Products from AdipoGen Life Sciences
AdipoGen Life Sciences is a manufacturer of reagents for immunometabolism & advanced inflammation research. The headquarters are located in San Diego, USA with a manufacturing laboratory in Switzerland. A motivated team of highly skilled researchers develops new products for the Life Science Reagents Market in the areas cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cells and neurodegeneration. The major focus is on innovative and advanced ELISA-Kits. In addition to the antibody and protein facilities, AdipoGen also owns chemical laboratories, enabling the company to develop new and innovative biochemicals.
More information at: www.adipogen.com
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COVID-19 Research
Auranofin
Item number: AG-CR1-3611-M025
White to off-white solid. Soluble in DMSO or 100% ethanol. Insoluble in water. Anti-inflammatory and anti-arthritic agent. Represses the activation of the NLRP3/IL-1beta pathway, Inhibitor of 5-lipoxygenase in human neutrophils, IKB kinase (IKK) by modifying Cys-179 of the IKKbeta subunit 5, Potent thioredoxin...
| Keywords: | 1-Thio-beta-D-glucopyranosatotriethylphosphine gold-2,3,4,6-tetra- acetate, NSC 321521, SKF 39162 |
| Application: | Antiinflammatory agent |
| CAS | 34031-32-8 |
| MW: | 678,5 D |
From 66.00€
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H-D-Val-Leu-Lys-pNA . 2HCl
Item number: AG-CP3-0042-M025
D-Val-Leu-Lys-p-nitroanilide is a selective colorimetric substrate for plasmin used to determine the formation of plasmin from plasminogen in amidolytic activity assays and plasminogen activating assays. Plasmin is a plasma serine protease whose main role is to dissolve fibrin blood clots. After cleavage by plasmin...
| Application: | Photometric plasmin substrate |
| CAS | 62354-43-2 |
| MW: | 551.5 D |
From 66.00€
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Anti-Cardif (human), clone Adri-1
Item number: AG-20B-0004-C100
Recognizes human Cardif. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. RIG-I (retinoic acid-inducible gene I, Ddx58) and MDA5 (melanoma differentiation-associated gene 5, also known as Ifih1 or Helicard) are proteins that sense viral replication intermediates, such as double-stranded RNA and...
| Keywords: | CARD Adapter Inducing Interferon-beta, IPS-1, Interferon-beta Promoter Stimulator Protein 1, MAVS, Mitochondrial Antiviral... |
| Application: | ICC, IHC, IP, WB |
| Host: | Mouse |
| Species reactivity: | human |
407.00€
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Anti-NLRP3/NALP3 (mouse), clone Cryo-1
Item number: AG-20B-0006-C100
Recognizes mouse NLRP3/NALP3. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like...
| Keywords: | NACHT-, LRR- and PYD-containing Protein 3, NLRP3, Cryopyrin, Cold Autoinflammatory Syndrome 1 Protein |
| Application: | WB |
| Host: | Mouse |
| Species reactivity: | mouse |
462.00€
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Anti-Caspase-4/11 (p20), clone Flamy-1
Item number: AG-20B-0060-C100
Recognizes endogenous full-length protein and activated (p20) fragment of mouse and human caspase-4/11
| Keywords: | Anti-CASP-4, Anti-CASP-11, Anti-Protease ICH-3, Anti-Ich3, EC=3.4.22.64 |
| Application: | WB, IP |
| Host: | Mouse |
| Species reactivity: | human, mouse |
385.00€
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Anti-DNER (human)
Item number: AG-25A-0102-C100
Recognizes human DNER (ED). Detects a band of about 98kDa by Western blot. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. DNER is an activator of the Notch1 pathway. It mediates neuron-glia interaction during astrocytogenesis.
| Keywords: | BET, UNQ262/PRO299, Delta and Notch-like Epidermal Growth Factor-related Receptor |
| Application: | ELISA, WB |
| Host: | Rabbit |
| Species reactivity: | human |
182.00€
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Anti-NALP1/NLRP1 (human) (AL176)
Item number: AG-25B-0005-C100
Recognizes human NLRP1/NALP1. Does not cross-react with mouse NLRP1/NALP1. Liquid. Neat serum containing 0.02% sodium azide. NALP1/NLRP1 is able to form cytoplasmic structures termed death effector filaments. It enhances and stimulates apoptosis through activation of different caspase cascades. It is involved in the...
| Keywords: | NACHT-, LRR- and PYD-containing protein 1, Caspase recruitment domain-containing protein 7, Death effector... |
| Application: | WB |
| Host: | Rabbit |
| Species reactivity: | human |
374.00€
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Fc (human):FasL, Soluble (human) (rec.)
Item number: AG-40B-0132-3010
3 x 10 µg. Human FasL (aa 139-281) is fused at the N-terminus to the Fc portion of human IgG1. Lyophilized. Contains PBS. Fc (human):FasL, Soluble (human) is a high activity construct in which two trimeric FasL are artificially linked via the Fc binding domain of human IgG1. This construct very effectively simulates...
| Keywords: | SPA, APL, FasL, APTL, CD178, FASLG, sFasL, CD95-L, APT1LG1, FasL ICD, Fas ligand, CD95 ligand, Fas antigen ligand, Soluble... |
| Application: | FasL aggregation stimulator |
| Expressed in: | Human cells |
| Origin: | human, mouse |
| MW: | 50 kD |
From 319.00€
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Jak/Src Inhibitor 1 . hydrochloride
Item number: AG-CR1-3647-M001
Yellow solid. Soluble in DMSO. Anticancer compound. Potent antiproliferative agent in vitro and in vivo, Combined inhibitor of pSTAT3 proteins such as JAK, SRC, ABL and class III/V receptor tyrosine kinases (RTK), including FLT3, c-KIT, CSF1-R, PDGFRs and VEGFRs, in nanomolar range.
| Keywords: | Debio 0617B . HCl,... |
| Application: | Anticancer compound |
| CAS | 1332329-27-7 |
| MW: | 618,5 D |
143.00€
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Monosodium urate (crystals)
Item number: AG-CR1-3950-2002
NLRP3/NALP3 inflammasome activator. Specially crystallized and tested for biological activity. Stimulates the caspase-1 activating NLRP3/NALP3 inflammasome, resulting in the production of active IL-1beta and IL-18.
| Keywords: | MSU (crystals), Uric acid (crystals) |
| Application: | NLRP3/NALP3 inflammasome activator |
| Host: | Synthetic |
| CAS | 1198-77-2 |
| MW: | 167,1 D |
From 94.00€
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Fumitremorgin C
Item number: BVT-0189-M001
Mycotoxin, Tremorgenic, Potent and specific inhibitor of the breast cancer resistance protein (BCRP, ABCG2), Reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro. Isolated from Aspergillus fumigatus.
| Keywords: | Tryptoquivaline |
| Application: | Breast cancer resistance protein inhibitor |
| CAS | 118974-02-0 |
| MW: | 379,5 D |
From 90.00€
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Raptinal
Item number: AG-CR1-2902-M005
Beige solid. Soluble in DMSO. Rapid apoptosis inducer that initiates intrinsic pathway caspase-dependent apoptosis within minutes in multiple cell lines and in vivo systems. Exerts anticancer activity in vivo, likely through the induction of apoptosis, Induces cell death against various cancer and non-cancerous cell...
| Keywords: | [9,9'-Bi-9H-fluorene]-9,9'-dicarboxaldehyde, NSC 610970 |
| Application: | Rapid apoptosis inducer |
| CAS | 1176-09-6 |
| MW: | 386,4 D |
From 33.00€
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