Products from AdipoGen Life Sciences
AdipoGen Life Sciences is a manufacturer of reagents for immunometabolism & advanced inflammation research. The headquarters are located in San Diego, USA with a manufacturing laboratory in Switzerland. A motivated team of highly skilled researchers develops new products for the Life Science Reagents Market in the areas cancer, immunology, inflammation, metabolic syndrome (diabetes, obesity), stem cells and neurodegeneration. The major focus is on innovative and advanced ELISA-Kits. In addition to the antibody and protein facilities, AdipoGen also owns chemical laboratories, enabling the company to develop new and innovative biochemicals.
More information at: www.adipogen.com
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PARG Inhibitor PDD00017273
Item number: AG-CR1-3646-M001
White to off-white solid. Soluble in DMSO, methanol or acetonitrile. Human poly(ADP-ribose) glycohydrolase (PARG) inhibitor for in vitro studies, Inhibits human recombinant PARG enzymes (IC50=26nM) and PARG in cell assays (IC50=37nM). Inactive against related glycohydrolases ARH3 and PARP1s (IC50>,30µ,M)....
| Keywords: | PARG Inhibitor Compound 4,... |
| Application: | PARG inhibitor |
| CAS | 1945950-21-9 |
| MW: | 514,6 D |
From 72.00€
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Anti-Gasdermin D (mouse)
Item number: AG-25B-0036-C100
Inflammasomes are multimeric protein complexes that comprise a sensor (e.g. NLRP3), an adaptor (ASC/Pycard) and the procaspase-1. An inflammasome assembles in response to a diverse range of pathogen-associated or danger-associated molecular patterns (PAMPs or DAMPs). The inflammasome platform leads to activation of...
| Keywords: | anti-Gasdermin D (mouse), pAb (IN110) |
| Application: | WB, ELISA |
| Host: | Guinea pig |
| Species reactivity: | mouse |
418.00€
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Anti-TRAIL-R1 (human), clone TR1.02
Item number: AG-20B-0027-C100
Recognizes human TRAIL-R1. Does not cross-react with human TRAIL-R2, -R3 or -R4. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex...
| Keywords: | TRAIL Receptor 1, DR4, APO2, TNFRSF10A, CD261 |
| Application: | FC, IHC, WB |
| Host: | Mouse |
| Species reactivity: | human |
396.00€
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Fc (human):FasL, Soluble (human) (rec.)
Item number: AG-40B-0132-3010
3 x 10 µg. Human FasL (aa 139-281) is fused at the N-terminus to the Fc portion of human IgG1. Lyophilized. Contains PBS. Fc (human):FasL, Soluble (human) is a high activity construct in which two trimeric FasL are artificially linked via the Fc binding domain of human IgG1. This construct very effectively simulates...
| Keywords: | SPA, APL, FasL, APTL, CD178, FASLG, sFasL, CD95-L, APT1LG1, FasL ICD, Fas ligand, CD95 ligand, Fas antigen ligand, Soluble... |
| Application: | FasL aggregation stimulator |
| Expressed in: | Human cells |
| Origin: | human, mouse |
| MW: | 50 kD |
From 319.00€
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Malformin C
Item number: AG-CN2-0107-M001
Peptide antibiotic, induces root curvature and malformation in plants, antibacterial, antimalarial and antitrypanosomal, disrupts the cell cycle at the G2 checkpoint of cancer cells, leading to sensitization of the cancer cells to anti-cancer reagents
| Keywords: | 5-L-Leucine-Malformin A, BRN 4896114, (-)-cyclo[D-Cys(1)-D-Cys(1)-L-Val-D-Leu-L-Leu-] |
| Application: | Apoptosis Inducer |
| CAS | 59926-78-2 |
| MW: | 529,7 D |
From 132.00€
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Pam3Cys-Ser-(Lys)4 . 3HCl
Item number: AG-CP3-0003-M002
Synthetic. Selective agonist of TLR1/TLR2 complex. Cell permeable, water soluble synthetic cationic lipohexapeptide analog of the immunologically active N-terminal portion of bacterial lipoprotein that potently activates monocytes and macrophages. Potent and effective immune adjuvant. Exerts strong local response,...
| Keywords: | Pam3CSK4, Pam3Cys-SKKKK, (S)-[2,3-Bis(palmitoyloxy)-(2- RS)-propyl]-N-palmitoyl-(R)-Cys-(S)-Ser-(S)-Lys 4-OH |
| Application: | TLR1/TLR2 agonist |
| CAS | 112208-00-1 |
| MW: | 1619,7 D |
506.00€
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![alpha-Galactosylceramide Analog I (water soluble) [KBC-007]](https://www.biomol.com/media/image/64/ee/b7/AG-CR1-3608-C100_200x200.png "alpha-Galactosylceramide Analog I (water soluble) [KBC-007]")
alpha-Galactosylceramide Analog I (water soluble) [KBC-007]
Item number: AG-CR1-3608-C100
Synthetic, soluble analog of alpha-galactosylceramide (Prod. No. AG-CN2-0013). Immunostimulant. Potent stimulator of natural killer T (NKT) cells. Specific ligand of the lipid-binding MHC class I-like protein CD1d in human and mouse NKT cells.
| Keywords: | alpha-Gal-Cer Water Soluble Analog, alpha-Galactosylceramide Analog I, alpha-Gal-Cer Analog I |
| Application: | Immunostimulant, CD1d ligand |
| CAS | 1037297-61-2 |
| MW: | 817,2 D |
From 132.00€
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Streptozotocin
Item number: AG-CN2-0046-G001
Antibiotic Diabetogenic. Diabetes inducer. Induces diabetes mellitus in animal models through its toxic effects on pancreatic beta-cells Mutagenic. Potent alkylating agent. Potent DNA methylating agent Nitric oxide (NO) donor. Vasorelaxant. Cytotoxic to cells that express GLUT2 glucose transporter....
| Keywords: | 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose, Streptozocin, STZ, NSC 85998, Antibiotic U9889, Zanosar |
| Application: | Alkylating agent |
| Host: | Synthetic |
| CAS | 18883-66-4 |
| MW: | 265,2 D |
From 33.00€
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Wortmannin
Item number: AG-CN2-0023-M001
Isolated from Penicillium sp. Antibiotic. Potent anti-neutrophil agent with cardioprotective effects. mTOR, DNA-PK, phosphatidylinositol 4-kinases, myosin light chain kinase (MLCK) and mitogen-activated protein kinase (MAPK) inhibitor at high concentrations. Potent cell permeable and selective inhibitor of...
| Keywords: | KY 12420, BRN 0067676, NSC 627609, Antibiotic SL-2052 |
| Application: | PI3 kinase inhibitor, Adipogenesis inhibitor, Angiogenesis inhibitor |
| CAS | 19545-26-7 |
| MW: | 428,4 D |
From 44.00€
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Dihydroartemisinin
Item number: AG-CN2-0468-G001
White solid. Soluble in DMSO or ethanol. Active metabolite of artemisinin, Anti-malaria (Plasmodium), Anti-schistosoma, Apoptosis inducer, Anti-cancer, Anti-inflammatory, Inhibits production of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1) and nitric oxide...
| Keywords: | Dihydroqinghaosu, Artenimol |
| Application: | Artemisinin metabolite, Antimalaria, Antischistosoma, Apoptosis inducer, Anticancer, Antiinflammatory |
| CAS | 71939-50-9 |
| MW: | 284,3 D |
From 50.00€
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![K777 [K11777]](https://www.biomol.com/media/image/e7/bc/7c/AG-CR1-0158-M001_200x200.png "K777 [K11777]")
K777 [K11777]
Item number: AG-CR1-0158-M005
Solid. Soluble in DMSO. Insoluble in water. Potent, irreversible cysteine protease inhibitor, Broad-range cathepsin inhibitor (for all known cathepsins) useful for inflammasome inhibition. Inhibits cathepsins B, L, S, C, V, K and papain in cell-free assays. Inhibits cathepsin X as well, Suppresses particle-induced...
| Keywords: | K-777, K-11777, N-Pip-F-hF-VS Phenyl, N-Pip-phenylalanine-homophenylalanine-vinyl sulfone phenyl,... |
| Application: | Potent irreversible cysteine protease inhibitor |
| CAS | 233277-99-1 |
| MW: | 574,7 D |
From 55.00€
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GW501516
Item number: AG-CR1-3641-M025
White to off-white solid. Soluble in DMSO (30mg/ml), dimethylformamide (30mg/ml), ethanol (10mg/ml) or methanol (30mg/ml). Sparingly soluble in water. Potent and selective peroxisome proliferator-activated receptor (PPAR) delta agonist/activator with high affinity (Ki=1nM) and potency (EC50=1nM) for PPARdelta and...
| Keywords: | GSK-516, GW1516, Endurobol, 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic... |
| Application: | PPARD agonist |
| CAS | 317318-70-0 |
| MW: | 453,5 D |
From 33.00€
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