VEGF/VEGFA protein (His tag), recombinant porcine

Activity: Testing in progress Protein Construction: A DNA sequence encoding the Porcine VEGF/VEGFA protein (P49151) (Ala 27-Arg 190) was expressed with N-His tag. Sequence: Ala 27-Arg 190. Fusion tag: N-His Endotoxin: Please contact us for more information. Apparent Molecular Mass: 20 kDa. Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 re Protein function: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. Also binds the DEAR/FBXW7-AS1 receptor. [The UniProt Consortium]