Products from AdipoGen Life Sciences
AdipoGen Life Sciences is a manufacturer of reagents for immunometabolism & advanced inflammation research. The headquarters are located in San Diego, USA with a manufacturing laboratory in Switzerland. A motivated team of highly skilled researchers develops new products for the Life Science Reagents Market in the areas cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cells and neurodegeneration. The major focus is on innovative and advanced ELISA-Kits. In addition to the antibody and protein facilities, AdipoGen also owns chemical laboratories, enabling the company to develop new and innovative biochemicals.
More information at: www.adipogen.com
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Menadione
Item number: AG-CR1-3631-G001
Off-white to yellow solid. Soluble in DMSO (20mg/ml), ethanol (10mg/ml) or dimethylformamide (30mg/ml). Insoluble in water. Synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2 (menaquinone) after alkylation in vivo. The 1,4-naphthoquinone (NQ)...
| Keywords: | Vitamin K3, NSC4170, 2-Methyl-1,4-naphthalenedione |
| Application: | Anticancer compound, Apoptosis inducer |
| CAS | 58-27-5 |
| MW: | 172,2 D |
From 22.00€
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Anti-BAFF (mouse), clone Sandy-2 (blocking) (preservative...
Item number: AG-20B-0063PF-C500
BAFF is a master regulator of peripheral B cell survival and, together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren's...
| Keywords: | Anti-Baff, Anti-Tnfsf13b |
| Application: | FA, IP |
| Host: | Mouse |
| Species reactivity: | mouse |
From 462.00€
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X-Gal
Item number: AG-CC1-0003-G001
Chromogenic substrate for beta-galactosidase, Used in gene cloning (together with IPTG (Prod. No. AG-CC1-0002) to indicate whether a cell expresses the beta-galactosidase enzyme, which is encoded by the lacZ gene, in a technique called blue/white screening, Distinguishes between recombinant and non-recombinant...
| Keywords: | 5-Bromo-4-chloro-3-indolyl beta-D-galactoside |
| Application: | beta-galactosidase substrate |
| CAS | 7240-90-6 |
| MW: | 408,6 D |
From 28.00€
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LAG-3 (human):Fc (human, rec.)
Item number: AG-40B-0031-C050
The sequence coding for the 4 extracellular Ig-like domains of human LAG-3 (D1-D4) is fused to the Fc portion of human IgG1. Liquid. In PBS. Inhibits binding of MAb to LAG-3 (human) to LAG-3. Induces maturation of human dendritic cells. Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in...
| Keywords: | Lymphocyte Activation Gene-3, FDC Protein, CD223 |
| Application: | Bioassays |
| Expressed in: | CHO cells |
| Origin: | human, monkey, mouse |
| MW: | 80 kD |
363.00€
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Heptelidic acid
Item number: AG-CN2-0118-M001
Antibiotic - Potent selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor. Binds to the essential Cys149 residue in the catalytic site of GADPH - Anticancer compound. Selectively kills high-glycolytic cancer cells through glucose-dependent active ATP deprivation - Antimalarial - Apoptosis inhibitor....
| Keywords: | Koningic acid, Avocettin, FO-4443, BRN 5091359 |
| Application: | Antibiotic |
| Host: | Trichoderma sp |
| CAS | 74310-84-2 |
| MW: | 280,3 D |
From 143.00€
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Aspterric acid
Item number: AG-CN2-0132-M001
Isolated from Penicillium sp. Antibiotic. Pollen growth and development inhibitor.
| Application: | Antibiotic |
| CAS | 67309-95-9 |
| MW: | 266,3 D |
198.00€
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Boromycin
Item number: AG-CN2-0166-M001
Off-white solid. Soluble in DMSO, ethanol or methanol. Boron containing macrolide antibiotic, Antibacterial, Antiprotozoal (Plasmodium, Babesia), Anti-HIV compound, Ca2+ homeostasis modulator, Potentiator of bleomycin-induced anti-tumor activity, Used as a chiral selector in capillary electrophoresis.
| Keywords: | Antibiotic A 28829, Ivomycin, NSC216128 |
| Application: | Antibiotic |
| CAS | 34524-20-4 |
| MW: | 879,9 D |
From 132.00€
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Rebeccamycin
Item number: BVT-0139-C250
Antibiotic, Weak topoisomerase I (Topo I) inhibitor, Structurally similar to staurosporine, Does not show any inhibitory activity against protein kinases, Shows significant antitumor properties in vitro (IC50 = 480 nM against mouse B16 melanoma cells and IC50 = 500 nM against P388 leukemia cells). Isolated from...
| Keywords: | NSC 359079, BRN 4732638 |
| Application: | Topoisomerase I (Topo I) inhibitor |
| CAS | 93908-02-2 |
| MW: | 570,4 D |
From 100.00€
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Meglumine
Item number: AG-CN2-0413-G005
White to off-white crystalline powder. Soluble in DMSO or water. Slightly soluble in ethanol. Used as an excipient (an inert substance) in pharmaceuticals that improves solubility, drug release rate and stabilization of anionic drug substances, Counter ion used to replace sodium. It is impermeable towards cell...
| Keywords: | N-Methyl-D-glucamine, NSC52907, NSC7391, 1-Deoxy-1-methylaminosorbitol |
| Application: | Excipient, Counter ion |
| CAS | 6284-40-8 |
| MW: | 195,2 D |
From 28.00€
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Etoposide
Item number: AG-CR1-3572-M025
Potent anti-cancer compound. Induces apoptosis in normal and tumor cell lines. DNA Topoisomerase II activity inhibitor. Increases Topo II-mediated DNA breakage primarily by inhibiting the ability of the enzyme to religate cleaved nucleic acid molecules. Does not lead to immediate block of DNS synthesis, induces a...
| Keywords: | VP-16-213, NSC 141540 |
| Application: | Apoptosis Inducer |
| Host: | Semisynthetic |
| CAS | 33419-42-0 |
| MW: | 588,6 D |
From 33.00€
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COVID-19 Research
Tofacitinib
Item number: AG-CR1-3625-M005
Off-white to pale yellow solid. Soluble in DMSO or ethanol. Potent cell permeable JAK3 inhibitor (IC50 = 1nM). Shows also JAK-1 inhibitory activity, Immunosuppressive and anti-inflammatory agent, Inhibits signaling through heterodimeric receptors associated with JAK3, JAK1, or both of them, with functional...
| Keywords: | CP-690550, Xeljanz, Tasocitinib |
| Application: | Cell-permeable JAK3 inhibitor |
| CAS | 477600-75-2 |
| MW: | 312,4 D |
From 77.00€
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Epoxomicin
Item number: AG-CN2-0422-C100
White to off-white solid. Soluble in DMSO. Insoluble in water. Antibiotic, Potent anticancer compound, Cell permeable, potent, selective and irreversible 20S proteasome inhibitor. Predominantly inhibits the chymotrypsin-like (CTRL) activity of the proteasome. Exhibits lower level inhibition of proteasome...
| Keywords: | Antibiotic BU 4061T |
| Application: | Antibiotic, anticancer compound, Cell-permeable irreversible 20S proteasome inhibitor |
| CAS | 134381-21-8 |
| MW: | 554,7 D |
From 83.00€
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