Artikelnummer | Größe | Datenblatt | Manual | SDB | Lieferzeit | Menge | Preis |
---|---|---|---|---|---|---|---|
97266.2 | 2 µg | - | - |
3 - 10 Werktage* |
291,00 €
|
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97266.5 | 5 µg | - | - |
3 - 10 Werktage* |
447,00 €
|
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97266.10 | 10 µg | - | - |
3 - 10 Werktage* |
811,00 €
|
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APOD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts. (www.uniprot.org) Human recombinant APO-D full length protein expressed in E.coli shows a 48 kDa band on SDS-PAGE.The Apolipoprotein-D is mainly associated with high density lipoproteins in human plasma. Apolipoprotein-D is an atypical apolipoprotein and, based on its primary structure, Apolipoprotein-D is a member of the lipocalin family. Lipocalins adopt a beta-barrel tertiary structure and transport small hydrophobic ligands. Apolipoprotein-D binds cholesterol, progesterone, pregnenolone, bilirubin and arachidonic acid. Apolipoprotein-D is expressed in numerous tissues having high levels of expression in spleen, testes and brain. Apolipoprotein-D is present at high concentrations in the cyst fluid of women with gross cystic disease of the breast, a condition associated with increased risk of breast cancer. Apolipoprotein-D accumulates in regenerating peripheral nerves and in the cerebrospinal fluid of patients with neurodegenerative conditions, such as Alzheimer's disease. Apolipoprotein-D participates in maintenance and repair within the central and peripheral nervous systems. Apolipoprotein-D is a multi-ligand, multi-functional transporter and transports a ligand from 1 cell to another within an organ, scavenge a ligand within an organ for transport to the blood or could transport a ligand from the circulation to specific cells within a tissue.
Schlagworte: | Apolipoprotein D, Apo-D, ApoD |
Hersteller: | Biomol GmbH |
Hersteller-Nr: | 97266 |
Eigenschaften
Anwendung: | ELISA, WB, Inhibition assays |
Konjugat: | No |
Wirt: | E.coli |
Spezies-Reaktivität: | human |
MW: | 48000 D |
Format: | Purified |
Datenbank Information
KEGG ID : | K03098 | Passende Produkte |
UniProt ID : | P05090 | Passende Produkte |
Handhabung & Sicherheit
Lagerung: | -20°C |
Versand: | +4°C (International: +4°C) |
Nur für Forschungszwecke und Laboruntersuchungen: Nicht für die Anwendung im oder am Menschen!