BAFF (BLyS), His Tag, human recombinant (rHuBAFF-His)

Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated polypeptide chain containing 190 amino acids and having a N-terminal His Tag