Interleukin-2 (IL-2), human recombinant (rHuIL-2)

Human Interleukin-2 (IL-2) is a lymphokine which biological effects include activation and proliferation of T cells, B cells, and other lymphokine activated killer cells. Human IL-2 is composed of 133aa, including 3 cysteine residues, two of which are involved in a disulfide bond essential for biological activity. Human and murine IL-2 are 62% homologous, and human IL-2 has been found to be active on murine cell lines. Biological Activity: The biological activity is determined by a lymphocyte proliferation assay ~160,000 IU (International units). Storage and Stability: Lyophilized powder may be stored at -20°C. Reconstitute to with sterile dH2O, aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.