Macrophage Colony Stimulating Factor, His Tag, human recombinant (rHuM-CSF-His)

Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy. (www.uniprot.org) Human recombinant Macrophage Colony Stimulating Factor produced in E.coli is a single, non-glycosylated, polypeptide chain containing 179 amino acids (fragment 33-190) and having a total molecular mass of 20.7 kDa. MCSF is fused to a 20 amino acid His Tag at N-terminus. Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy.