Stem Cell Factor, rat recombinant (rrSCF)

Stimulates the proliferation of mast cells. Able to augment the proliferation of both myeloid and lymphoid hematopoietic progenitors in bone marrow culture. Mediates also cell-cell adhesion. Acts synergistically with other cytokines, probably interleukins. (www.uniprot.org) Produced in E.coli. Single, non-glycosylated polypeptide chain containing 165 amino acids. The ED50 is determined by the dose-dependant stimulation of the proliferation of human MO7e cells which is < 10 ng/ml.