor |
| Application: | Cell culture |
| Expressed in: | Human cells |
| Origin: | human |
| MW: | 76 kD |
From 187.00€
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Astaxanthin
Item number: AG-CN2-0055-M025
Potent antioxidant carotenoid. Free radical scavenger. Reduces oxidative stress. Anticancer compound. Anti-inflammatory. Blocks NF-kappaB activatin. Anti-hypertensive. Cardiovascular protective. Improves neuronal stem cell potential. Neuroprotective. Inhibits tumor invasion. Apoptosis inducer. Increases insulin...
| Keywords: | all-trans-Astaxanthin, Ovoester, NSC635689, 3,3'-Dihydroxy-beta-carotene-4,4'-dione, CCRIS 7118, HSDB 7468 |
| Application: | Antioxidant |
| CAS | 472-61-7 |
| MW: | 596,8 D |
From 50.00€
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COVID-19 Research
Ebselen
Item number: AG-CR1-0031-M025
Glutathione peroxidase mimetic, Peroxynitrite scavenger, Anti-inflammatory Antioxidant, Protein kinase C (PKC), NADPH, lipoxygenase, COX, NOS, H+ATPase and NADPH oxidase inhibitor, Antifungal, Review.
| Keywords: | 2-Phenyl-1,2-benzisoselenazol-3-(2H)-one |
| Application: | Antioxidant, Glutathione peroxidase mimetic |
| CAS | 60940-34-3 |
| MW: | 274,2 D |
From 18.00€
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Necrostatin-1
Item number: AG-CR1-2900-M005
Synthetic. Competitive indoleamine 2,3-dioxygenase (IDO) inhibitor. Cell permeable, potent and selective necroptosis (a non-apoptotic form of programmed cell death) inhibitor. Showed neuroprotection in a murine model of ischemic brain injury in vivo. Selective and ATP-competitive receptor-interacting protein kinase...
| Keywords: | Nec-1, MTH-Trp, MTH-DL-Tryptophan, Methyl-thiohydantoin DL-tryptophan,... |
| Application: | IDO inhibitor |
| CAS | 4311-88-0 |
| MW: | 259,3 D |
From 44.00€
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DLL1 (human):Fc (human) (rec.)
Item number: AG-40A-0116Y-C010
Signal peptide and extracellular domain of human DLL1 (aa 1-545) are fused at the C-terminus to the Fc portion of human IgG1. Lyophilized. Contains PBS. DLL1 (Delta-like protein, Delta1) is essential for postnatal arteriogenesis and contributes to tumor progression. DLL1 is involved in differentiation and...
| Keywords: | DLL1, Delta1, H-Delta-1, Delta-like protein 1, Drosophila Delta homolog |
| Application: | Bioassay |
| Expressed in: | Hamster cells |
| Origin: | human |
| MW: | 100 kD |
From 253.00€
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Ionomycin . calcium salt
Item number: AG-CN2-0418-M001
White to off-white solid. Soluble in DMSO, ethanol or methanol. Antibiotic, Potent and highly selective Ca2+ ionophore. Commonly used to modify intracellular calcium levels to study calcium transport across biological membranes and to calibrate fluorescent Ca2+ indicators, Ionomycin also transports Pb2+ and some...
| Keywords: | Antibiotic SQ 23377, EM 94 |
| Application: | Antibiotic, Potent and highly selective Ca2+ ionophore |
| CAS | 56092-82-1 |
| MW: | 747,1 D |
From 72.00€
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Cucurbitacin B
Item number: AG-CN2-0472-M001
Off-white powder. Soluble in DMSO. Microtubule polymerization inhibitor. Disrupts F-actin and induces nucleophosmin/B23 translocation, Immunomodulator with antimicrobial, anti-inflammatory and antitumorigenic properties, Induces apoptosis, autophagy and cell cycle arrest at G2/M phase in a range of cancer cell...
| Keywords: | Cuc B, 1,2-Dihydro-alpha-elaterin, Amarine, NSC 49451, NSC 144154 |
| Application: | Microtubule polymerization inhibitor |
| CAS | 6199-67-3 |
| MW: | 558,7 D |
From 39.00€
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Pioglitazone
Item number: AG-CR1-0067-M005
Thiazolidinedione (TZD) reference compound, Selective PPARgamma agonist, Selectively activates PPARgamma-1, Anti-diabetic , decreasing insulin resistance in adipose tissue, Is about one tenth as potent as rosiglitazone, Lipid metabolism modulator, Estrogen synthesis inhibitor, NF-kappaB inhibitor, Neuroprotective.
| Keywords: | 5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl-2,4-thiazolidinedione |
| Application: | PPARgamma agonist |
| CAS | 111025-46-8 |
| MW: | 356,4 D |
From 22.00€
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Pseudouridimycin
Item number: AG-CN2-0316-M001
Isolated from Streptomyces sp. Off-white to yellow powder. Soluble in DMSO or water. Peptidyl nucleoside antibiotic. Selective nucleoside-analog inhibitor of bacterial RNA polymerase (RNAP). Inhibits RNAP through a distinctive binding site on RNAP (the NTP addition site) and mechanism (competition with UTP for...
| Keywords: | PUM |
| Application: | Antibiotic, Bacterial RNA polymerase inhibitor |
| CAS | 1566586-52-4 |
| MW: | 486.4 D |
From 171.00€
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Semaglutide . AcOH
Item number: AG-CP3-0032-M025
Solid lyophilized powder. Soluble in aqueous solution (5% AcOH) (1mg/ml). Chemical. CAS: 910463-68-2 (parent). Formula: C187H291N45O59 . C2H4O2. MW: 4113.6 . 60.0. Synthetic. Glucagon-like peptide-1 (GLP-1) receptor agonist. Antidiabetic agent against type 2 diabetes (T2D). Stimulates insulin and suppresses glucagon...
| Keywords: | NN 9535, NNC 0113-0217, Ozempic |
| Application: | GLP-1 receptor agonist |
| MW: | 4173.6 D |
From 61.00€
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