Pro-Insulin Like Growth Factor-2, HEK, human recombinant (rHupro-IGF2-HEK)

Human recombinant Pro-IGF2 produced in HEK cells is a glycosylated monomer, having a total molecular weight of 25kDa. IGF-2 is a member of the insulin family of polypeptide growth factors that is involved in development and growth. It is an imprinted gene and is expressed only from the paternally inherited allele. It is a candidate gene for eating disorders. There is a read-through, INS-IGF2, which aligns to this gene at the 3' region and to the upstream INS gene at the 5' region. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.