Macrophage Inflammatory Protein-3 alpha (CCL20), human recombinant (rHuMIP-3A)

Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated, polypeptide chain containing 70 amino acids.