IL-1beta (human, rec.) (untagged)

(3 x 10µg). Human IL-1beta (amino acids 117-269) is untagged. Activates the NF-kappaB with an ED50 of <5ng/ml. Lyophilized. Contains PBS. IL-1beta is produced by activated macrophages. IL-1beta stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1beta belongs to the IL-1 family of proteins that are involved in the inflammatory response. IL-1beta in most situations requires the inflammasome complex to be cleaved and secreted.