Beta Defensin-3, human recombinant (rHuBD-3)

Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistent E.faecium. No significant hemolytic activity was observed. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated polypeptide chain containing 45 amino acids. Beta-Defensin-3 has a broad spectrum antimicrobial activity and may play an important role in innate epithelial defense.