Interleukin-6 (IL-6), human recombinant (rHuIL-6)

Human Interleukin-6 (IL-6) plays a role in the mediation of the inflammatory and immune response initiated by infection or injury. IL-6 acts on B cells by stimulating differentiation and antibody secretion. IL-6 also exhibits growth factor activity for mature thymic or peripheral T cells, and enhances the differentiation of cytotoxic T cells in the presence of IL-2 or IFNt. This glycoprotein is composed of 184 aa residues, and has a 42% homology with murine IL-6. Biological Activity: 3H-thymidine uptake by B9 murine thymoma cell line that is IL-6 dependent. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.